Results 111 to 120 of about 71,655 (301)

Farnesoid X receptor prevents hyperuricemia via activating ATP‐binding cassette subfamily G member 2

Rheumatology &Autoimmunity, EarlyView.
Farnesoid X receptor (FXR) activation reduces serum uric acid levels by upregulating the intestinal urate transporter ATP‐binding cassette subfamily G member 2 (ABCG2). These findings uncover a novel metabolic pathway for urate excretion and suggest that FXR agonists (e.g., obeticholic acid), represent a promising therapeutic strategy for the treatment
Rui Li, Guo Tang, Ye Yu, Guang‐Liang Chen, Liangjing Lu, Juan Wang   +5 more
wiley   +1 more source

Gout in pediatric renal transplant recipients [PDF]

, 2018
Clinical gout has rarely been described after pediatric renal transplantation (RTx), although asymptomatic hyperuricemia is common in these patients. We describe three male pediatric patients who presented with gouty arthritis 7-8.5 years following RTx ...
Goetschel, Philippe, Laube, Guido, Trück, Johannes, von Vigier, Rodo   +3 more
core  

Clinical correlation of nonalcoholic fatty liver disease in a Chinese taxi drivers population in Taiwan: Experience at a teaching hospital [PDF]

, 2011
Background To explore any gender-related differences in the prevalence of conditions-associated with non-alcoholic fatty liver disease (NAFLD) among Taiwanese taxi drivers in Taipei, Taiwan. Methods We studied 1635 healthy taxi drivers (1541 males and 94
Chiu Wei-Hsiu, Chang Tsung-Hung, Tung Tao-Hsin, Lin Tzu-Han, Shih Hui-Chuan, Chang Ming-Huei, Liu Jorn-Hon   +6 more
core   +1 more source

Longest survivor of pulmonary atresia with ventricular septal defect without surgical intervention

ESC Heart Failure, Volume 12, Issue 2, Page 1499-1507, April 2025.
Sang Zhou, Yu Wu, Guoran Li, Yongwen Qin, Man Qi, Zhitao Jin   +5 more
wiley   +1 more source

Association between serum urate, gout and chronic kidney disease: a scoping review of systematic reviews and meta-analyses

Journal of Rheumatic Diseases
Hyperuricemia is highly prevalent in patients with chronic kidney disease (CKD) due to reduced renal urate clearance, which leads to an increased incidence of gout in this population.
Yoon-Jeong Oh, Jung-Min Shin, Jin-Wuk Hur, Chang-Nam Son   +3 more
doaj   +1 more source

Uromodulin storage diseases: clinical aspects and mechanisms. [PDF]

, 2004
The recent discovery of mutations in the uromodulin gene (UMOD) in patients with medullary cystic kidney disease type 2 (MCKD2), familial juvenile hyperuricemic nephropathy (FJHN), and glomerulocystic kidney disease (GCKD) provides the opportunity for a ...
Agre, Antonio Amoroso, Attar, Auranen, Bachmann, Bates, Bingham, Bingham, Bleyer, Bleyer, Brater, Carson, Chambers, Christodoulou, Ciechanover, Claudia Izzi, Coe, Cox, Dahan, Dahan, Doroti Pirulli, Ellgaard, Emma, Enomoto, Feather, Francesco Scolari, Fukuoka, Gian Marco Ghiggeri, Gianluca Caridi, Giorgio Casari, Gokhale, Gresh, Gusmano, Hart, Hartl, Heptinstall, Hershko, Hession, Hildebrandt, Hildebrandt, Hildebrandt, Hou, Hoyer, Huang, Jovine, Kamatani, Kaufman, Kobayashi, Kotanko, Kroiss, Kudo, Leal-Pinto, Luca Rampoldi, Maesaka, Mattey, Mayrer, McQueen, Melnick, Miyake, Mo, Nauli, Oh, Olbrich, Ong, Orskov, Otto, Otto, Pahl, Pak, Parkkinen, Pennica, Prasadan, Rampoldi, Regina Tardanico, Resnick, Rezende-Lima, Sanders, Schroter, Scolari, Scolari, Serafini-Cessi, Sharp, Simon, Stiburkova, Stiburkova, Su, Taulman, Thomas, Torffvit, Turner, Wang, Wangsiripaisan, Wilson, Wolf, Worcester, Woronik, Wu, Ying, Yoder, Yu, Zager   +100 more
core   +1 more source

Radiation‐induced peroxide rupture and its temperature‐dependent repair probed by homogeneous X‐ray irradiation

Acta Crystallographica Section D, EarlyView.
This manuscript investigates the X‐ray‐induced radiolysis of the catalytic C5‐peroxide adduct in urate oxidase crystals, utilizing a top‐hat X‐ray beam to monitor peroxide occupancy across extensive dose series at both 100 K and room temperature. The study reveals a kinetic phase transition where the peroxide decays rapidly via zero‐order kinetics at ...
Symeon Koulas, Soi Bui, Julius B. Kirkegaard, Gleb Bourenkov, Roberto A. Steiner   +4 more
wiley   +1 more source

Neck Circumference, a Novel Indicator for Hyperuricemia

Frontiers in Physiology, 2017
Background: Waist circumference has been correlated with the risk of hyperuricemia. Whether neck circumference is also associated with hyperuricemia has not been assessed.
Jiajia Jiang, Jia Cui, Xinghua Yang, Anping Wang, Yiming Mu, Liguang Dong, Shuyu Wang, Herbert Gaisano, Jingtao Dou, Yan He, Yan He   +10 more
doaj   +1 more source

Hubungan Hiperurisemia, Obesitas Dan Riwayat Merokok Dengan Kejadian Hipertensi [PDF]

, 2013
Hypertension is a common clinical problem. Hyperuricemia, obesity, and smoking history are assumed to have a relationship with hypertension in adult.
Ahmadi, A. P. (Adhytya), Eso, A. (Amirudin), Hamra, M. Y. (M)   +2 more
core  

Recent finding and new technologies in nephrolithiasis: a review of the recent literature [PDF]

, 2013
This review summarizes recent literature on advances regarding renal and ureteral calculi, with particular focus in areas of recent advances in the overall field of urolithiasis.
Bove P, Finazzi Agrò E, Kim FJ, Miano R, Micali S, Rosa M, Usai P   +6 more
core   +1 more source