Results 131 to 140 of about 71,655 (301)

Association between diabetes and in‐hospital outcomes in patients with metabolic dysfunction‐associated steatotic liver disease hospitalized for cardiovascular disease: A nationwide database study

Diabetic Medicine, Volume 43, Issue 5, May 2026.
In a nationwide cohort of 10,614 patients with metabolic dysfunction–associated steatotic liver disease (MASLD) hospitalized for cardiovascular disease (CVD), diabetes was present in 4550 patients (43%) and was independently associated with higher in‐hospital mortality and cardiovascular complications.
Soichi Komaki, Michikazu Nakai, Yunosuke Matsuura, Kinuko Yamamoto, Hiroki Tanaka, Yuri Komaki, Masashi Yamaguchi, Kohei Moribayashi, Takeshi Ideguchi, Hiroshi Kawakami, Toshihiro Tsuruda, Koichi Kaikita   +11 more
wiley   +1 more source

ChREBP‐β Exacerbates Renal Tubular Disorders Caused by Fructose via ATF4

The FASEB Journal, Volume 40, Issue 8, 30 April 2026.
Schematic diagram of the mechanism underlying fructose‐induced renal tubular injury via ChREBP‐β‐mediated disruption of endoplasmic reticulum and mitochondrial homeostasis. This diagram illustrates that fructose induces the transcriptional activation of ChREBP‐β, which subsequently triggers endoplasmic reticulum stress, disturbs inter‐organelle calcium
Ting Fang, Xinyu Yang, Xiaoqing Deng, Jingyi Wang, Ting Li, Hang Guo, Bei Sun, Liming Chen   +7 more
wiley   +1 more source

Pulmonary Function Decline in Very Early Diagnosis of Systemic Sclerosis: A Retrospective Longitudinal Single‐Center Study

ACR Open Rheumatology, Volume 8, Issue 4, April 2026.
Objective The very early diagnosis of systemic sclerosis (SSc; VEDOSS) criteria aim to identify patients at risk of evolving into SSc. The predictive value of diffusing capacity of the lungs for carbon monoxide (DLco) and forced vital capacity (FVC) remains poorly characterized. This study aimed to evaluate whether baseline pulmonary function test (PFT)
Eugenio Capparelli, Greta Pellegrino, Eleonora Zaccara, Giorgio Bonardi, Elisabetta Ricchiuti, Daniele Colombo, Maria Sole Chimenti, Paola Faggioli, Antonino Mazzone   +8 more
wiley   +1 more source

Associations of body mass index and remnant cholesterol with hyperuricemia in patients with hypertension

BMC Endocrine Disorders
Background There is a paucity of prior research on residual cholesterol (RC) and hyperuricemia, and it remains unclear whether body mass index (BMI) functions as a mediating factor between them or intensifies lipid metabolic dysregulation, thereby ...
Wei Zhou, Tao Wang, Lingjuan Zhu, Yumeng Shi, Chao Yu, Huihui Bao, Xiaoshu Cheng   +6 more
doaj   +1 more source

Association between hyperuricemia and all-cause mortality in people taken Statins: a retrospective cohort study

Frontiers in Pharmacology
BackgroundStatins are one of the most widely prescribed medicines in clinical practice. Their benefits have extended beyond cardiovascular applications to reduce serum uric acid levels.
Bin Zhu, Zijun He, Mingfen Wu, Jiping Huo, Zhigang Zhao, Wei Guo, Li Yang   +6 more
doaj   +1 more source

Towards a cure for gout: A two‑stage treat‐to‐target strategy from inflammation control to structural remission

Rheumatology &Autoimmunity, EarlyView.
Jiani Liu, Ziwen Xu, Wenxi Cui, Man Lu, Qingqing Zhang, Wenxia Lin, Shixian Chen, Weikai Lin, Guichuan Lai, Meng Li, Juan Li   +10 more
wiley   +1 more source

Biopharmaceuticals for Cancer Treatment: An Update

Cancer Medicine, Volume 15, Issue 4, April 2026.
ABSTRACT Cancer is one of the most debilitating diseases, causing profound physical and psychological impacts on patients. The global number of cancer patients has been steadily rising over the last few decades. The development of effective cancer therapies remains the primary focus in life science research, requiring a precise understanding of ...
Anupom Deb Nath, Yousuf Alam, Afsana Mustak Mim, Maksuda Akter, Mohammad Abbas Gani, Khondaker Muhammad Khairul Alam, Md. Nur Alam   +6 more
wiley   +1 more source

Higher Atherogenic Index of Plasma Is Associated with Hyperuricemia: A National Longitudinal Study

International Journal of Endocrinology
Background. The association between atherogenic index of plasma (AIP) and hyperuricemia remains indistinct. This study was aimed to examine the relationship between AIP and hyperuricemia among the middle-aged and the elderly Chinese population.
Feifei Xu, Chengyong Ma, Shouping Wang, Qin Li, Zhongwei Zhang, Min He   +5 more
doaj   +1 more source

Genetic Association Between Insulin Resistance And Total Cholesterol In Type 2 Diabetes Mellitus - A Preliminary Observation [PDF]

, 2005
We investigated the degree of genetic association between insulin resistance (IR) with type 2 diabetes mellitus (DM) and abnormalities in lipid metabolism in 42 patients.
Gunasekara Sudari Wijewickrama, Hettihewa Lukshmy Menik, Imendra Kotapola, Jayasinghe Sudheera Sammanthi, Palangasinghe Shalika, Weerarathna Thilak Priyantha   +5 more
core   +1 more source

Hypertensive Urgency and Pulmonary Infiltrates: A Report of Three Cases

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Hypertensive urgency is commonly attributed to medication nonadherence, progression of essential hypertension, or secondary causes. However, in some patients, no clear precipitating factor is identified, despite repeated evaluations and the absence of target organ damage. Subclinical inflammatory conditions have been hypothesized as potential,
Mónica Contreras‐Moreira
wiley   +1 more source