Results 91 to 100 of about 41,061 (196)

Chronic high‐altitude exposure and intracerebral hemorrhage: A novel perspective from the vascular‐immune‐neuronal network

Neuroprotection, EarlyView.
Long‐term chronic high‐altitude hypobaric hypoxia increases susceptibility to ICH, particularly among migrant populations lacking EPAS1/SENP1 adaptive genetic variants relative to high‐altitude indigenous residents. Persistent hypoxia initiates blood–brain barrier (BBB) breakdown, aberrant glial and immune activation, and progressive neuronal injury ...
Rongsu Huang, Linjie Wei, Mingxi Li, Bo Wu, Rongjian Ouyang, Gang Zhu, Yujie Chen   +6 more
wiley   +1 more source

Factors associated with hyperuricemia of all subjects.

, 2018
Factors associated with hyperuricemia of all subjects.
Jee-Fu Huang (292609), Tyng-Yuan Jang (4099975), Chia-Yen Dai (292610), Ching-I Huang (391259), Meng-Hsuan Hsieh (550259), Wan-Long Chuang (292615), Zu-Yau Lin (292611), Shinn-Cherng Chen (292612), Chung-Feng Huang (292606), Ming-Lung Yu (292600), Ming-Lun Yeh (349881)   +10 more
core   +1 more source

Prevalence of Hyperuricemia among People of Morang District of Nepal

Journal of Nobel Medical College, 2014
Hyperuricemia refers to an elevation in the serum uric acid concentration. The blood levels of uric acid are a function of the balance between the breakdown of purines & the rate of uric acid excretion.
Shrawan Kumar Yadav, Nirag Nepal, DilliRam Niroula   +2 more
doaj   +1 more source

Treatment of Severe Obstructive Sleep Apnea With a Domestic Implantable Hypoglossal Nerve Stimulator: A Case Report

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Implantable hypoglossal nerve stimulation (HNS) is an established neuromodulatory therapy for obstructive sleep apnea (OSA) in patients intolerant to continuous positive airway pressure (CPAP). However, no domestically developed HNS system has been clinically implemented in China to date.
Su‐Ru Liu, En‐Hui Zhou, Xin‐Yi Li, Hua‐Jun Xu, Jian Guan, Hong‐Liang Yi, Shan‐Kai Yin   +6 more
wiley   +1 more source

Association between organophosphate esters exposure and the prevalence of hyperuricemia in US adults from NHANES 2011–2016

Scientific Reports
Organophosphate esters (OPEs) exposure has potentially harmful effects on human health. However, the evidence between OPEs and hyperuricemia is insufficient. We aimed to assess the association between OPEs metabolites and the prevalence of hyperuricemia.
Qiong Huang, Wenbin Nan, Siqi Li, Baimei He, Xu Cai, Zhenyu Peng, Chenlu Wu   +6 more
doaj   +1 more source

Exogenous chemical exposures and metabolic disruptions in hyperuricemia: a multi-omics mediation study

Environment International
Background: Hyperuricemia has emerged as a significant public health concern. However, the relationship between hyperuricemia and both individual and mixed exogenous chemicals remains poorly understood, and the underlying mechanisms are still unclear ...
Yang Ouyang, Lvyun Sun, Di Yu, Qi Li, Shanshan Du, Xiaolin Wang, Mengyao Wang, Guowang Xu, Weimin Ye, Xinyu Liu   +9 more
doaj   +1 more source

Triangulating Evidence on Serum Uric Acid and Cancer Risk: Consistent Inverse Associations With Lung Cancer

Cancer Science, EarlyView.
Using both conventional observational and Mendelian randomization (MR) analyses in the same Japanese community‐dwelling population, the evidence consistently supported an inverse association between the serum uric acid level and lung cancer risk. ABSTRACT We examined the association between serum uric acid (UA) levels and cancer incidence through a ...
Takashi Matsunaga, Kenji Wakai, Takashi Tamura, Mako Nagayoshi, Rieko Okada, Itsuki Kageyama, Megumi Hara, Takuma Furukawa, Hiroaki Ikezaki, Yuji Matsumoto, Takeshi Nishiyama, Hiroko Nakagawa‐Senda, Chihaya Koriyama, Shiroh Tanoue, Naoyuki Takashima, Etsuko Ozaki, Katsuyuki Miura, Aya Kadota, Takeshi Watanabe, Masashi Ishizu, Kiyonori Kuriki, Masahiro Nakatochi, Yukihide Momozawa, Issei Imoto, Isao Oze, Keitaro Matsuo, the J‐MICC Study Group   +26 more
wiley   +1 more source

Prevalence and correlates of hyperuricemia in the middle-aged and older adults in China [PDF]

, 2018
Hyperuricemia, the physiological prerequisite for gout, is linked to the presence and severity of multiple comorbidities that affect longevity and well-being.
He Wang, Wang, H, Wei Xia, Xinlei Chang, Chang, X, Lin An, Peige Song, Wang, M, Song, P, Manli Wang, An, L, XIA, W   +11 more
core   +1 more source

Dyslipidaemia, Chronic Kidney Disease and Diabetes Mellitus: A Triple Threat to Cardiovascular Health

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Diabetes mellitus (DM) and chronic kidney disease (CKD) frequently coexist and together create a ‘triple threat’ with dyslipidaemia, enhancing the risk for cardiovascular morbidity and mortality. Diabetic kidney disease (DKD) leads to altered lipid metabolism through insulin resistance, inflammation and oxidative stress resulting in an ...
Ann S. Forrest, Priyanka Majety, Stéphanie B. Mayer, Om P. Ganda   +3 more
wiley   +1 more source

Converging Relationships of Obesity and Hyperuricemia with Special Reference to Metabolic Disorders and Plausible Therapeutic Implications

Diabetes, Metabolic Syndrome and Obesity, 2020
Min Gong, Song Wen, Thiquynhnga Nguyen, Chaoxun Wang, Jianlan Jin, Ligang Zhou Department of Endocrinology, Shanghai Pudong Hospital, Fudan University, Shanghai 201399, People’s Republic of ChinaCorrespondence: Ligang ZhouDepartment of ...
Gong M, Wen S, Nguyen T, Wang C, Jin J, Zhou L   +5 more
doaj