Results 151 to 160 of about 749,882 (394)
Advanced Science, EarlyView.Comparative cochlear transcriptomics of noise‐exposed bats (Miniopterus fuliginosus) and mice reveals bat‐specific protection mechanisms for noise‐induced hearing loss (NIHL), identifying Hras as a key hub regulator. Functional studies in mice show hair‐cell‐specific Hras overexpression significantly reduced hair‐cell damage and NIHL by activating the ...
Peng Chen +9 more
wiley +1 more source
Hologenomics Reveals Specialized Dietary Adaptations in the Mengla Snail‐Eating Snake
Advanced Science, EarlyView.Dietary adaptation studies from a holobiome perspective are scarce beyond mammals. This research reveals how genomic and microbial interactions drive dietary specialization in the Mengla snail‐eating snake, with evidence of gut symbiont convergence between reptiles and mammals.
Chaochao Yan +10 more
wiley +1 more source
Ascorbate-enhanced chondrogenesis of ATDC5 cells [PDF]
European Cells & Materials, 2006 The ATDC5 cell line exhibits the multistep chondrogenic differentiation observed during endochondral bone formation. However, it takes up to two months to complete the process of cell expansion, insulin addition to promote differentiation and further ...
F M Altaf +4 more
doaj
HAS THE CATHETER A PLACE IN THE TREATMENT OF CHRONIC PROSTATIC HYPERTROPHY? [PDF]
, 1905 PAUL THORNDIKE
openalex +1 more source
A Long Non-Coding RNA Defines an Epigenetic Checkpoint in Cardiac Hypertrophy
Nature Network Boston, 2016 Epigenetic reprogramming is a critical process of pathological gene induction during cardiac hypertrophy and remodeling, but the underlying regulatory mechanisms remain to be elucidated.
Zhihua Wang +22 more
semanticscholar +1 more source
Parabiosis, Assembloids, Organoids (PAO)
Advanced Science, EarlyView.This review evaluates parabiosis, organoids, and assembloids as complementary disease models spanning systemic, organ, and multi‐organ levels. It highlights their construction strategies, applications, and current limitations, while emphasizing their integration with frontier technologies such as artificial intelligence, organ‐on‐a‐chip, CRISPR, and ...
Yang Hong +5 more
wiley +1 more source
RPS27L Enhances Myogenesis and Muscle Mass by Targeting IGF1 Through Liquid‐Liquid Phase Separation
Advanced Science, EarlyView.Muscle‐specific RPS27L knock‐in mice exhibit increased body weight, muscle mass, and enhanced muscle regenerative capacity. RPS27L drives myogenesis by promoting myoblast proliferation, while inhibiting myogenic differentiation. Mechanistically, RPS27L targets IGF1 protein by liquid‐liquid phase separation through its N‐terminal intrinsically ...
Xiaoqin Liu +17 more
wiley +1 more source
Complementary Medicine Journal of Faculty of Nursing and Midwifery, 2022 Objective Consumption of pomegranate extract along with resistance training can improve the blood flow, resting metabolism and cause weight loss. However, their effect on body composition and weight control has not been studied.
Meysam Irani +2 more
doaj
Mechanical Stress Triggers Premature Senescence in Cardiac Fibroblasts
Advanced Science, EarlyView.Cellular senescence contributes to disease burden in cardiovascular disease (CVD) and aging, highlighting the need to understand its induction. In primary cardiac fibroblasts, reduced strain and increased frequency, mimicking CVD, elicit a distinct senescent phenotype compared to oxidative stress.
Stephanie E. Schneider +5 more
wiley +1 more source
A CASE of CONGENITAL HYPERTROPHY of the PYLORUS [PDF]
, 1898 Humphry Rolleston, L. B. Hayne
openalex +1 more source