INSIG1 influences obesity-related hypertriglyceridemia in humans [PDF]
, 2010 In our analysis of a quantitative trait locus (QTL) for plasma triglyceride (TG) levels [logarithm of odds (LOD) = 3.7] on human chromosome 7q36, we examined 29 single nucleotide polymorphisms (SNPs) across INSIG1, a biological candidate gene in the ...
A.H. Kissebah +58 more
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Managing Hypertriglyceridemia in Daily Practice
Acta Medica Indonesiana, 2015 Hypertriglyceridemia is a form of dyslipidemia, which usually occurs in combination with hypercholesterolemia, high-LDL or low-HDL cholesterol level.
Laurentius A Pramono, Dante S Harbuwono
doaj +4 more sources
Macrophage Activation Syndrome as Onset of Systemic Lupus Erythematosus: A Case Report and a Review of the Literature [PDF]
, 2015 Macrophage activation syndrome (MAS) is a potentially fatal condition. It is a rare complication of several autoimmune disorders, including systemic lupus erythematosus (SLE) and systemic juvenile idiopathic arthritis (sJIA).
Didona, Dario +4 more
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Clinical and Genetic Risk Factors Associated with Psoriatic Arthritis among Patients with Psoriasis. [PDF]
, 2018 IntroductionPsoriatic arthritis (PsA) is a chronic, inflammatory arthritis that affects an estimated 30% of patients with psoriasis. PsA is underdiagnosed in primary care and dermatology clinics due to a variety of reasons, including failure of ...
Ahn, Richard +3 more
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Familial Chylomicronemia Syndrome-Induced Acute Necrotizing Pancreatitis during Pregnancy
Revista Brasileira de Ginecologia e Obstetrícia, 2021 Acute pancreatitis is a rare condition in pregnancy, associated with a high mortality rate. Hypertriglyceridemia represents its second most common cause.We present the case of a 38-year-old woman in the 24th week of gestation with a history of ...
Julia Cristina Coronado Arroyo +5 more
doaj +1 more source
Hypertriglyceridemia and atherosclerosis [PDF]
Lipids in Health and Disease, 2017 Atherosclerotic cardiovascular disease (ASCVD) is the leading cause of death and it has been confirmed that increased low density lipoprotein cholesterol (LDL-C) is an independent risk factor for atherosclerosis. Recently, the increasing evidence has showed that hypertriglyceridemia is associated with incremental ASCVD risk.
Jia Peng +4 more
openaire +3 more sources
Adiponectin Deficiency Impairs Maternal Metabolic Adaptation to Pregnancy in Mice. [PDF]
, 2017 Hypoadiponectinemia has been widely observed in patients with gestational diabetes mellitus (GDM). To investigate the causal role of hypoadiponectinemia in GDM, adiponectin gene knockout (Adipoq-/- ) and wild-type (WT) mice were crossed to produce ...
Hay, William W +6 more
core +1 more source
ApoE isoform leading to hypertriglyceridemia in new onset type 1 diabetes
Clinical Case Reports, 2018 Key Clinical Message We report a case of pediatric diabetic ketoacidosis (DKA) with significant hypertriglyceridemia. The patient was found to have the e3/ e4 isoform of ApoE, increasing risk of hypertriglyceridemia in DKA.
Christel Keefe, Sarah Lawson
doaj +1 more source
COVID-19-associated hypertriglyceridemia and impact of treatment
Frontiers in MedicineBackgroundCoronavirus disease 2019 (COVID-19) associated hypertriglyceridemia was observed among patients admitted to intensive care units (ICU) in Qatar.
Rasha Kaddoura +6 more
doaj +1 more source
Apoc2 loss-of-function zebrafish mutant as a genetic model of hyperlipidemia
Disease Models & Mechanisms, 2015 Apolipoprotein C-II (APOC2) is an obligatory activator of lipoprotein lipase. Human patients with APOC2 deficiency display severe hypertriglyceridemia while consuming a normal diet, often manifesting xanthomas, lipemia retinalis and pancreatitis ...
Chao Liu +13 more
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