Results 91 to 100 of about 11,769 (205)

Evaluating Anesthetics for Improving Scientific Research and Welfare Using Larval Zebrafish

Comprehensive Physiology, Volume 16, Issue 3, June 2026.
Using physiological and behavioral assays, we quantified the effectiveness and appropriateness of six commonly used fish anesthetics on zebrafish embryos. Different anesthetics performed better under different contexts. Figure prepared using BioRender.com.
Sylvia Dimitriadou, Mhairi Miller, Ali Pilehvar, Lynne U. Sneddon, Jessica L. Bamsey, Damilola Hogan‐Bassey, Maciej Trznadel, Jonathan S. Ball, Aya Takesono, Courtney Hillman, Hannah Rickard, Grace Popplewell, Jenna Corcoran, Tetsuhiro Kudoh, Charles R. Tyler, Matthew J. Winter   +15 more
wiley   +1 more source

Trends in Hospital Admissions for Psychoactive Substance Intoxication Among Children, Adolescents, and Young Adults in Slovenia, 2013-2023. [PDF]

J Clin Med
Lovrecic B, Simon MR, Lovrecic M.
europepmc   +1 more source

Gallic Acid‐Mediated Enhancement of Diazepam‐Induced Sedation via GABAA Receptor Modulation: In Vivo and In Silico Evaluation

Food Science &Nutrition, Volume 14, Issue 6, June 2026.
Gallic acid (GA) dose‐dependently reduced sleep latency and prolonged sleep duration in thiopental sodium‐induced mice, with synergistic effects when combined with diazepam. Molecular docking revealed GA's higher binding affinity (−9.8 kcal/mol) to GABAA receptor (α1 and β2 subunits) than diazepam (−8.4 kcal/mol), suggesting GABAergic potential ...
Noshin Tasnim Yana, Anike Chakrabarty, Chinmoy Kumar Saha, Nikhat Jamal Siddiqi, Norah Alnazhan, Md. Sakib Al Hasan, Feroz Khan Nun, Imam Hossen Rakib, Md. Nasimul Haque Shipon, Emon Mia, Md Asaduzzaman Jony, Ali Mohamod Wasaf Hasan, Muhammad Torequl Islam, Azmat Ali Khan   +13 more
wiley   +1 more source

Who misuses sedatives for sleep? Evidence from a nationally representative US sample. [PDF]

Sleep Med
Tam K, Sheehan C, Bjorklund E, Milani SA.   +3 more
europepmc   +1 more source

KREO Prevents CUMS‐Induced Depressive‐Like Behavior via Modulation of the BDNF Signaling Pathway

Food Science &Nutrition, Volume 14, Issue 6, June 2026.
This study showed that Chinese Kushui Rose Essential Oil (KREO) can alleviate depressive symptoms, increase voluntary activity, and enhance exploratory behavior in mice induced with chronic unpredictable mild stress (CUMS) by elevating serotonin (5‐HT) levels and reducing hyperactivity of the hypothalamic–pituitary–adrenal (HPA) axis.
Yanni Wang, Zhaorong Yue, Manjie Xu, Wenjun Xu, Weizhong Zhang, Xiaolong Li, Qinghong Liu, Kailong Guan, Zewen Zhang, Yang Li, Xin Wang, Hongyu Li   +11 more
wiley   +1 more source

Changes in psychotropic medication prescription patterns during the COVID-19 pandemic among Japanese children, adolescents and young adults: interrupted time-series study using a national claims database. [PDF]

BJPsych Open
Huang W, Matsui H, Sasabuchi Y, Yasunaga H.   +3 more
europepmc   +1 more source

Predicting Serious Adverse Events, Medication Abuse, Misuse, and Risk of Dependence for Medications with High Dependence Potential: Role of Patient-Reported Factors and Machine Learning Approach. [PDF]

Healthcare (Basel)
Kim Y, Sohn YJ, Yoo JY, Kim M, Kim S, Choi YJ.   +5 more
europepmc   +1 more source

Unraveling Inflammatory Pain: A Narrative Review of Molecular Pathways and Multidisciplinary Treatments

Health Science Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Background Inflammatory pain is a widespread global health concern arising from complex molecular pathways triggered by a consequence of tissue damage and immune activation. It significantly impacts quality of life and functional outcomes, necessitating a comprehensive understanding of underlying mechanisms and multidisciplinary approaches for
Fatma Mohamed Elmansy, Mohamed Goda Elbqry, Saddam Ahmed Al‐Ahdal, Fatima S. O. Ashmieg, Patience Osose Nasir, Nasiru Mohammed Abdullahi, Mohammed Nader Shalaby   +6 more
wiley   +1 more source

A whole population-based cohort study of the trajectory of the prevalence and the incidence of mental illness, challenging behaviour, and psychotropic medication prescribing in adults with intellectual disabilities in the Czech Republic between 2010 and 2022. [PDF]

BMC Psychiatry
Deb S, Jarkovský J, Melicharová H, Holub D, Limbu B, Třešňák P.   +5 more
europepmc   +1 more source

Acupuncture alters cortical and corticomuscular functional connectivity in stroke patients with motor dysfunction

Journal of Intelligent Medicine, Volume 3, Issue 2, Page 84-96, June 2026.
Abstract Stroke is a leading cause of global mortality and disability, often resulting in severe motor dysfunction. Acupuncture has shown promise in stroke rehabilitation, but its neural mechanisms remain unclear. This study investigated the immediate effects of acupuncture at GV26, PC6, and SP6 on cortical and corticomuscular functional connectivity ...
Rui Xu, Siheng Chen, Zhongxiang Zhang, Jin Yang   +3 more
wiley   +1 more source