Results 331 to 340 of about 119,001 (387)

Night‐Time Chronotherapy with Methylprednisolone Prevents an Acute Rejection in Pediatric Patients with Liver Transplantation: A Randomized Clinical Trial

open access: yesClinical Pharmacology &Therapeutics, Volume 118, Issue 2, Page 386-393, August 2025.
Concept of methylprednisolone chronotherapy to prevent acute rejections. While endogenous cortisol secretion rises in the early morning, the number of lymphocytes in the blood is higher at night, thus exhibiting an antiphase pattern to cortisol secretion. Therefore, compared with the daytime, the infiltration of lymphocytes into immune‐reactive tissues
Kentaro Ushijima   +11 more
wiley   +1 more source

Age and Sex Differences in Adverse Events Associated With Antipsychotics: An Analysis of the FDA Adverse Events Database

open access: yesInternational Journal of Geriatric Psychiatry, Volume 40, Issue 8, August 2025.
ABSTRACT Objectives While the risks of antipsychotics in older adults are well recognized, clinical trials often exclude frail older patients, have short follow‐up periods, and provide limited comparative data on specific drugs. This study aimed to explore age‐related differences in the adverse effects of six commonly prescribed antipsychotics using a ...
Tabea Ramin   +4 more
wiley   +1 more source

Modeling drug retention as memory effects in obese patients using fractional and augmented models. [PDF]

open access: yesSci Rep
Ynineb AR   +9 more
europepmc   +1 more source

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