Results 131 to 140 of about 42,363 (276)

Population Pharmacokinetics of Ticagrelor during Veno‐Arterial ECMO in Acute Coronary Syndrome: Model‐Informed Dosing Simulations

open access: yesClinical Pharmacology &Therapeutics, Volume 120, Issue 1, Page 193-202, July 2026.
Although patients with acute coronary syndrome supported by veno‐arterial extracorporeal membrane oxygenation (VA‐ECMO) have a high risk of thrombosis and bleeding, antiplatelet pharmacology in this setting is not well defined. This prospective observational study investigated the population pharmacokinetics of ticagrelor and its active metabolite AR ...
Soyoung Kang   +9 more
wiley   +1 more source

An Explainable Machine Learning Model for Early Prediction of Incident Myocardial Injury in Patients With Severe Fever With Thrombocytopenia Syndrome

open access: yesJournal of Medical Virology, Volume 98, Issue 7, July 2026.
ABSTRACT This study aimed to develop an explainable machine learning–based model to enable early prediction of incident myocardial injury during hospitalization among patients with severe fever with thrombocytopenia syndrome (SFTS). This multicenter retrospective cohort study included and analyzed clinical data from 1,088 patients with SFTS who were ...
Xiang Li   +11 more
wiley   +1 more source

Systematic Review of Intravenous Ceftriaxone Administration in Animals

open access: yesVeterinary Medicine and Science, Volume 12, Issue 4, July 2026.
ABSTRACT Background Ceftriaxone is an antibiotic frequently prescribed in veterinary medical practice due to its effectiveness against several pathogenic microorganisms responsible for diseases in different animal species. Objective To select scientific articles from the academic databases PubMed and Web of Science that analysed the pharmacokinetic ...
Paula Maria Fernandes de Vasconcelos   +2 more
wiley   +1 more source

A Nationwide Assessment of Anticholestatic Therapy Uptake in Patients With Primary Biliary Cholangitis: Opportunities for Optimisation

open access: yesAlimentary Pharmacology &Therapeutics, Volume 64, Issue 2, Page 186-195, July 2026.
Among a nationwide population with primary biliary cholangitis, almost all people were prescribed ursodeoxycholic acid (UDCA). However, UDCA was insufficiently dosed in a one third of them. The results indicate that first‐line treatment can be optimized, particularly in those with a biochemical response and higher body weight.
Ellen Werner   +116 more
wiley   +1 more source

What's Your Diagnosis? A Case of Extreme Thrombocytosis in a Dog

open access: yes
Veterinary Clinical Pathology, EarlyView.
Stephanie F. Anderson   +5 more
wiley   +1 more source

Homozygous Loss‐of‐Function Variant in SLC20A1 Coding for Ubiquitous Phosphate Transporter PiT1 Is Associated With Multiple Developmental Abnormalities

open access: yesClinical Genetics, Volume 110, Issue 1, Page 64-72, July 2026.
Biallelic SLC20A1 loss‐of‐function variant causes a previously unrecognized multisystem developmental disorder. We report the first homozygous case presenting with tetralogy of Fallot, renal agenesis, polydactyly, and growth impairment. Transcriptome analysis of patient‐derived fibroblasts suggests significant dysregulation of pathways critical for ...
Eugénie Koumakis   +9 more
wiley   +1 more source

Extranodal natural killer/T‐cell lymphoma: From fatal to curable

open access: yesCA: A Cancer Journal for Clinicians, Volume 76, Issue 4, July/August 2026.
Abstract Extranodal natural killer (NK)/T‐cell lymphoma (ENKTCL) is one of the most aggressive non‐Hodgkin lymphomas characterized by NK‐cell or T‐cell origins, a geographic prevalence in Asian and South American populations, and Epstein–Barr virus (EBV) infection.
Jie Xiong   +12 more
wiley   +1 more source

Beyond Hemostasis: Platelet Biomarkers and Vascular‐Immune Crosstalk in Dengue

open access: yesThe FASEB Journal, Volume 40, Issue 12, 30 June 2026.
Several biomarkers are associated with platelet activation during dengue virus (DENV) infection. These include serum markers (AST, ALT, ferritin), platelet surface or secreted molecules (P‐selectin, PF4, RANTES, VEGF‐A, CD40L, TREM‐1, TLT‐1), immune and endothelial markers (TREM‐1, Ang‐1, Ang‐2), and viral components such as DENV EIII.
Amanda Beatriz Adriano da Silva‐Alencar   +6 more
wiley   +1 more source

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