Results 151 to 160 of about 98,812 (291)

Successful rechallenge with Erwinia chrysanthemi asparaginase after pegaspargase-induced hypertriglyceridemia: a case report

Therapeutic Advances in Hematology
Polyethylene-glycolated Escherichia coli -derived l -asparaginase (pegaspargase, pASP) is an essential component of paediatric-inspired regimens for the treatment of acute lymphoblastic leukaemia/lymphoma; nonetheless, is characterised by severe and ...
Gaia Ciolli, Andrea Pasquini, Francesco Mannelli, Barbara Scappini, Giacomo Gianfaldoni, Elisa Quinti, Laura Fasano, Jessica Caroprese, Francesca Crupi, Alessandro Maria Vannucchi, Matteo Piccini   +10 more
doaj   +1 more source

Managing Hypercholesterolemia in Adults Older Than 75 years Without a History of Atherosclerotic Cardiovascular Disease: An Expert Clinical Consensus From the National Lipid Association and the American Geriatrics Society

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT The risk of atherosclerotic cardiovascular disease increases with advancing age. Elevated LDL‐cholesterol and non‐HDL‐cholesterol levels remain predictive of incident atherosclerotic cardiovascular events among individuals older than 75 years.
Vera Bittner, Sunny A. Linnebur, Dave L. Dixon, Daniel E. Forman, Ariel R. Green, Terry A. Jacobson, Ariela R. Orkaby, Joseph J. Saseen, Salim S. Virani   +8 more
wiley   +1 more source

Association of Perinatal Factors and Family Sociodemographic Characteristics With Cardiometabolic Health in Pre‐Adolescence: Cross‐Sectional Results From Healthy Growth Study

Journal of Paediatrics and Child Health, Volume 61, Issue 5, Page 701-713, May 2025.
ABSTRACT Aim Study the influence of a variety of perinatal factors on the presence of metabolic syndrome and its parameters in prepubertal age, considering socio‐demographic factors, sex, Tanner stage and weight status of the preadolescent. Methods Data collected from the cross‐sectional Healthy Growth Study (2007) in students from four prefectures of ...
Ioanna Nakaki, Aikaterini M. Kontochristopoulou, Costas Anastasiou, George Moschonis, Anela Halilagic, Yingting Cao, Eva Karaglani, Yannis Manios   +7 more
wiley   +1 more source

Gene Expression Shifts in Emperor Penguin Adaptation to the Extreme Antarctic Environment

Molecular Ecology, EarlyView.
ABSTRACT Gene expression can accelerate ecological divergence by rapidly tweaking the response of an organism to novel environments, with more divergent environments exerting stronger selection and supposedly, requiring faster adaptive responses. Organisms adapted to extreme environments provide ideal systems to test this hypothesis, particularly when ...
Josephine R. Paris, Flávia A. Nitta Fernandes, Federica Pirri, Samuele Greco, Marco Gerdol, Alberto Pallavicini, Marine Benoiste, Clément Cornec, Lorenzo Zane, Brian Haas, Céline Le Bohec, Emiliano Trucchi   +11 more
wiley   +1 more source

Weight gain, obesity, and the impact of lifestyle factors among people living with HIV: A systematic review

Obesity Reviews, EarlyView.
Summary HIV remains a significant health concern, but the advent of antiretroviral therapy (ART) has transformed it into a manageable chronic condition. However, weight gain and obesity pose a substantial challenge for people living with HIV (PLWH). Moreover, the role of lifestyle has not yet been comprehensively investigated.
Giulia Gilberti, Giorgio Tiecco, Silvia Marconi, Monica Marullo, Barbara Zanini, Eugenia Quiros‐Roldan   +5 more
wiley   +1 more source

Alternative Splicing Regulation in Metabolic Disorders

Obesity Reviews, EarlyView.
ABSTRACT Alternative splicing (AS) is a fundamental mechanism for enhancing transcriptome diversity and regulating gene expression, crucial for various cellular processes and the development of complex traits. This review examines the role of AS in metabolic disorders, including obesity, weight loss, dyslipidemias, and metabolic syndrome.
Dorota Kaminska
wiley   +1 more source

Insulin resistance, overweight, and obesity in apheresis donors: A call to reevaluate their eligibility—A prospective cohort study

Transfusion, EarlyView.
Abstract Background Apheresis procedures and the infusion of acid‐citrate‐dextrose induce metabolic alterations that may influence glucose metabolism. Although insulin resistance (IR), overweight, and obesity are not exclusion criteria for blood donation, their impact during apheresis procedure and on post‐donation metabolic responses remains ...
Edgar Barrientos‐Galeana, Gabriela Chico‐Barba, Mari Cruz Tolentino‐Dolores, Emmanuel Fernández‐Sánchez, Rosa María Morales‐Hernández, Selene Barragán‐Montes, Maria de los Angeles Rosales‐López, Raymundo Rodríguez‐Jurado, Ángel Sebastián Quebrado‐Benítez, María‐Cristina Ramírez‐González, Heriberto López‐Martínez, Noemi Hernández‐Cruz, Jannyn Herrera‐Juárez, Karla Eugenia Bermúdez‐Ferro, Rodrigo Castillo‐Llanos   +14 more
wiley   +1 more source

Abnormal bile acid absorption in familial hypertriglyceridemia

Journal of Lipid Research, 1995
To better define the abnormality of bile acid metabolism associated with hypertriglyceridemia, we measured bile acid kinetics and absorption as well as preferential use of newly synthesized cholesterol for bile acid synthesis in eleven controls and ten ...
W C Duane
doaj  

A Phase 1/2 Study of Lenvatinib in Combination With Everolimus in Recurrent and Refractory Pediatric and Young Adult Solid Tumors

Pediatric Blood &Cancer, Volume 72, Issue 7, July 2025.
ABSTRACT Introduction Developing targeted therapies with manageable toxicities remains a high priority for pediatric cancer. We sought to determine the recommended Phase 2 dose (RP2D) and evaluate the antitumor activity of lenvatinib+everolimus in children/young adults with select recurrent/refractory solid tumors.
Filemon S. Dela Cruz, Elizabeth Fox, Steven G. DuBois, Gregory K. Friedman, James M. Croop, AeRang Kim, Daniel A. Morgenstern, Frank M. Balis, Margaret E. Macy, Joseph G. Pressey, Tanya Watt, Julie I. Krystal, Kieuhoa T. Vo, Rajen Mody, Theodore W. Laetsch, Brenda J. Weigel, Karen O'Hara, Cixin S. He, Jagadeesh Aluri, Chinyere E. Okpara, Julia L. Glade Bender   +20 more
wiley   +1 more source

Lipid composition of fat particles from normal man and patients with idiopathic hypertriglyceridemia

, 1966
Daniel Porte, David Ohara, Robert H. Williams   +2 more
openalex   +1 more source