Results 121 to 130 of about 24,784 (271)

Sympathetic stimulation can compensate for hypocalcaemia‐induced bradycardia in human and rabbit sinoatrial node cells

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend AC: adenylyl cyclase, APT: adenosine triphosphate, AMP: adenosine monophosphate, cAMP: cyclic adenosine monophosphate, PDE: phosphodiesterase, PKA: protein kinase A, PPT: protein phosphatase, P: phosphorylation, RyR: ryanodine receptor, SERCA: sarcoplasmic/endoplasmic reticulum Ca2+‐adenosine triphosphatase, SR: sarcoplasmic ...
Moritz Linder   +4 more
wiley   +1 more source

Feasibility of Atezolizumab in Combination With Chemotherapy for Children With Relapsed or Refractory Solid Tumors

open access: yesPediatric Blood &Cancer, Volume 72, Issue 12, December 2025.
ABSTRACT Background Combining immune checkpoint inhibitors (ICI) with chemotherapy may improve treatment response in children with solid tumors. We sought to determine the feasibility of combining vincristine, irinotecan, and temozolomide with the ICI atezolizumab in children with relapsed or refractory solid tumors (VITAS;). Methods Patients ≥6 months
Matthew E. Campbell   +16 more
wiley   +1 more source

Outcomes of surgical treatment of thyroid disease in children

open access: yesБюллетень сибирской медицины, 2017
Background. In recent years there has been a tendency of increase in the proportion of nodular goiter and Graves’ disease in thyroid pathology in children, which necessitates a choice of rational tactics for treatment of these diseases.
Olga S. Rogova   +8 more
doaj   +1 more source

Serum calcium and magnesium abnormalities in patients with status epilepticus: a single centre tertiary care experience [PDF]

open access: yes, 2015
Electrolyte imbalances frequently cause seizures, and these seizures may be the sole presenting symptom. Seizures are especially common in patients with sodium disorders, hypocalcemia, and hypomagnesemia.
Badshah, Mazhar   +4 more
core   +1 more source

PIK3C2A‐Related Clinical Phenotype and Cellular Charaterization Linked to Functional SHH Primary Cilia Defect

open access: yesClinical Genetics, Volume 108, Issue 6, Page 696-707, December 2025.
Trio exome sequencing allowed the identification of two novel compound heterozygous variants in PIK3C2A, defining the fifth family presenting a PIK3C2A‐related syndrome characterized by pulverulent cataracts and deafness. Functional testing revealed impaired PI metabolism and primary dysfunction phenotype.
Adella Karam   +9 more
wiley   +1 more source

Identification of risk factors and development of detection algorithm for denosumab‐induced hypocalcaemia

open access: yesJournal of Clinical Pharmacy and Therapeutics, 2018
This study used electronic medical records to identify risk factors and establish a detection algorithm for denosumab‐induced hypocalcaemia.
T. Imatoh   +9 more
semanticscholar   +1 more source

Advanced Image‐Guidance and Surgical‐Navigation Techniques for Real‐Time Visualized Surgery

open access: yesAdvanced Science, Volume 12, Issue 41, November 6, 2025.
This review comprehensively summarizes advances in surgical navigation, covering both established and emerging intraoperative imaging technologies. It highlights mechanisms, advantages, limitations, and clinical applications, while emphasizing interdisciplinary collaboration.
Xiaoxiao Fan   +9 more
wiley   +1 more source

The Autoimmune March: Bullous Lichen Planus and New‐Onset Lupus Erythematosus Occurring After COVID‐19 mRNA Vaccination in a Filipino Female With Rheumatoid Arthritis

open access: yesClinical Case Reports, Volume 13, Issue 11, November 2025.
Images of the patient’s skin biopsy over time from 2019 (A), 2021 (B) and 2023 (C). ABSTRACT The novelty of coronavirus disease 2019 (COVID‐19) vaccines implies the possibility of unexpected reactions. There is also a relative paucity of data regarding interactions between COVID‐19 immunization and preexisting autoimmune disease.
Patrick Antonne Gonzalez   +3 more
wiley   +1 more source

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