Results 81 to 90 of about 12,153 (246)

Substitution Patterns After Discontinuation of CNS‐Active Medications in Older Adults in Primary Care

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Background Little is known about substitution of alternative medications in the context of deprescribing. The objectives were to: (1) determine the frequency of medication substitutions among those who discontinued a central nervous system (CNS)‐active medication, and (2) characterize substitutions as potentially inappropriate (as per the 2023
Shelly L. Gray, Annalisa V. Piccorelli, Laura A. Hart, Andrea J. Cook, Brian D. Williamson, Benjamin H. Balderson, Elizabeth A. Phelan   +6 more
wiley   +1 more source

Prevalence of Psychotropic Use and Psychotropic Polypharmacy in a Finnish National Cohort of Persons With Intellectual Disabilities

Journal of Intellectual Disability Research, EarlyView.
ABSTRACT Background Psychotropic use and psychotropic polypharmacy are common in people with intellectual disabilities, but representative population‐based studies on this topic are scarce. We evaluated the prevalence of psychotropic use and psychotropic polypharmacy in a Finnish nationwide cohort of people with intellectual disabilities aged 0–97 ...
Ville Virtanen, Leena Saastamoinen, Maria Arvio, Hannu T. Vesala, Sonja Miettinen, Antti Teittinen, Anna‐Maija Tolppanen   +6 more
wiley   +1 more source

Effect of Lemborexant‐Based Sleep Medication Formulary on Benzodiazepine Reduction and Clinical Outcomes: A Single‐Center Retrospective Study

Neuropsychopharmacology Reports
Benzodiazepine and non‐benzodiazepine hypnotics (Z‐drugs) are known risk factors for adverse events, including delirium and falls. Although formularies are intended to promote appropriate prescribing, few comprehensive studies have assessed their ...
Shunya Aoki, Katsutoshi Takada, Tatsuru Sugama, Mitsugi Kimiwada, Tatsuya Hoshino, Kaori Koike, Hirokazu Akada, Takahisa Saiga, Shigeki Sato, Ryosuke Shinkai, Yukihiro Shibata, Takashi Tomita   +11 more
doaj   +1 more source

Understanding Risks in the Care of People With Dementia in Acute Hospital Settings: Definitions, Types and Management Strategies—A Scoping Review

Journal of Clinical Nursing, EarlyView.
ABSTRACT Aims This scoping review explores how risk is defined, managed and mitigated in the care of people with dementia in acute hospital settings. Methods This scoping review followed Arksesy and O'Malley's five‐stage framework (2005) and was guided by the Joanna Briggs Institute methodology.
Ashitha Bhaskaran, Kate Irving, Eileen Courtney, Bert Gordijn, Marie Cantwell   +4 more
wiley   +1 more source

Insomnia and Risk of Tooth Wear and Fracture: Evidence From a Nationwide Population‐Based Cohort

Journal of Oral Rehabilitation, EarlyView.
In this nationwide population‐based cohort study, insomnia was associated with increased risks of tooth wear and tooth fracture. These findings suggest that insomnia may have clinically relevant implications for oral health. ABSTRACT Background Insomnia is associated with various systemic conditions; however, its relationship with structural dental ...
Heon‐Young Kim, Nahyun Kim, Jung‐Hyun Park, Gwang Hyun Leem, Hyo‐Jung Lee, Sooyeon Nam, Heeyeon Kim, Sun‐Jong Kim, Jin‐Woo Kim   +8 more
wiley   +1 more source

Development of the Sleeping Pills Receptivity and Involuntariness Scale-6 (SPRIS-6) to Assess Acceptance of Hypnotics Use

Nature and Science of Sleep
Seockhoon Chung,1,2 Mohd. Ashik Shahrier3 1Department of Psychiatry, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea; 2Life Care Center for Cancer Patients, Asan Medical Center Cancer Institute, Asan Medical Center,
Chung S, Shahrier MA
doaj  

Opioid Prescribing for Noncancer Patients—Issues of Drug Therapy Safety: Results from a German Study Based on Routine Data

Pharmacoepidemiology
Opioids are highly effective drugs but need close monitoring to avoid harm to patients. The aim of this study was to analyze how guideline recommendations are met for (i) the avoidance of the concomitant use of anxiolytics, hypnotics, or sedatives; (ii ...
Veronika Lappe, Daniel Grandt, Ursula Marschall, Ingrid Schubert   +3 more
doaj   +1 more source

Chronic insomnia, REM sleep instability and emotional dysregulation: A pathway to anxiety and depression?

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary The world‐wide prevalence of insomnia disorder reaches up to 10% of the adult population. Women are more often afflicted than men, and insomnia disorder is a risk factor for somatic and mental illness, especially depression and anxiety disorders.
Dieter Riemann, Raphael J. Dressle, Fee Benz, Kai Spiegelhalder, Anna F. Johann, Christoph Nissen, Elisabeth Hertenstein, Chiara Baglioni, Laura Palagini, Lukas Krone, Michael L. Perlis, Katharina Domschke, Mathias Berger, Bernd Feige   +13 more
wiley   +1 more source

Parasomnias and sleep‐related movement disorders induced by drugs in the adult population: a review about iatrogenic medication effects

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Parasomnias and sleep‐related movement disorders (SRMD) are major causes of sleep disorders and may be drug induced. The objective of this study was to conduct a systematic review of the literature to examine the association between drug use and the occurrence of parasomnias and SRMD.
Sylvain Dumont, Vanessa Bloch, Agnès Lillo‐Lelouet, Christine Le Beller, Pierre A. Geoffroy, Marc Veyrier   +5 more
wiley   +1 more source

Respiratory safety of lemborexant in adult and elderly subjects with moderate‐to‐severe chronic obstructive pulmonary disease

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Lemborexant 10 mg, a dual orexin‐receptor antagonist (DORA), did not elicit respiratory depressant effects, as measured by peripheral oxygen saturation (SpO2) or apnea–hypopnea index (AHI), in subjects with moderate‐to‐severe chronic obstructive pulmonary disease (COPD).
Jocelyn Y. Cheng, Daniel Lorch, Nancy Hall, Margaret Moline   +3 more
wiley   +1 more source