Results 191 to 200 of about 26,374 (235)
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Hypochlorous Acid Is a Potent Inhibitor of Acetylcholinesterase
Toxicology and Applied Pharmacology, 2002The role of hydrogen peroxide and peroxynitrite in the induction of airway hyperreactivity has been well described. Another reactive species which is formed during airway inflammation is hypochlorous acid (HOCl). In the present investigation the effect of HOCl on cholinergic innervation of the airway was investigated.
den Hartog, G.J.M. +4 more
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Wound cleansing: benefits of hypochlorous acid
Journal of Wound Care, 2020Cleansing provides an opportunity to remove pathogens from the wound bed, thereby preventing an increase in the bioburden and delayed healing.
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Chlorogenic Acid as a Natural Scavenger for Hypochlorous Acid
Biochemical and Biophysical Research Communications, 1995The effect of chlorogenic acid (CGA) on the killing of Escherichia coli by hypochlorous acid (HOCI) was examined. CGA prevented E. coli from bactericidal action of HOCI in a concentration-dependent manner. HOCI reacted rapidly with CGA. By comparison with the one- and two-electron oxidation products produced by peroxidase and phenolase reactions ...
Y, Kono +4 more
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Immunoglobulin cleavage by hypochlorous acid treatment
Clinica Chimica Acta, 1995IgA, IgG and IgM were cleaved by hypochlorous acid treatment. The apparent calculated molecular masses of three polypeptides obtained from IgA were 81.1. 25.8 and 13.9 kDa. The amounts of released IgA fragments were proportional to the amount of HOCl employed.
R, Drozdz, I, Guevara, J W, Naskalski
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Reactions of pholasin with peroxidases and hypochlorous acid
Free Radical Biology and Medicine, 2000The ability of myeloperoxidase (MPO) and horseradish peroxidase (HRP) to induce chemiluminescence (CL) in Pholasin (Knight Scientific, Plymouth, UK), the photoprotein of the Common Piddock Pholas dactylus, was studied. The oxidation of Pholasin by compound I or II of HRP induced an intense light emission, whereas native HRP showed only a small effect ...
S, Reichl +4 more
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Reaction of γ‐Tocopherol with Hypochlorous Acid
Lipids, 2007AbstractIn addition to being a very good antioxidant, γ‐tocopherol is also an excellent electrophile trap. This is a study of the reactivity of γ‐tocopherol with hypochlorous acid/hypochlorite, a potential biological foe that is both an oxidant and an electrophile. Aqueous sodium hypochlorite (1.72 mmol; pH 7.4) was stirred with γ‐tocopherol (0.12 mmol)
Quyen, Nguyen, Peter T, Southwell-Keely
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Effects of hypochlorous acid on unsaturated phosphatidylcholines
Free Radical Biology and Medicine, 2001Effects of hypochlorous acid and of the myeloperoxidase-hydrogen peroxide-chloride system on mono- and polyunsaturated phosphatidylcholines were analyzed by means of matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS).
J, Arnhold +4 more
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THE DECOMPOSITION OF HYPOCHLOROUS ACID
Canadian Journal of Chemistry, 1952The rate of decomposition of hypochlorous acid has been measured in aqueous solution in the presence of much sodium hypochlorite. The rate is nearly independent of the hypochlorite concentration, and proportional to the square of the hypochlorous acid concentration. Hence the mechanism proposed is[Formula: see text][Formula: see text]The first step is
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Hypochlorous acid mobilizes cellular zinc
Canadian Journal of Physiology and Pharmacology, 1991Neutrophil oxidants, in particular hypochlorous acid (HOCl), can cause injury to healthy tissues at sites of inflammation. Some of this injury may be caused by oxidant-induced mobilization of metals. We examined the ability of HOCl to mobilize Zn2+ in target tissues.
H, Fliss, M, Ménard, M, Desai
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Hypochlorous acid scavenging capacity of garlic
Phytotherapy Research, 2007AbstractThe ability of the following aqueous garlic extracts to scavenge hypochlorous acid (HOCl) was studied: (a) unheated extract of raw garlic (RG), (b) heated extract of raw garlic (HRG), (c) extract of boiled garlic cloves (BG) and (d) extract of microwave‐treated garlic cloves (MG).
José, Pedraza-Chaverrí +2 more
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