Congenital hyperreninemic hypoaldosteronism: A case report [PDF]
SAGE Open Medical Case Reports, 2023 Congenital hypoaldosteronism is a rare autosomal recessive or dominant endocrinopathy with variable penetrance, secondary to primary defects in aldosterone synthesis that could lead to hypovolemia, hyponatremia, hyperkalemia, failure to thrive ...
Maria Elvira Yupanqui +7 more
doaj +3 more sources
Pseudo‐Hypoaldosteronism Type 2 due to New Variants of KLHL3 Gene Diagnosed in an Adult Woman With Very High Sensitivity to Hydrochlorothiazide [PDF]
Clinical Case ReportsWe report a case of pseudo‐hypoaldosteronism type 2 (PHA II) in a hypertensive 55‐year‐old woman who carried new variants of the KLHL3 gene. Hypersensitivity to hydrochlorothiazide was noted.
Massimo Giusti +2 more
doaj +4 more sources
Genetic Insights and Lifelong Management of Aldosterone Synthase Deficiency: A Case of Hyperreninemic Hypoaldosteronism [PDF]
Clinical Case ReportsAldosterone synthase deficiency is a rare cause of neonatal salt‐wasting and failure to thrive. Routine newborn electrolyte screening after 5 days of life is vital for early detection and prevention of life‐threatening crises.
Mian Muhammad Hassan Ahmed +4 more
doaj +4 more sources
Trends in Pediatrics, 2021 Primary hypoaldosteronism is a rare autosomal recessive disorder that causes defects in aldosterone synthase enzyme activity due to an inactivating mutation in the CYP11B2 gene.
Merve Sakar +6 more
doaj +3 more sources
Clinical manifestations and associated factors in acquired hypoaldosteronism in endocrinological practice [PDF]
Frontiers in Endocrinology, 2022 IntroductionHypoaldosteronism can be congenital or acquired, isolated or part of primary adrenal insufficiency, and caused by an aldosterone deficit, resistance, or a combination of both. Reduced mineralocorticoid action can induce a decrease in urine K+
Jorge Gabriel Ruiz-Sánchez +11 more
doaj +2 more sources
Primary acquired hypoaldosteronism
Kidney International, 1985 Case presentation A 57-year-old female, a retired beautician, was referred to Parkiand Memorial Hospital for evaluation and treatment of persistent hyperkalemia. She had been in excellent health until approximately 12 years earlier, when she underwent a laminectomy for a herniated nucleus pulposus.
Juha P. Kokko
openaire +3 more sources
Isolated hypoaldosteronism managed by DOCP in a dog with chronic kidney disease and hypercortisolism
Veterinary Medicine and Science, 2022 A 13‐year‐old spayed female Schnauzer dog with chronic kidney disease (CKD; International Renal Interest Society stage 2, non‐proteinuric, normotensive), diabetes mellitus, hypercortisolism and myxomatous mitral valve degeneration (American College of ...
Su‐Min Park +5 more
doaj +2 more sources
Heparin-Induced Hyperkalemia Assessment Utilizing the Naranjo Adverse Drug Reaction Probability Scale: A 40-Year Systematic Review [PDF]
PharmacyBackground: Adverse drug reactions have been reported as leading causes of morbidity and mortality. Unfractionated heparin- and low-molecular-weight heparin-induced hyperkalemia are side effects that have been reported in approximately 7 to 8% of heparin-
Divita Singh +2 more
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Isolated hypoaldosteronism is a cause of hypovolemic but not euvolemic hyponatremia [PDF]
Endocrine ConnectionsIntroduction: Hypoaldosteronism is characterized by hyperkalemia, and/or hypovolemic hyponatremia (HH), often accompanied by metabolic acidosis. HH is typical of hypoaldosteronism, whereas euvolemic hyponatremia (EH) is not.
Jorge Gabriel Ruiz-Sánchez +5 more
doaj +2 more sources
Case Report: UMOD gene mutation and phenotypic overlap with REN in autosomal dominant tubulointerstitial kidney disease [PDF]
Frontiers in GeneticsAutosomal dominant tubulointerstitial kidney disease (ADTKD) is a rare monogenic kidney disorder characterized by progressive tubular atrophy and interstitial fibrosis. It is primarily associated with pathogenic variants in genes such as UMOD (uromodulin)
Jingying Xu +9 more
doaj +2 more sources