Results 61 to 70 of about 71,655 (301)

Advancing precision medicine in axial spondyloarthritis: insights from multi-omics approaches

Frontiers in Medicine
Axial Spondyloarthritis (axSpA) is a chronic inflammatory disease influenced by genetic, immune, metabolic, and environmental factors, significantly impacting patients’ quality of life.
Yuanpiao Ni, Yuanpiao Ni, Yuanpiao Ni, Quanbo Zhang, Quanbo Zhang, Xin Wu, Huji Xu, Yufeng Qing, Yufeng Qing   +8 more
doaj   +1 more source

Punicalagin attenuates hyperuricemia via restoring hyperuricemia-induced renal and intestinal dysfunctions

Journal of Advanced Research
Graphical abstract Schematic diagram illustrated the action mechanisms through which PU reduced UA level in hyperuricemia mice by protecting the kidney and intestine. Schematic diagram created using Figdraw (www.figdraw.com).
Qing-qing Han, Qi-dong Ren, Xu Guo, Mohamed A. Farag, Yuhong Zhang, Mengqi Zhang, Ying‐ying Chen, Shu-tao Sun, Jin-Yue Sun, Ning Li, Chao Liu   +10 more
semanticscholar   +1 more source

Role of diet in hyperuricemia and gout.

Baillière's Best Practice & Research : Clinical Rheumatology, 2021
BACKGROUND Gout is the most common form of inflammatory arthritis, affecting 41 million adults worldwide. The global burden of gout has been increasing over the last three decades, yet its management remains suboptimal. The primary aim of this manuscript
A. Danve, S. Sehra, T. Neogi
semanticscholar   +1 more source

Retractions in Rheumatology: Trends, Causes, and Implications for Research Integrity

Arthritis Care &Research, EarlyView.
Objective We aimed to describe the trends and main reasons for study retraction in rheumatology literature. Methods We reviewed the Retraction Watch database to identify retracted articles in rheumatology. We recorded the main study characteristics, authors’ countries, reasons for retraction, time from publication to retraction, and trends over time ...
Anna Maria Vettori, Michele Iudici
wiley   +1 more source

Relationship between gout, hyperuricemia, and obesity—does central obesity play a significant role?—a study based on the NHANES database

Diabetology & Metabolic Syndrome
Our objective was to evaluate how various measures of obesity, such as body mass index(BMI), body roundness index(BRI), and weigh adjusted waist index(WWI), influence urate levels, prevalence of gout and to compare the disparities among these obesity ...
Tongjun Mao, Q. He, Junping Yang, Lanlan Jia, Guofei Xu   +4 more
semanticscholar   +1 more source

Hyperuricemia remodels the serum proteome toward a higher inflammatory state

iScience, 2023
Summary Gout is an autoinflammatory disease triggered by a complex innate immune response to MSU crystals and inflammatory triggers. While hyperuricemia is an obligatory risk factor for the development of gout, the majority of individuals with ...
Georgiana Cabău, O. Gaal, M. Badii, Valentin Nica, Andreea-Manuela Mirea, I. Hotea, C. Pamfil, R. A. Popp, M. Netea, Simona Rednic, T. Crișan, L. Joosten   +11 more
semanticscholar   +1 more source

Effects of causal beliefs about gout on public views about gout management: A randomized experimental study

Arthritis Care &Research, Accepted Article.
Objective Despite well‐described biological causes, the public views unhealthy lifestyle choices as the primary cause of gout. This study investigated how causal beliefs about gout influence the public's views about its management. Methods In a randomized study, 201 members of the public viewed one of two 2‐minute videos about gout.
Rachel Murdoch, Borislav Mihov, Anne Horne, Keith J. Petrie, Gregory D. Gamble, Lachlan Fleck, Nicola Dalbeth   +6 more
wiley   +1 more source

Is hyperuricemia an independent risk factor for new-onset chronic kidney disease?: a systematic review and meta-analysis based on observational cohort studies [PDF]

, 2014
This article discusses the role of interrogation in intelligence during the Second World War, and it focuses on the importance of culture in the collection of Human Intelligence in the European theatre of operation.
Ling Li, Chen Yang, Yuliang Zhao, Xiaoxi Zeng, Fang Liu, Ping Fu   +5 more
core   +5 more sources

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

Plasma aldosterone concentrations elevation in hypertensive patients: the dual impact on hyperuricemia and gout

Frontiers in Endocrinology
Background Prior research has highlighted the association between uric acid (UA) and the activation of the renin-angiotensin-aldosterone system (RAAS).
Shuaiwei Song, Xintian Cai, Junli Hu, Qing Zhu, Di Shen, Huimin Ma, Yingying Zhang, Rui Ma, Pan Zhou, Wenbo Yang, Jing Hong, Delian Zhang, Nanfang Li   +12 more
semanticscholar   +1 more source