Results 181 to 190 of about 128,678 (309)

Multimodality imaging in hypertrophic cardiomyopathy. [PDF]

J Cardiovasc Imaging
Kim J, Lee SC.
europepmc   +1 more source

Primary cardiac lymphoma masquerading as hypertrophic cardiomyopathy: The diagnostic value of cardiovascular magnetic resonance and assessing response to treatment.

Meshal Faleh Alenezi, Raad Mohiaddin
openalex   +1 more source

Promoting Autophagy Mitigates Stress‐Induced Remodeling in Patient iPSC‐CMs with the Phospholamban R9C Mutation

Advanced Science, Volume 13, Issue 7, 3 February 2026.
The Phospholamban (PLN) R9C mutation reduces SERCA2a binding, increasing calcium recycling and baseline contractility. However, the excess of free PLN promotes pentamer formation, limiting phosphorylation and blunting β‐adrenergic signaling. Under cardiac stress, enhanced functional demands overwhelm proteostasis in PLN R9C cells, leading to misfolded ...
Qi Yu, Yawei Shen, Robert J. Barndt, Karim Sallam, Ying Tang, Cameron E. Brown, Xiao Li, Stephen Y. Chan, Joseph C. Wu, Qing Liu, Haodi Wu   +10 more
wiley   +1 more source

Correction: Mechanisms of metabolic transition in hypertrophic cardiomyopathy. [PDF]

Front Physiol
Tan C, Guo Z, Zhou J, Yuan W.
europepmc   +1 more source

The HRAS Variant c.175G>A (p.Ala59Thr) Causes a Predominantly Ectodermal Phenotype Lacking Classic Costello Syndrome Features

American Journal of Medical Genetics Part A, Volume 200, Issue 2, Page 407-418, February 2026.
ABSTRACT Costello syndrome (CS) is a rare dominant HRAS RASopathy characterized by curly hair, cardiac abnormalities, craniofacial anomalies, and developmental delay. HRAS codon 58, 59, and 60 variants are associated with milder phenotypes. We describe a three‐generation family with a previously unreported heterozygous HRAS variant c.175G>A (p.Ala59Thr)
Nikole Rautiainen, Eveliina Brandt, Kaisa Kettunen, Outi Elomaa, Sirpa Kivirikko, Leila Jeskanen, Katriina Lappalainen, Nelli Sjöblom, Juha Kere, Katariina Hannula‐Jouppi, Liisa Harjama   +10 more
wiley   +1 more source

Indications for Surgery in Obstructive Hypertrophic Cardiomyopathy

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Mark V. Sherrid
doaj   +1 more source

Case Report: Hypertrophic cardiomyopathy meets left ventricular hypertrabeculation: from mixed cardiomyopathy to hypertrophic cardiomyopathy with hypertrabeculation. [PDF]

Front Cardiovasc Med
Li Y, Liu Y, Zheng X, Chen L, Dai Q, Ma G.   +5 more
europepmc   +1 more source

A Genotype-phenotype Taxonomy of Hypertrophic Cardiomyopathy

Lara Curran, Antonio de Marvao, Paolo Inglese, Kathryn A. McGurk, Adam Clement, Sean L. Zheng, Surui Li, Chee Jian Pua, Mit Shah, Mina Jafari, Pantazis Theotokis, Rachel Buchan, Sean J. Jurgens, Claire E. Raphael, John Baksi, Antonios Pantazis, Brian P. Halliday, Dudley J. Pennell, Wenjia Bai, Calvin Chin, Rafik Tadros, Connie R. Bezzina, Hugh Watkins, Stuart A. Cook, Sanjay Prasad, James S. Ware, Declan P. O’Regan   +26 more
openalex   +1 more source

Clinical characteristics and long‐term outcomes in patients with apical hypertrophic cardiomyopathy [PDF]

Meng Guo, Chuanfen Liu, Jingjing Ye, Jian Liu   +3 more
openalex   +1 more source

CYP2C19 genotype testing for clopidogrel: A guideline developed by the UK Centre of Excellence in Regulatory Science and Innovation in Pharmacogenomics (CERSI‐PGx)

British Journal of Clinical Pharmacology, Volume 92, Issue 2, Page 329-347, February 2026.
Clopidogrel, an antiplatelet agent, is currently licensed in the United Kingdom for the prevention and treatment of atherothrombotic events in cerebrovascular disease, coronary artery disease and peripheral arterial disease. Clopidogrel requires metabolic activation by the cytochrome P450 enzyme CYP2C19 to be effective.
Cinzia Dello Russo, Iain Frater, Rebecca Kuruvilla, Stefanie Lip, Hannah O'Neill, Kerry Burke, Vicky Chaplin, Alexander S. F. Doney, Salim Elyas, Nicholas Greaves, Sophie Harding, David Hargroves, Judith Hayward, Dyfrig A. Hughes, Tom A. T. Hughes, Sree Kondapally, Patrick Mok, Aaron Peace, Imran Rafi, Simon Ray, Vicky Stinton, Luigi Venetucci, Munir Pirmohamed   +22 more
wiley   +1 more source