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Immunoglobulin cleavage by hypochlorous acid treatment

Clinica Chimica Acta, 1995
IgA, IgG and IgM were cleaved by hypochlorous acid treatment. The apparent calculated molecular masses of three polypeptides obtained from IgA were 81.1. 25.8 and 13.9 kDa. The amounts of released IgA fragments were proportional to the amount of HOCl employed.
R, Drozdz, I, Guevara, J W, Naskalski
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Reactions of pholasin with peroxidases and hypochlorous acid

Free Radical Biology and Medicine, 2000
The ability of myeloperoxidase (MPO) and horseradish peroxidase (HRP) to induce chemiluminescence (CL) in Pholasin (Knight Scientific, Plymouth, UK), the photoprotein of the Common Piddock Pholas dactylus, was studied. The oxidation of Pholasin by compound I or II of HRP induced an intense light emission, whereas native HRP showed only a small effect ...
S, Reichl   +4 more
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Effects of hypochlorous acid on unsaturated phosphatidylcholines

Free Radical Biology and Medicine, 2001
Effects of hypochlorous acid and of the myeloperoxidase-hydrogen peroxide-chloride system on mono- and polyunsaturated phosphatidylcholines were analyzed by means of matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS).
J, Arnhold   +4 more
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Hypochlorous acid scavenging capacity of garlic

Phytotherapy Research, 2007
AbstractThe ability of the following aqueous garlic extracts to scavenge hypochlorous acid (HOCl) was studied: (a) unheated extract of raw garlic (RG), (b) heated extract of raw garlic (HRG), (c) extract of boiled garlic cloves (BG) and (d) extract of microwave‐treated garlic cloves (MG).
José, Pedraza-Chaverrí   +2 more
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THE DECOMPOSITION OF HYPOCHLOROUS ACID

Canadian Journal of Chemistry, 1952
The rate of decomposition of hypochlorous acid has been measured in aqueous solution in the presence of much sodium hypochlorite. The rate is nearly independent of the hypochlorite concentration, and proportional to the square of the hypochlorous acid concentration. Hence the mechanism proposed is[Formula: see text][Formula: see text]The first step is
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Kinetics and Mechanisms of Hypochlorous Acid Reactions

Archives of Biochemistry and Biophysics, 1995
Hypochlorous acid (HOCl) is a strong oxidant formed in neutrophils by the myeloperoxidase-catalyzed oxidation of chloride. Using stopped-flow with spectrophotometric detection, HOCl was found to react very rapidly with glutathione and ascorbate and less rapidly with taurine.
L K, Folkes, L P, Candeias, P, Wardman
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Chlorination of Betacyanins in Several Hypochlorous Acid Systems

Journal of Agricultural and Food Chemistry, 2016
This study presents a comparative evaluation of chlorination of betanin, betanidin, and neobetanin exposed to sodium hypochlorite and myeloperoxidase (MPO)/H2O2/Cl(-) systems. For betanin/betanidin, the chlorination takes place at the aglycone unit, but for neobetanin, no chlorinated products in the reaction mixtures can be detected.
Sławomir Wybraniec   +2 more
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The Reaction of Hemoproteins with Hypochlorous Acid

Chemistry Letters, 2008
Abstract We have studied absorption spectral changes and heme modifications in the reaction of horseradish peroxidase (HRP), myoglobin (Mb), or bovine liver catalase (BLC) with hypochlorous acid (HOCl). Under acidic condition, HOCl is easily released from an FeIII–HOCl complex.
Shin-ichi Ozaki   +3 more
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Hypochlorous Acid Chemistry in Mammalian Cells—Influence on Infection and Role in Various Pathologies

International Journal of Molecular Sciences, 2022
Francisco J Plou   +2 more
exaly  

Hypochlorous acid

Reactions Weekly, 2016
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