Results 31 to 40 of about 12,566 (201)

Hypnotics use in children 0–18 months: moderate agreement between mother-reported survey data and prescription registry data

Journal of Pharmaceutical Policy and Practice, 2017
Background Different methods in pharmacoepidemiology can be used to study hypnotic use in children. But neither questionnaire-based data nor prescription records can be considered a “gold standard”.
Ingvild Holdø, Jørgen G. Bramness, Marte Handal, Leila Torgersen, Ted Reichborn-Kjennerud, Eivind Ystrøm, Hedvig Nordeng, Svetlana Skurtveit   +7 more
doaj   +1 more source

Concomitant inpatient prescribing of strong opioids with sedatives: Associations with comorbid conditions

Pharmacology Research & Perspectives, 2021
Co‐prescribing of opioids and sedatives is a known risk factor for opioid‐induced ventilatory impairment (OIVI). Prevalence data for sedative and opioid co‐prescription in inpatients in Australia are unknown. Our objective was to determine the prevalence
Ray J. Li, Gillian E. Caughey, Sepehr Shakib   +2 more
doaj   +1 more source

Effects of dexmedetomidine in non-operating room anesthesia in adults: a systematic review with meta-analysis

Brazilian Journal of Anesthesiology, 2023
Background: Dexmedetomidine (DEX) is an α2-adrenergic receptor agonist used for its sedative, analgesic, and anxiolytic effects. Non-Operating Room Anesthesia (NORA) is a modality of anesthesia that can be done under general anesthesia or procedural ...
Francisca Jerónimo Fonseca, Leonardo Ferreira, Ana Lídia Rouxinol-Dias, Joana Mourão   +3 more
doaj   +1 more source

Plasma and breast milk pharmacokinetics of suvorexant in healthy lactating women

British Journal of Clinical Pharmacology, EarlyView.
Aim This paper aims to evaluate the plasma and breast milk pharmacokinetics of suvorexant, an orexin receptor antagonist used to treat insomnia at a maximum dose of 20 mg, in healthy lactating women. Methods The paper reports on an open‐label Phase 1 study in 12 healthy lactating women.
Jacqueline McCrea, Andrew Litovsky, Prachi Wickremasingha, Nairita Ghosal, Brad Roadcap, Robert Valesky, Robin Lee, Leea D. Reed, Ming Wang, Wei Fang, Rebecca Wrishko   +10 more
wiley   +1 more source

Comparison of Dexmedetomidine and Midazolam as Co-induction Agents to Propofol for Proseal Laryngeal Mask Airway Insertion: A Randomised Control Trial [PDF]

Journal of Clinical and Diagnostic Research
Introduction: The Laryngeal Mask Airway (LMA) is a supraglottic device designed to secure the airway during minor to moderate surgical procedures. Second-generation LMAs, such as the ProSeal LMA (PLMA), offer enhanced safety features, including a ...
Anbuselvi Anoumandane, Vasanthakumar Murugesan, Sripriyanka Rajendran, Saranya Mandharan, Selvamani Subramanian   +4 more
doaj   +1 more source

Incident low‐dose quetiapine use in adults newly diagnosed with depression in primary care: A nationwide register‐based study

British Journal of Clinical Pharmacology, EarlyView.
Aims This study aimed to investigate the incidence of low‐dose quetiapine initiation and associated factors in adults newly diagnosed with depression in primary care. Methods We obtained medication dispensing records, primary and secondary care diagnoses and employment status for antipsychotic‐naïve individuals aged 16–65 newly diagnosed with ...
Laura Purra, Heidi Taipale, Miia Tiihonen, Markku Lähteenvuo, Jari Tiihonen, Aleksi Hamina   +5 more
wiley   +1 more source

Monitored anesthesia care with dexmedetomidine in transfemoral percutaneous trans-catheter aortic valve implantation: two cases report [PDF]

Korean Journal of Anesthesiology, 2014
Percutaneous trans-catheter aortic valve implantation (TAVI) is recommended for inoperable patients with severe aortic stenosis at high risk for conventional aortic valve replacement. Originally, TAVI was mostly performed under general anesthesia.
Hee-Sun Park, Kyung-Mi Kim, Kyoung-Woon Joung, In-Cheol Choi, Ji-Yeon Sim   +4 more
doaj   +1 more source

Histamine and the mechanisms of nausea and vomiting: Translating the uncertain pharmacology of cyclizine

British Journal of Clinical Pharmacology, EarlyView.
Abstract Cyclizine is a long‐established, short‐acting drug, registered for preventing motion sickness, post‐operative nausea and vomiting (PONV) and ‘vomiting of known cause’. The latter is not defined but may include pregnancy and patients receiving palliative care, historically accepted without large, controlled trials.
Gareth J. Sanger, Paul L. R. Andrews
wiley   +1 more source

Dose‐related propofol resistance in COVID‐19 patients: Altered drug plasma levels, mechanistic insights from neuronal‐derived extracellular vesicles and miRNA analysis

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Critical care for COVID‐19 patients presents unique challenges, particularly in sedation management. Patients demonstrate notable dose‐related resistance to propofol, potentially due to complex pharmacokinetic alterations. Emerging evidence suggests that plasma extracellular vesicle‐associated miRNA represents valuable predictive ...
Debora Curci, Carlotta Bidoli, Marco Gerdol, Charisse Winston, Robert A. Rissman, Giuliana Decorti, Antonella Fabretto, Andrea Taddio, Gabriele Stocco, Erik Roman‐Pognuz, Marianna Lucafò   +10 more
wiley   +1 more source

Criminal Poisoning: A Hospital-Based Survey in an Academic Center of Iran

International Journal of Medical Toxicology and Forensic Medicine, 2021
Background: One of the most common medical emergencies worldwide is deliberate or accidental poisoning. The ever-increasing consumption of toxins and fatal drugs is getting more critical by the time.
Maryam Salari Moghaddam, Mitra Rahimi
doaj