Results 61 to 70 of about 3,080 (230)

Persistent severe hyperkalemia following surgical treatment of aldosterone-producing adenoma

Journal of Research in Medical Sciences, 2020
Primary aldosteronism is one of the most common causes of secondary hypertension. This condition is characterized by autonomous hypersecretion of aldosterone which produces sodium retention and potassium excretion, resulting in high blood pressure and ...
Cristina Preda, Laura Claudia Teodoriu, Sarolta Placinta, Alexandru Grigorovici, Stefana Bilha, Christina M Ungureanu   +5 more
doaj   +1 more source

Nephrogenic Syndrome of Inappropriate Antidiuresis Mimicking Hyporeninemic Hypoaldosteronism: Case Report of Two Infants

JCRPE, 2023
Nephrogenic syndrome of inappropriate antidiuresis (NSIAD) is an X-linked disease caused by activating mutations in the arginine vasopressin (AVP) receptor-2 (AVPR2) gene.
Jamala Mammadova, Cengiz Kara, Eda Çelebi Bitkin, Elif İzci Güllü, Murat Aydın   +4 more
doaj   +1 more source

mTORC2 critically regulates renal potassium handling [PDF]

, 2016
The mTOR pathway orchestrates cellular homeostasis. The rapamycin-sensitive mTOR complex (mTORC1) in the kidney has been widely studied; however, mTORC2 function in renal tubules is poorly characterized.
Ahmed, Azaz, Arnold, Frederic, Artunc, Ferruh, Bertog, Marko, Cordts, Tomke, Grahammer, Florian, Hall, Michael N., Huber, Tobias B., Korbmacher, Christoph, Negrea, Silvio, Nesterov, Viatcheslav, Ruegg, Marcus A., Sandner, Lukas, Steinhardt, Frederic, Walz, Gerd   +14 more
core   +1 more source

Normal Immune Function in a Newborn With Early Identification of a SAMD9 Mutation Presenting With Growth Restriction, Thrombocytopenia, and Primary Adrenal Insufficiency

Clinical Case Reports, Volume 13, Issue 11, November 2025.
A de novo SAMD9 variant G1048R is associated with MIRAGE syndrome symptoms in a neonate. SAMD9 G1048R's predicted tertiary structure has similarity to known MIRAGE variants. SAMD9 expression is increased in pediatric viral infection. Neonatal MIRAGE may lack immune deficiency and myelodysplastic syndrome.
Kevin MingJie Gao, Qiu Yu Judy Huang, Polly Huang, Anum Muzaffar, Ramin Beheshti, Robert Wood, Jennifer Dantzer, Maria J. Gutierrez   +7 more
wiley   +1 more source

Successful matched unrelated donor hematopoietic stem cell transplantation for infantile Wolman disease

Pediatric Hematology Oncology Journal, 2023
Introduction: Wolman disease is a rare genetic disorder with an autosomal recessive inheritance. A mutation in the LIPA gene causes lysosomal acid lipase (LAL) deficiency results in lipid storage and adrenal insufficiency.
Indira Jayakumar, Anupama Gude, Murarji Renangi, Soundaram Valliyappan, Venkateswaran Vellaichamy Swaminathan, Satishkumar Meena, Harika Varla, Rumesh Chandar, Ramya Uppuluri, Revathi Raj   +9 more
doaj   +1 more source

Disruption of the with no lysine kinase-STE20-proline alanine-rich kinase pathway reduces the hypertension induced by angiotensin II [PDF]

, 2018
Objective: The hypertensive effect of angiotensin II (AngII), a peptide hormone, is dependent on its intrarenal actions and the activation of the renal Na–Cl cotransporter (NCC), by AngII requires integrity of the with no lysine kinase/STE20-proline ...
Alessi, Dario, Bobadilla, Norma A., Castaneda-Bueno, Maria, Gamba, Gerardo, Graciela Cervantes-Perez, Luz, Jimenez, Jose V., Rojas-Vega, Lorena, Vazquez, Norma   +7 more
core   +3 more sources

Retrospective Evaluation of the Prognosis and Prevalence of Hyperchloremia in Dogs and Cats

Journal of Veterinary Emergency and Critical Care, Volume 35, Issue 6, Page 710-722, November/December 2025.
ABSTRACT Objective To determine the prevalence, case‐fatality rate, and primary disease processes associated with high corrected chloride concentration (hyper[Cl−]) in dogs and cats. Design Single‐center retrospective study. Setting Electrical medical records were reviewed to identify dogs and cats with at least one chloride and sodium concentration ...
Yu Ueda, Steven E. Epstein, Kate Hopper
wiley   +1 more source

Gain of function mutants: Ion channels and G protein-coupled receptors [PDF]

, 2000
Many ion channels and receptors display striking phenotypes for gain-of-function mutations but milder phenotypes for null mutations. Gain of molecular function can have several mechanistic bases: selectivity changes, gating changes including constitutive
Karschin, Andreas, Lester, Henry A.
core   +1 more source

Hyperkalemia in Clinical Practice, an Important Reminder of Testing Modality

Clinical Case Reports, Volume 13, Issue 10, October 2025.
ABSTRACT We describe a patient with hyperkalemia and ECG changes with persistent mild hyperkalemia without ECG changes following treatment. Their hyperkalemia was confounded by the presence of true hyperkalemia due to an acute kidney injury and pseudohyperkalemia due to significant thrombocytosis.
Andrew G. Turner, Deepak L. Vardesh
wiley   +1 more source

Diabetes mellitus and hyperkalemic renal tubular acidosis: case reports and literature review

Brazilian Journal of Nephrology
Hyporeninemic hypoaldosteronism, despite being common, remains an underdiagnosed entity that is more prevalent in patients with diabetes mellitus.
Carlos Henrique Pires Ratto Tavares Bello, João Sequeira Duarte, Carlos Vasconcelos   +2 more
doaj   +1 more source