Results 41 to 50 of about 27,102 (328)

Remimazolam, a novel drug, for safe and effective endoscopic sedation [PDF]

open access: yesClinical Endoscopy
Remimazolam is a novel benzodiazepine with unique pharmacokinetic and pharmacodynamic properties, making it an ideal candidate for sedation during endoscopic procedures.
Jae Min Lee   +4 more
doaj   +1 more source

Impact of the use of illicit and licit substances and anxiety disorders on the academic performance of medical students: a pilot study

open access: yesBMC Medical Education, 2022
Background Medical students have a considerable prevalence of anxiety and substance use disorders. Our aim was to assess the presence of anxiety disorders and the use of alcohol and licit and illicit substances, and their influence on the academic ...
Pedro Marques Ferreira   +2 more
doaj   +1 more source

Psychoactive prescription drug use and misuse in patients on opioid agonist treatment

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims To identify the patterns and trends in prescription drug use and misuse in patients on opioid agonist treatment. Methods We used data from the OPPIDUM programme, which collects data from patients attending substance abuse treatment facilities. Data collected include use of psychoactive prescription drugs in the past week.
Thomas Soeiro   +5 more
wiley   +1 more source

Efficacy of midazolam as oral premedication in children in comparison to triclofos sodium

open access: yesIndian Journal of Anaesthesia, 2016
Background and Aims: The perioperative behavioural studies demonstrate that children are at greater risk of experiencing turbulent anaesthetic induction and adverse behavioural sequelae.
Kolathu Parambil Radhika   +2 more
doaj   +1 more source

Gambling disorder-related illegal acts: Regression model of associated factors [PDF]

open access: yes, 2016
Gambling disorder-related illegal acts (GDRIA) are often crucial events for gamblers and/or their entourage. This study was designed to determine the predictive factors of GDRIA.
Challet-Bouju, Gaëlle   +11 more
core   +3 more sources

The persistence of chronic opioid use in patients with inflammatory bowel disease—A nationwide cohort study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Pain is common in patients with Crohn's disease (CD) and ulcerative colitis (UC), and a substantial proportion develop chronic opioid use (COU). We examined the persistence of COU over time and identified factors predicting persistent use. Methods This nationwide Danish cohort study included patients with an initial period of COU (definition: ≥3 ...
Bente Mertz Nørgård   +6 more
wiley   +1 more source

Hypnotics use in children 0–18 months: moderate agreement between mother-reported survey data and prescription registry data

open access: yesJournal of Pharmaceutical Policy and Practice, 2017
Background Different methods in pharmacoepidemiology can be used to study hypnotic use in children. But neither questionnaire-based data nor prescription records can be considered a “gold standard”.
Ingvild Holdø   +7 more
doaj   +1 more source

Combined use of selective serotonin reuptake inhibitors and sedatives/hypnotics during pregnancy: risk of relatively severe congenital malformations or cardiac defects. A register study

open access: yesBMJ Open, 2013
Objectives To investigate the proposed synergistic teratogenic effect of use of selective serotonin receptor inhibitors (SSRI) together with sedatives or hypnotics, primarily benzodiazepines, during pregnancy.
M. Reis, B. Källén
semanticscholar   +1 more source

Hypnotic doses of fazamorexant induced less impairment on balance and cognition than zolpidem in healthy younger and elderly individualse

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Fazamorexant is a dual orexin receptor antagonist being developed for the treatment of insomnia. This study aims to determine the dose‐exposure‐response relationship of single‐dose fazamorexant vs. zolpidem in young adult and elderly healthy Chinese volunteers. Methods This single‐centre, randomized, double‐blind, double‐dummy, placebo‐ and active‐
Chen Xia   +3 more
wiley   +1 more source

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