Results 61 to 70 of about 140,079 (313)

Aortic calcification and femoral bone density are independently associated with left ventricular mass in patients with chronic kidney disease [PDF]

, 2012
Background Vascular calcification and reduced bone density are prevalent in chronic kidney disease and linked to increased cardiovascular risk. The mechanism is unknown.
Moody William E., Edwards, Nicola C., Crabtree Nicola J., Steeds, Richard P., Colin D Chue, Chue, Colin D., Steeds Richard P., Ferro Charles J., Charles J Ferro, Nadezhda A Wall, Townend, Jonathan N., Ferro, Charles J., Zehnder Daniel, Zehnder, Daniel, Daniel Zehnder, Moody, William E., Chue Colin D., Edwards Nicola C., Nicola C Edwards, Richard P Steeds, Jonathan N Townend, Wall Nadezhda A., Nicola J Crabtree, William E Moody, Crabtree, Nicola J., Wall, Nadezhda A., Townend Jonathan N.   +26 more
core   +1 more source

The E3 Ligase RNF115 Aggravates Pathological Cardiac Hypertrophy via Ubiquitin‐Mediated Degradation of SPTBN1

Advanced Science, EarlyView.
In response to hypertrophic stimuli, increased c‑JUN phosphorylation upregulates RNF115, leading to SPTBN1 ubiquitination and degradation. which promotes F‑actin depolymerization and YAP activation, driving cardiac hypertrophy. The RNF115 inhibitor DTD effectively suppresses SPTBN1 ubiquitination and cardiac hypertrophy.
Yan Zu, Shiqing Chen, Ji Chen, Liuliu Ruan, Bowen Li, Weijian Chu, Shichen Huang, Dian Yu, Jing Tian, Yuhan Zhao, Yi Han, Xin Tang, Yong Ji   +12 more
wiley   +1 more source

Prognostic Implications of Left Ventricular Hypertrophy [PDF]

Progress in Cardiovascular Diseases, 2018
Left ventricular hypertrophy (LVH) was one of the earliest studied echocardiographic characteristics of the left ventricle. As the myriad of measurable metrics has multiplied over recent years, this reliable and relevant variable can often be overlooked. In this paper, we discuss appropriate techniques for accurate analysis, underlying pathophysiology,
Stewart, Merrill H., Lavie, Carl J., Shah, Sangeeta, Englert, Joseph, Gilliland, Yvonne, Qamruddin, Salima, Dinshaw, Homeyar, Cash, Michael, Ventura, Hector, Milani, Richard   +9 more
openaire   +5 more sources

The incidence and risk factors for new onset atrial fibrillation in the PROSPER study [PDF]

, 2011
Aims Atrial fibrillation/flutter (AF) is the most common arrhythmia in older people. It associates with reduced exercise capacity, increased risk of stroke, and mortality. We aimed to determine retrospectively whether pravastatin reduces the incidence of
Jukema, J.W., R. G. J. Westendorp, Westendorp, R.G.J., P. W. Macfarlane, Sattar, N., J. W. Jukema, Ford, I., D. J. Stott, J. Shepherd, H. Murray, Buckley, B., Murray, H., N. Sattar, B. Buckley, Macfarlane, P.W., Stott, D.J., I. Ford, Shepherd, J.   +17 more
core   +1 more source

ZER1 Restrains Pressure Overload‐Induced Cardiac Remodeling by Targeting DVL2 for Gly/N‐Degron‐Dependent Degradation

Advanced Science, EarlyView.
Pressure overload suppresses cardiomyocyte ZER1, weakening CRL2Zer1‐mediated DVL2 degradation and allowing DVL2 accumulation. Elevated DVL2 activates CaMKII‐HDAC4‐MEF2C signaling, drives fetal gene reactivation, and promotes pathological remodeling.
Mingchao Jiang, Zhehao Lin, Lu Chen, Ying Ni, Jun Zhou, Wenjuan Zhang, Huilin Wang, Peifeng Ying, Xiu Lu, Kai Wang, Qingran Kong, Naxin Xu, Dingsheng Zhao, Jianwei Li, Guohui Zhong, Xingchen Meng, Sarkawt Hamad, Junmeng Zheng, Yuan Fu, Rongjiang Qin, Xuran Chu, Shangxuan Li, Youyou Li, Yili Wu, Yi Wang, Weihong Song, Yingxian Li, Shukuan Ling   +27 more
wiley   +1 more source

PREVALENCE OF LEFT VENTRICULAR HYPERTROPHY IN NEWLY DIAGNOSED HYPERTENSIVE PATIENTS

Pakistan Armed Forces Medical Journal, 2020
Objective: To detect frequency of left ventricular hypertrophy in patients with newly diagnosed hypertension. Study Design: Cross sectional study. Place and Duration of Study: Out patient and inpatient, Department of Medicine of Combined Military ...
Umair Masood, Ali Javed, Fariha Ashraf, Umar Javed, Abdul Wahab Siddique, Qasim Zaheer   +5 more
doaj  

Quantitative analysis of cardiac left ventricular variables obtained by MRI at 3 T : a pre- and post-contrast comparison

, 2012
Short-axis cine images are acquired during cardiac MRI in order to determine variables of cardiac left ventricular (LV) function such as ejection fraction (EF), end-diastolic volume (EDV), end-systolic volume (ESV), stroke volume (SV) and LV mass.
Crowe, E. A., J G Houston, Houston, J. G., Lerski, R. A., R S Nicholas, S Matthew, S J Gandy, Gandy, S. J., Nicholas, R. S., Dunn, M. H., R A Lerski, E A Crowe, Waugh, S. A., S A Waugh, Matthew, S., M H Dunn   +15 more
core   +1 more source

AI‐Assisted IoT‐Enabled ECG Monitoring: Integrating Foundational and Generative AI Tools for Sustainable Smart Healthcare—Recent Trends

AI &Innovation, EarlyView.
ABSTRACT The rapid evolution of the Internet of Things (IoT) has significantly advanced the field of electrocardiogram (ECG) monitoring, enabling real‐time, remote, and patient‐centric cardiac care. This paper presents a comprehensive survey of AI assisted IoT‐based ECG monitoring systems, focusing on the integration of emerging technologies such as ...
Amrita Choudhury, Kandarpa Kumar Sarma, Lachit Dutta   +2 more
wiley   +1 more source

Resolution of Refractory Multifocal Atrial Tachycardia in Costello Syndrome Using Trametinib: A Case Supporting MEK Inhibitors as Targeted, Specific Antiarrhythmic

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Arrhythmias affect approximately half of patients with Costello syndrome (CS, OMIM # 218040), with non‐reentrant atrial tachycardia being the most common. This case describes an infant with Costello syndrome carrying the pathogenic HRAS c.34G>A (p.G12S) variant who developed early‐onset, drug‐refractory multifocal atrial tachycardia (MAT ...
Vanina Taliercio, Annabelle Wilcox, Stacey Cole, Josue Flores Daboub, José E. Morales Moreno, Kasey G. Andrews, S. Yukiko Asaki, Thomas A. Pilcher, Martin Tristani‐Firouzi, Mary C. Niu, David Viskochil, Benjamin Hammond   +11 more
wiley   +1 more source

Distribution of cardiac geometric patterns on echocardiography in essential hypertension. Impact of two criteria of stratification

Arquivos Brasileiros de Cardiologia, 2001
PURPOSE: To evaluate 2 left ventricular mass index (LVMI) normality criteria for the prevalence of left ventricular geometric patterns in a hypertensive population ( HT ) . METHODS: 544 essential hypertensive patients, were evaluated by echocardiography,
Eduardo Cantoni Rosa, Valdir Ambrósio Moisés, Ricardo Cintra Sesso, Nárcia E. B. Kohlmann, Frida Liane Plavnik, Maria Teresa Zanella, Artur Beltrame Ribeiro, Osvaldo Kohlmann Júnior   +7 more
doaj   +1 more source