Results 81 to 90 of about 25,584 (365)

Unveiling the Therapeutic Potential of Atractylis aristata Batt. Aqueous Extract: Anti‐inflammatory, Antioxidant, Antibacterial, Sedative Activities & Phytochemical Profiling

ChemistryOpen, EarlyView.
This study evaluates the pharmacological properties of the aqueous extract of Atractylis aristata, focusing on its antioxidant, anti‐inflammatory, antibacterial, and sedative activities. Phytochemical analysis identifies bioactive compounds, while in vitro and in vivo tests demonstrate its therapeutic potential in addressing oxidative stress ...
Asma Abid, Nourelhouda Mekhadmi, Randa Mlik, Assia Bentahar, Kamilia Bireche, Bariza Frih, Walid Boussebaa, Aicha Mouane, Nezar Cherrada, Ana Sanches Silva, Messaouda Dekmouche, Lazhar Bechki, Khalid Mashay Al‐Anazi, Mohammad Abul Farah, Ahmad Ali   +14 more
wiley   +1 more source

Evaluation of the Sedative Activity of Naringenin: In Vivo Study with Pharmacokinetics and Molecular Docking Insights

ChemistryOpen, EarlyView.
The study investigates the sedative potential of naringenin (NAR) through in vivo and in silico approaches. NAR significantly enhances sleep duration and reduces latency in mice, especially when combined with diazepam. Molecular docking shows strong binding to GABAA receptors, suggesting a GABAergic mechanism.
Dipu Bishwas, Md. Shimul Bhuia, Salehin Sheikh, Mohammed Alfaifi, Abdul Malik, Nikhat J. Siddiqui, Divya Jain, Mehedi Hasan Bappi, Muhammad Torequl Islam   +8 more
wiley   +1 more source

Variables Influencing the Depth of Conscious Sedation in Plastic Surgery: A Prospective Study

Archives of Plastic Surgery, 2017
Background Conscious sedation has been widely utilized in plastic surgery. However, inadequate research has been published evaluating adequate drug dosage and depth of sedation.
Hyeonjung Yeo, Wonwoo Kim, Hyochun Park, Hoonnam Kim   +3 more
doaj   +1 more source

Fall Risk Increasing Drugs: The Effect on Injuries of the Frail Elderly Estimated from Administrative Data [PDF]

, 2011
Society benefits on a large scale from improved medical care and pharmaceuticals. The prescription of pharmaceuticals, however, also carries risks such as the possibility of an increased risk of falls, which may lead to severe injuries and increased ...
Ahrens, Susanne, Bauer, Thomas K., Lindenbaum, Katharina, Linder, Roland, Stroka, Magdalena A., Verheyen, Frank   +5 more
core  

Objective short sleep duration is associated with elevated blood pressure in depression: The autonomic nerve dysfunction effect

Sleep Research, EarlyView.
Abstract The relationship between sleep disturbance, autonomic nerve dysfunction, and blood pressure in patients with major depressive disorder (MDD) was unclear. We studied 66 patients with MDD and 66 age‐matched and sex‐matched controls. Objective and subjective sleep were assessed using the polysomnography and Pittsburgh Sleep Quality Index ...
Baixin Chen, Wenli Ban, Yanyuan Dai, Le Chen, Jun Wu, Dandan Zheng, Jiansheng Zhang, Yun Li   +7 more
wiley   +1 more source

Rectal Thiopental versus Intramuscular Ketamine in Pediatric Procedural Sedation and Analgesia; a Randomized Clinical Trial

Emergency, 2015
Introduction: Physicians frequently deal with procedures which require sedation of pediatric patients. Laceration repair is one of them. No study has been performed regarding the comparison between induction of sedation with sodium thiopental and ...
Reza Azizkhani, Mehrdad Esmailian, Azadeh shojaei, Keihan Golshani   +3 more
doaj  

Factors associated with high‐dose antipsychotic prescriptions in outpatients with schizophrenia: An analysis of claims data from a Japanese prefecture

Neuropsychopharmacology Reports, 2020
Background Antipsychotics are commonly prescribed in high doses in combination with multiple psychotropic drugs. This study focused on the high‐dose antipsychotic prescriptions in patients with schizophrenia, while aiming to identify their associations ...
Tatsuichiro Takahashi, Tetsuya Otsubo, Susumu Kunisawa, Noriko Sasaki, Yuichi Imanaka   +4 more
doaj   +1 more source

Alvásszabályozás és hipnotikumok: a benzodiazepin-receptor agonisták hatásai [PDF]

, 2006
As binding sites of the alpha-amino butyric acid receptor complexes benzodiazepine-receptors offer a possibility to enhance hyperpolarization-based inhibition by allosteric modulation.
Bódizs, Róbert
core  

Developing a Respiratory Depression Scorecard for Capnography Monitoring [PDF]

, 2013
Pulse oximetry is the most common way to measure a patient’s respiratory status in the hospital setting; however, capnography monitoring is a more accurate and sensitive technique which can more comprehensively measure respiratory function.
Katie Felhofer, Pharm.D.
core   +3 more sources

Efficacy and mechanisms of action of Shangxia Liangji formula in the treatment of insomnia

Sleep Research, EarlyView.
ABSTRACT Aims Shangxia Liangji formula (SXLJF) is a traditional Chinese medicine formula used clinically for the treatment of insomnia. However, the exact mechanism of SXLJF remains unclear. Methods and Results A mouse insomnia model was established by intraperitoneal injection of p‐chlorophenylalanine. Control, model, low/medium/high‐dose SXLJF (9.26,
Feng‐Ling Xiao, Xia‐Jie Quan, Lin Zuo, Jia‐Hui Gao, Xiong‐Ying Ji, Can Wang, Ping Zhang, Bo Ouyang   +7 more
wiley   +1 more source