Results 71 to 80 of about 68,532 (268)

Loss-of-Function CREB3L3 Variants in Patients With Severe Hypertriglyceridemia

Arteriosclerosis, Thrombosis and Vascular Biology, 2020
Supplemental Digital Content is available in the text. Objective: Genetic determinants of severe hypertriglyceridemia include both common variants with small effects (assessed using polygenic risk scores) plus heterozygous and homozygous rare variants in
J. Dron, A. Dilliott, Arden Lawson, A. McIntyre, Brent D. Davis, Jian Wang, H. Cao, I. Movsesyan, M. Malloy, C. Pullinger, J. Kane, R. Hegele   +11 more
semanticscholar   +1 more source

Photoperiod‐Dependent Effects of Phenolic‐Enriched Fruit Extracts on Postprandial Triacylglyceride Levels and Acute Inflammatory Responses in F344 Rats

Molecular Nutrition &Food Research, EarlyView.
This study investigates the photoperiod‐dependent effects of eight phenolic‐rich fruit extracts on postprandial blood triacylglyceride (TAG) levels and serum inflammatory markers in F344 rats, following an oral lipid tolerance test (OLTT) and a lipopolysaccharide (LPS)‐induced inflammatory challenge. Results showed that cherry and plum extracts reduced
Francesca Manocchio, Diego Morales, Èlia Navarro‐Masip, Gerard Aragones, Cristina Torres‐Fuentes, Francisca Isabel Bravo, Begoña Muguerza   +6 more
wiley   +1 more source

Histogram-based Sub-classification of Serum Triglycerides and Hypertriglyceridemia Prevalence Across Gender and Age Groups: A Cross-sectional Study [PDF]

Journal of Clinical and Diagnostic Research
Introduction: The ICMR-Indiab study (2014) and National Centres for Environmental Prediction (NCEP) (2001) guidelines recommended a healthy cut-off for serum triglycerides of
Chekkara Muthu Shaima, Jose Jacob
doaj   +1 more source

Population Pharmacokinetics and Exposure‐Response Modeling for Evinacumab in Children, Adolescents, and Adults With Homozygous Familial Hypercholesterolemia

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Evinacumab, an angiopoietin‐like 3 (ANGPTL3) inhibitor, significantly reduces low‐density lipoprotein cholesterol (LDL‐C), independent of low‐density lipoprotein receptor, in patients with homozygous familial hypercholesterolemia (HoFH). A population pharmacokinetic (PK)/pharmacodynamic (PD) model was previously developed to characterize ...
Sébastien Bihorel, Robert Dingman, Jeanne Mendell, Yuhuan Wang, Poulabi Banerjee, Robert Pordy, John D. Davis, A. Thomas DiCioccio, Lutz Harnisch   +8 more
wiley   +1 more source

A Woman with Pancreatitis and Hypertriglyceridemia [PDF]

Clinical Chemistry, 2019
A woman presented to the emergency department with abdominal pain, nausea, and vomiting. On examination, she had abdominal tenderness and a medical history of diabetes mellitus type 1, hypertension, end-stage renal disease, liver disease (hepatic steatosis), hypothyroidism, chronic obstructive pulmonary disease, and congestive heart failure.
Ayesha Farooq, Angela Treml, Jessica M Colón-Franco   +2 more
openaire   +3 more sources

Individualized Lung‐Protective Ventilation Strategy Based on Esophageal Pressure Monitoring in Patients With ARDS Associated With Severe Acute Pancreatitis—A Randomized Controlled Trial

World Journal of Surgery, EarlyView.
Acute respiratory distress syndrome (ARDS) secondary to severe acute pancreatitis (SAP) presents significant management challenges with high mortality rates. This study aimed to investigate the application value of an individualized lung‐protective ventilation strategy guided by esophageal pressure (Pes) monitoring in patients with ARDS associated with
Yang Zhao, Shengxuan Zhang, Chengjiang Liu, Xiaoxia Wang   +3 more
wiley   +1 more source

Asparaginase-Induced Hypertriglyceridemia Presenting as Pseudohyponatremia during Leukemia Treatment

Case Reports in Pediatrics, 2014
Asparaginase is a chemotherapeutic agent used to induce disease remission in children with acute lymphoblastic leukemia (ALL). We describe the cases of two females with ALL who developed pseudohyponatremia as a presentation of hypertriglyceridemia ...
Ashley Hinson, Dorothee Newbern, Corinne M. Linardic   +2 more
doaj   +1 more source

Influence of patient factors on target plasma volume treated attainment rate during double filtration plasmapheresis in patients with hypertriglyceridemic acute pancreatitis

Therapeutic Apheresis and Dialysis, EarlyView.
Abstract Introduction This study aims to investigate patient factors affecting the rate of plasma volume target attained in hypertriglyceridemic pancreatitis (HTG‐AP) patients undergoing double filtration plasmapheresis (DFPP). Methods A retrospective analysis of 82 HTG‐AP‐interpreted patients from January 2019 to April 2024 compared target plasma ...
Hui Zhang, Chenqiang Zhu, Yunlong Wu
wiley   +1 more source

The Incidence of Propofol-Induced Hypertriglyceridemia and Identification of Associated Risk Factors

Critical Care Explorations, 2020
Supplemental Digital Content is available in the text. Objectives: The objective of this study was to describe the incidence of propofol-induced hypertriglyceridemia and the risk factors associated with hypertriglyceridemia in mechanically ventilated ICU
Michael J Corrado, Mary P. Kovacevic, Kevin M. Dube, Kenneth E. Lupi, P. Szumita, Jeremy R. DeGrado   +5 more
semanticscholar   +1 more source

Gut Microbiota Regulate Lipid Metabolism via the Bile Acid Pathway: Resistance to Hypoxia in Gansu Zokor (Eospalax cansus)

Integrative Zoology, EarlyView.
The gut microbiota regulates lipid metabolism of Gansu zokor (Eospalax cansus) through the bile acid pathway in hypoxic environments, reflecting the unique survival strategy of subterranean rodents to maintain lipid metabolism homeostasis and flexible energy metabolism in hypoxic environments.
Maohong Yang, Yingying Zhang, Zhuohang Li, Tianyi Liu, Jianping He, Jingang Li   +5 more
wiley   +1 more source