Results 31 to 40 of about 41,061 (196)

Hyperuricemia and gout increased the risk of long-term mortality in patients with heart failure: insights from the National Health and Nutrition Examination Survey

Journal of Translational Medicine, 2023
Background The prevalence of hyperuricemia, gout, and heart failure (HF) is on the rise, and these conditions often share similar risk factors. The present study aimed to evaluate the relationship among hyperuricemia, gout, HF, and all-cause mortality ...
Yingdong Han, Yu Cao, Xinxin Han, Hong Di, Yue Yin, Juan Wu, Yun Zhang, Xuejun Zeng   +7 more
doaj   +1 more source

Circ_0058051 Targeted miR-129-5P Regulates Autophagy-Related Gene ATG7 to Promote the Inflammation of Gout

Mediators of Inflammation
Gout is a common autoinflammatory disease that clinically manifests as recurrent joint redness, swelling, and pain, but the molecular mechanism of recurrent gouty inflammation remains unclear.
Jianwei Guo, Tianyi Lei, Yi Jiang, Peng Wang, Zeng Zhang, Xiang Yu, Guilin Jian, Quanbo Zhang, Yufeng Qing   +8 more
doaj   +1 more source

Advancing precision medicine in axial spondyloarthritis: insights from multi-omics approaches

Frontiers in Medicine
Axial Spondyloarthritis (axSpA) is a chronic inflammatory disease influenced by genetic, immune, metabolic, and environmental factors, significantly impacting patients’ quality of life.
Yuanpiao Ni, Yuanpiao Ni, Yuanpiao Ni, Quanbo Zhang, Quanbo Zhang, Xin Wu, Huji Xu, Yufeng Qing, Yufeng Qing   +8 more
doaj   +1 more source

Polymorphisms of the genes ABCG2, SLC22A12 and XDH and their relation with hyperuricemia and hypercholesterolemia in Mexican young adults [version 2; peer review: 2 approved]

F1000Research, 2021
Background: Hyperuricemia is a pathological condition associated with risk factors of cardiovascular disease. In this study, three genetic polymorphisms were genotyped as predisposing factors of hyperuricemia.
Juan Manuel Vargas-Morales, Martha Guevara-Cruz, Celia Aradillas-García, Lilia G. Noriega, Armando Tovar, Jorge Alejandro Alegría-Torres   +5 more
doaj   +1 more source

Health Care Use Among Patients Presenting to Emergency Department for Gout Flares in Ontario, Canada: A Population‐Based Health Systems Analysis

Arthritis Care &Research, EarlyView.
Objective We characterized emergency department (ED) gout visits and identified patient characteristics and health services patterns contributing to ED presentations. Methods We conducted a population‐based study of ED gout visits in Ontario, Canada, between 2014 and 2023.
Timothy S. H. Kwok, Samantha Morais, William K. Silverstein, Clare L. Atzema, Gregory Choy, Priyanka Chandratre, Ping Li, Jessica Widdifield   +7 more
wiley   +1 more source

Febuxostat for Hyperuricemia in Patients with Advanced Chronic Kidney Disease

, 2014
Febuxostat is a nonpurine xanthine oxidase (XO) inhibitor, which recently received marketing approval. However, information regarding the experience with this agent among advanced chronic kidney disease (CKD) patients is limited. In the current study, we
Daisuke Nagata, Osamu Iimura, Tetsu Akimoto, Yuko Watanabe, Chiharu Ito, Eiji Kusano, Sadao Tsunematsu, Yoshiyuki Morishita   +7 more
core   +1 more source

Association between oral health and hyperuricemia in Korean adults: Korea National Health and Nutrition Examination Survey 2016–2019 [PDF]

The Korean Journal of Internal Medicine
Background/Aims Hyperuricemia plays an essential role in the gout. Despite the clinical significance of hyperuricemia, a direct relationship between oral health and hyperuricemia has not been established.
Junyong Park, Minkook Son, Sung Won Lee, Won Tae Chung, Sang Yeob Lee   +4 more
doaj   +1 more source

Elevated Liver Enzymes Is Not an Impediment to Allopurinol Dose Escalation: An Observational Cohort Study

Arthritis Care &Research, EarlyView.
Objective Routine liver enzyme monitoring is advocated for while on allopurinol, but supporting guidance is lacking. We assessed the incidence and factors associated with elevated liver enzyme levels in patients with gout commenced on allopurinol. Methods One hundred and fifty patients with gout and normal baseline serum aminotransferases initiated on ...
May Shuen Tang, Qai Ven Yap, Peter Pak Moon Cheung, Amelia Santosa, Gim Gee Teng   +4 more
wiley   +1 more source

The association of gout flare resolution with physical activity and sleep: a prospective remote‐monitoring study

Arthritis Care &Research, Accepted Article.
Objectives This study aimed to determine whether gout flare resolution is associated with physical activity and sleep. These findings were intended to inform the future development of a definition for flare resolution. Methods Data from 81 participants with gout who experienced >1 flare during a 6‐month prospective observational study were included ...
Sarah Stewart, Boston Girven, Mia Clarke, Irene Zeng, Angelo Gaffo, Lisa K Stamp, N Lawrence Edwards, David Rice, Tania Ka'ai, Karl Rudolph, Julie Collis, Nicola Kayes, Nicola Dalbeth   +12 more
wiley   +1 more source

Research Progress on the Relationship between Dietary Patterns and Hyperuricemia

, 2022
As the final metabolite of purine metabolism, uric acid is critically associated with human health. The serum uric acid level is regulated by diet and the metabolic capacity of the human body. The impaired control of uric acid metabolism and excretion is
Tian Long, Liu, Liang, Liang Liu, Long, Tian   +3 more
core   +1 more source