Results 151 to 160 of about 125,690 (294)

The association between the clinical severity of heart failure and docosahexaenoic acid accumulation in hypertrophic cardiomyopathy [PDF]

, 2022
Keitaro Akita, Kenji Kikushima, Takenori Ikoma, Ariful Islam, Tomohito Sato, Taisei Yamamoto, Tomoaki Kahyo, Mitsutoshi Setou, Yuichiro Maekawa   +8 more
openalex   +1 more source

Peptidomics in Different Phases of Severe Acute Pancreatitis Model

PROTEOMICS – Clinical Applications, EarlyView.
ABSTRACT Severe acute pancreatitis (SAP) involves dynamic shifts from inflammation to immunosuppression, where peptidomic profile evolution may reveal prognostic biomarkers. Here, the plasma peptidome of rats with taurocholate‐induced SAP at 1, 3, 6, 12, and 24 h compared with controls was characterized using nLC‐MS/MS.
Roberto Rasslan, Marcia Kiyomi Koike, Marcel Cerqueira Cesar Machado, Luiz Felipe Martucci, Leo Kei Iwai, Rosangela Aparecida dos Santos Eichler, Edivaldo Massazo Utiyama, Emer Suavinho Ferro, Edna Frasson de Souza Montero   +8 more
wiley   +1 more source

Exploring RNA-targeted gene therapy approaches for hypertrophic cardiomyopathy [PDF]

, 2012
Relatório de projeto no âmbito do Programa de Bolsas Universidade de Lisboa/Fundação Amadeu Dias (2011/2012). Universidade de Lisboa.
Freitas, Ana
core  

Seventeen year follow-up of a patient with hypertrophic cardiomyopathy which progressed to dilated cardiomyopathy.

, 1984
Mikiko FUNAKOSHI, Mitsuhide Imamura, Jun SASAKI, Masanori Fujino, Tomoki Kawano, Yasushi Sasaki, Yoshiyuki Nakashima, Tadashi Motooka, Keisuke Fukuda, Misao IMAGAWA, Tadayuki Hiroki, Kikuo Arakawa   +11 more
openalex   +2 more sources

Toward a Quantitative Understanding of Aficamten Clinical Pharmacology: Population Pharmacokinetic Modeling

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Aficamten is a next‐in‐class, cardiac myosin inhibitor in development as a potential chronic oral treatment for patients with hypertrophic cardiomyopathy (HCM). A population pharmacokinetic (PK) model was developed using data from nine clinical studies to characterize aficamten PK and identify covariates that may alter aficamten exposure ...
Donghong Xu, Hanbin Li, Stephen B. Heitner, Daniel L. Jacoby, Stuart Kupfer, Polina German, Justin Lutz   +6 more
wiley   +1 more source

Genotypic and Phenotypic Correlation Regarding Expression Level of Myosin Heavy Chain (Myh7) Gene Polymorphisms in Hypertrophic Cardiomyopathy

, 2018
Dilshani Wanshika
openalex   +1 more source

Initial investigations into single nucleotide polymorphisms and their association with QTc and left ventricular function in peripartum cardiomyopathy

European Journal of Heart Failure, EarlyView.
Gasnat Shaboodien, Charle Viljoen, Polycarp Ndibangwi, Julian Hoevelmann, Lameez Pearce, Susanna Haidari, Margherita Torchio, Federica Dagradi, Carla Spazzolini, Sarah Kraus, Ntobeko A.B. Ntusi, Peter J. Schwartz, Karen Sliwa   +12 more
wiley   +1 more source

Mitochondrial dynamics in autoimmune diseases

Rheumatology &Autoimmunity, EarlyView.
Roles of mitochondrial dynamic imbalance in autoimmune diseases. The imbalance of mitochondrial fusion and fission is involved in the occurrence and development of autoimmune diseases, including systemic lupus erythematosus, Sjogren's syndrome, rheumatoid arthritis, multiple sclerosis, myasthenia gravis, type 1 diabetes, psoriasis, and autoimmune ...
Ruicong Ma, Cheng Zhang, Jiaqing Liu, Jinyi Ren, Xia Li, Ying Zhao   +5 more
wiley   +1 more source

On-pump intracardiac echocardiography during septal myectomy for hypertrophic cardiomyopathyCentral Message

JTCVS Techniques, 2020
David M. Williams, MD, Robert G. Nampi, MD, Muhamed Saric, MD, PhD, Eugene A. Grossi, MD, Mark V. Sherrid, MD, Daniel G. Swistel, MD   +5 more
doaj   +1 more source

Reduced Mitochondrial Adenine Nucleotide Translocase 1 (ANT1) Correlates With Aging‐Associated Airway Remodeling

Aging Cell, EarlyView.
Adenine nucleotide translocase 1 (ANT1), a mitochondrial ATP transporter, is decreased in the lung epithelium of aged adults and aged mice correlating to pathogenic airway changes. Loss of ANT1 correlates with increased cellular senescence and changes in COL8A1 in the airway epithelium of the lung.
Roshani Jha, Jian Shi, Maggie J. Sedgwick, Justin Sui, Timothy E. Corcoran, Corrine R. Kliment   +5 more
wiley   +1 more source