Results 51 to 60 of about 486,688 (369)

Nuclei‐Specific Amygdala Enlargement Is Linked to Psychiatric Comorbidities in Drug‐Resistant Focal Epilepsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amygdala enlargement has been the subject of controversial studies regarding its significance in terms of pathogenicity both in epilepsy and in psychiatric comorbidities such as anxiety, depression, and post‐traumatic stress disorder.
Hélène Mourre   +15 more
wiley   +1 more source

Synthesis of standard 12-lead electrocardiograms using two dimensional generative adversarial network [PDF]

open access: yesarXiv, 2021
This paper proposes a two-dimensional (2D) bidirectional long short-term memory generative adversarial network (GAN) to produce synthetic standard 12-lead ECGs corresponding to four types of signals: left ventricular hypertrophy (LVH), left branch bundle block (LBBB), acute myocardial infarction (ACUTMI), and Normal.
arxiv  

Collagen type II suppresses articular chondrocyte hypertrophy and osteoarthritis progression by promoting integrin β1−SMAD1 interaction

open access: yesBone Research, 2019
Hypertrophic differentiation is not only the terminal process of endochondral ossification in the growth plate but is also an important pathological change in osteoarthritic cartilage.
Chengjie Lian   +13 more
semanticscholar   +1 more source

CAMTA in Cardiac Hypertrophy [PDF]

open access: yesCell, 2006
In this issue of Cell, the Calmodulin binding transcription activator 2 (CAMTA2), is shown by Song et al. (2006) to be an indispensable transcription coactivator for cardiac hypertrophy. CAMTA2 is activated by the dissociation of class II histone deacetylase 5 and promotes transcription of genes involved in cardiac hypertrophy through its interaction ...
Michael D. Schneider   +2 more
openaire   +3 more sources

Biologically‐Inspired Melt Electrowriting for the Generation of Highly Biomimetic Functional Myocardium

open access: yesAdvanced Functional Materials, EarlyView.
In this work, melt electrowriting is used to fabricate a 3D printed scaffold design that generates engineered cardiac tissues with in‐plane contraction, mimicking natural myocardium. It is shown that these tissues display advanced maturation and functionality.
Olalla Iglesias‐García   +23 more
wiley   +1 more source

Significance of MEF2C and RUNX3 Regulation for Endochondral Differentiation of Human Mesenchymal Progenitor Cells

open access: yesFrontiers in Cell and Developmental Biology, 2020
Guiding progenitor cell development between chondral versus endochondral pathways is still an unachieved task of cartilage neogenesis, and human mesenchymal progenitor cell (MPC) chondrogenesis is considered as a valuable model to better understand ...
Simon I. Dreher   +4 more
doaj   +1 more source

Anionic Citrate‐Based 3D‐Printed Scaffolds for Tunable and Sustained Orthobiologic Delivery to Enhance Tissue Regeneration

open access: yesAdvanced Functional Materials, EarlyView.
A potent anionic citric acid‐based 3D‐printed scaffold is developed for the sustained and controlled release of orthobiologics to enhance orthopedic therapeutic efficacy. Comprehensive in vivo studies demonstrated effective bone fusion and high safety at a low dose of BMP‐2 delivered by the system, establishing it as a promising platform for safe ...
Se‐Hwan Lee   +12 more
wiley   +1 more source

Self supervised convolutional kernel based handcrafted feature harmonization: Enhanced left ventricle hypertension disease phenotyping on echocardiography [PDF]

open access: yesarXiv, 2023
Radiomics, a medical imaging technique, extracts quantitative handcrafted features from images to predict diseases. Harmonization in those features ensures consistent feature extraction across various imaging devices and protocols. Methods for harmonization include standardized imaging protocols, statistical adjustments, and evaluating feature ...
arxiv  

Metabolic Remodeling Promotes Cardiac Hypertrophy by Directing Glucose to Aspartate Biosynthesis

open access: yesCirculation Research, 2019
Supplemental Digital Content is available in the text. Rationale: Hypertrophied hearts switch from mainly using fatty acids (FAs) to an increased reliance on glucose for energy production. It has been shown that preserving FA oxidation (FAO) prevents the
J. Ritterhoff   +9 more
semanticscholar   +1 more source

Prostatic Hypertrophy. [PDF]

open access: yesJAMA: The Journal of the American Medical Association, 1893
n ...
openaire   +2 more sources

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