Results 101 to 110 of about 12,153 (246)

Understanding and reducing the prescription of hypnotics and sedatives at the interface of hospital care and general practice: a protocol for a mixed-methods study. [PDF]

BMJ Open, 2016
Heinemann S, Weiß V, Straube K, Nau R, Grimmsmann T, Himmel W, Hummers-Pradier E.   +6 more
europepmc   +1 more source

How Mental Concepts Shape Sleep: Introducing the Mental Concept Reactivation Hypothesis of Sleep

Journal of Sleep Research, EarlyView.
ABSTRACT Sleep problems affect a substantial proportion of individuals, and negative thoughts, rumination, and worry are considered key factors underlying persistence and severity. While extensive research has examined how these states disrupt sleep before falling asleep, much less is known about how mental concepts, including thoughts, expectations ...
Anna Zoé Wick, Björn Rasch
wiley   +1 more source

Lost in the System: Identifying Gaps in Adolescent Insomnia Care Using Nationwide Claims Data and a Healthcare Professional Survey

Journal of Sleep Research, EarlyView.
ABSTRACT Adolescent insomnia is common, persistent and impairing, yet little is known about how and where young people with sleep difficulties are identified and treated in regular care. Recent calls to prioritise sleep health as a public health imperative underscore the need to understand diagnostic and treatment pathways for those affected.
Leonie Franziska Maurer, Johanna Schulze, Alfred Wiater, Angelika Schlarb, Laurin Rötzer, Alexander Prehn‐Kristensen   +5 more
wiley   +1 more source

Changes in Nighttime Sleep Duration and Their Association With Cognitive Decline and Dementia Risk

Journal of Sleep Research, EarlyView.
ABSTRACT This study investigates changes in nighttime sleep duration in relation to cognitive decline and risk of incident dementia. A total of 3057 participants from the Swedish population study ‘Good Aging in Skåne’ (Mage = 68.4) with normal baseline sleep duration (6–8 h) were followed up to 20 years (Myears = 8.39). Self‐reported change was defined
Marieclaire Overton, Sölve Elmståhl, Rani Basna   +2 more
wiley   +1 more source

Does Hypoxic Burden Better Explain Sex Differences in Functional Impairments Than Apnoea‐Hypopnoea Index in Obstructive Sleep Apnoea?

Journal of Sleep Research, EarlyView.
ABSTRACT Women with obstructive sleep apnoea (OSA) report more severe functional impairments than men, despite lower apnoea‐hypopnoea index (AHI) values. This raises questions about the adequacy of AHI for capturing OSA severity. We explored sex differences in functional outcomes in OSA patients and examined whether AHI or hypoxic burden (HB) better ...
Urvashi Nanda, Yu Sun Bin, Philip de Chazal, Andrew S. L. Chan, Amanda Piper, Kristina Kairaitis, Peter A. Cistulli, Brendon J. Yee, on behalf of the Sydney Sleep Biobank Investigators, Peter Cistulli, Philip de Chazal, Yu Sun Bin, Lu Fu, Benjamin Tong, Glenn Stewart, Gary Cohen, Andrew S. L. Chan, Anna Mohammadieh, John Wheatley, Kristina Kairaitis, Stephen Lambert, Tracey Burns, Brendon Yee, Amanda Piper, Kerri Melehan, Amy Jackson, Gislaine Gauthier   +26 more
wiley   +1 more source

Targeting Orexin 2 Receptors in Idiopathic Hypersomnia and Narcolepsy: A Randomised Phase 1b Proof‐Of‐Concept Study of Alixorexton

Journal of Sleep Research, EarlyView.
Orexin 2 receptor agonists have demonstrated that targeting the orexin system may address symptoms of central disorders of hypersomnolence. Results of this phase 1 study support the phase 2 clinical evaluation of oral alixorexton in patients with IH, NT2 and NT1.
Ronald R. Grunstein, Brendon J. Yee, Julia L. Chapman, Jian Eu Tai, Sheila Sivam, Craig Hopkinson, Daniel G. Smith, Alexandra Lovett, Shifang Liu, Sergey Yagoda, Bhaskar Rege   +10 more
wiley   +1 more source

Drug‐Induced Sialolithiasis—A Big‐Data Retrospective Study

Oral Diseases, EarlyView.
ABSTRACT Background Sialolithiasis pathophysiology is multifactorial, with systemic medications often hypothesised as a key contributor, particularly in older adults (Drug‐Induced Sialolithiasis). However, robust evidence supporting this theory is limited.
Gal Avishai, Gil Caspi, Akhilanand Chaurasia, Gavriel Chaushu, Daya Masri, Ehud Jonas   +5 more
wiley   +1 more source

Personal Values, Health Beliefs, and the Use of Complementary, Alternative and Integrative Medicine in Finland

Scandinavian Journal of Psychology, EarlyView.
ABSTRACT This study examines the relationships of personal values and health beliefs with past and intended use of complementary, alternative and integrative medicine (CAIM) in Finland. It also investigates the extent to which CAIM users and non‐users endorse holistic versus reductionistic health beliefs and whether experiencing benefits or harms from ...
Salla Ahola, Maija Pyykkönen, Pauliina Aarva   +2 more
wiley   +1 more source

Anticholinergic and sedative medications use among community dwelling older adults: risk for polypharmacy and poor physical function

BMC Geriatrics
Background Anticholinergic and/or sedative mediations are one of the most commonly prescribed medication groups in older adults. This study aimed to assess the prevalence of anticholinergic and/or sedative mediations use in community dwelling older ...
Aysu Selcuk, Volkan Atmis, Seher Sen, Emine Gemci, Busra Yurumez, Ahmet Yalcin, Asuman Bozkir, Sevgi Aras, Murat Varli   +8 more
doaj   +1 more source

Potential health benefits of cold‐water immersion: the central role of PGC‐1α

The Journal of Physiology, EarlyView.
Abstract figure legend Cold‐water immersion (CWI) elicits autonomic, somato‐motoric (shivering thermogenesis), endocrine and metabolic, sensory transduction, and local biophysical effects that may converge on the transcriptional co‐activator PGC‐1α (centre).
Erich Hohenauer, Wafa Douzi, Johannes Burtscher   +2 more
wiley   +1 more source