Results 211 to 220 of about 192,948 (305)

Proteomic Biomarkers Are Linked to QTc Interval in Patients With Chronic Heart Failure

PROTEOMICS – Clinical Applications, EarlyView.
ABSTRACT Objective This study investigates the link between circulating proteins and rate‐corrected QT (QTc) interval in patients with heart failure with reduced ejection fraction (HFrEF) and their association with cardiovascular outcomes. Methods and Results We analyzed 197 HFrEF patients from the prospective Serial Biomarker Measurements and New ...
Mylène Barry‐Loncq de Jong, Teun B. Petersen, Sabrina Abou Kamar, Navin Suthahar, Nick van Boven, K. Martijn Akkerhuis, Peter J. van der Spek, Peter D. Katsikis, Rudolf A. de Boer, Victor A. W. M. Umans, Eric Boersma, Folkert W. Asselbergs, Jasper J. Brugts, Sing‐Chien Yap, Isabella Kardys   +14 more
wiley   +1 more source

Unlocking Hopeaphenol: A Potent Ally Against Cardiac Hypertrophy via AMPK Activation. [PDF]

Nutrients
Chen J, Wang M, Zhang Z, Fang C, Zhuang H, Zhao J, Wang T, Wang J, Li C, Fang C.   +9 more
europepmc   +1 more source

Impact of Lipid Profile Alterations on the Right Heart Function and Prognosis in Pre‐Capillary Pulmonary Hypertension Patients: A Prospective Cohort Study

Respirology, EarlyView.
This study found that reduced HDL‐C correlates with impaired RV systolic function and RA strain, highlighting a mechanistic link between lipid abnormalities and right heart remodelling. Additionally, decreased HDL‐C and LDL‐C were identified as independent mortality predictors in precPH patients. Integrating lipid parameters into ESC and ESC‐CMR models
Jiajun Guo, Ji Zhao, Jiaqi Wang, Yangjie Li, Juan He, Chen Chen, Xuhan Liu, Lidan Yin, Shoufang Pu, Bi Wen, Min Luo, Yuanwei Xu, Ke Wan, Yuchi Han, Yucheng Chen   +14 more
wiley   +1 more source

Silent Myocardial Ischemia in CKD Stage 3-5: Prevalence and Predictors. [PDF]

Cureus
Ali WB, Tariq T, Raashid Sidhu A, Anan S, Jannat S, Tayyab M, Ahmad M, Mushtaq U.   +7 more
europepmc   +1 more source

Lung‐Derived Small Extracellular Vesicles Containing miR‐15a‐5p/miR‐96‐5p Promote Myocardial Fibrosis in Hypertrophic Cardiomyopathy via Targeting SMAD7

Small, EarlyView.
Small extracellular vesicles (sEVs) are critical regulators of inter‐tissue communication in cardiovascular diseases. In this study, it is found that lung‐derived sEVs enhance cardiac fibroblasts activation and aggravates myocardial fibrosis progression in hypertrophic cardiomyopathy (HCM). sEVmiR‐15a‐5p and sEVmiR‐96‐5p exert this effect via targeting
Minwen Long, Jinpeng Sun, Dongli Zhou, Can Chen, Jiangcheng Shu, Xiaobo Mao, Kunwu Yu, Minglu Liang, Long Chen, Yumei Wang, Min Cheng   +10 more
wiley   +1 more source

Subclinical Myocardial Dysfunction in Type 2 Diabetes Mellitus: Insights from Left Ventricular Diastolic Function and Global Longitudinal Strain Assessment. [PDF]

Med Sci (Basel)
Nghiem TP, Tran HM, Nguyen DNQ, Dao LT, Tran CC, Vo TM.   +5 more
europepmc   +1 more source

Substrate Stiffness Modulates Fibroblast Extracellular Vesicle Secretion Via Mechanotransduction Pathways

Small, EarlyView.
Substrate stiffness shows modulation of the size and proteomic composition of mammary and cardiac fibroblast‐derived extracellular vesicles (EVs). Proteomics analyses and key protein inhibition studies reveal mechanotransduction pathways that regulate this stiffness‐tuned EV biogenesis in fibroblasts, offer new insight into how mechanical cues shape ...
Jun Yang, Lara Ece Celebi, Lauren Hawthorne, S. Gulberk Ozcebe, Pinar Zorlutuna   +4 more
wiley   +1 more source

Percutaneous intramyocardial septal radiofrequency ablation: a novel treatment for drug-refractory non-obstructive hypertrophic cardiomyopathy with severe septal hypertrophy. [PDF]

Heart
Wang H, Li J, Hsi DH, Li W, Ta S, Jiao Y, Shan B, Chang L, Ou X, Yao L, Wang B, Wang J, Lei C, Liu L.   +13 more
europepmc   +1 more source

Comprehensive improvement in cardiac function following myosin inhibition after the ineffectiveness of myectomy and alcohol septal ablation: a case report. [PDF]

Eur Heart J Case Rep
Aleksandrov A, Haverkamp W, Borges AC, Zöller T, Knebel F.   +4 more
europepmc   +1 more source

Fetal cardiac remodeling in second trimester in pregnancies with pre‐eclampsia and/or fetal growth restriction: deep‐learning‐based approach using population‐wide data

Ultrasound in Obstetrics &Gynecology, EarlyView.
ABSTRACT Objective Pre‐eclampsia (PE) and fetal growth restriction (FGR) have been shown to impact fetal cardiac remodeling in the third trimester and postnatally, with evidence to suggest that this leads to increased long‐term cardiovascular risk. This study aimed to examine fetal cardiac remodeling in pregnancies with PE and/or FGR during the second ...
C. A. Taksøe‐Vester, K. Mikolaj, O. B. Petersen, C. K. Ekelund, N. G. Vejlstrup, C. Vedel, A. N. Christensen, A. Feragen, M. Nielsen, M. G. Tolsgaard   +9 more
wiley   +1 more source