Results 161 to 170 of about 113,928,997 (189)
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Effect of Structural Modification on Photodynamic Activity of Hypocrellins
Photochemistry and Photobiology, 2001Aluminum ion complexed 5,8-di-Br-hypocrellin B is a new water-soluble perylenequinonoid derivative with enhanced absorption over hypocrellin B (HB) in the phototherapeutic window (600-900 nm). Electron paramagnetic resonance and 9,10-diphenyl-anthracene bleaching methods were used to investigate the photosensitizing activity of [AL2(5,8-di-Br-HB)Cl4]n ...
J, Ma, J, Zhao, L, Jiang
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Spectroscopic studies on the interaction of Ga3+-hypocrellin A with myoglobin
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2014In this article, the interaction mechanism of Ga(3+)-hypocrellin A (Ga(3+)-HA) with myoglobin (Mb) is studied in detail through various spectroscopic technologies. UV-vis absorption and fluorescence spectra demonstrate the interaction process. The Stern-Volmer plot and the time-resolved fluorescence study suggest the fluorescence quenching mechanism of
Wenli, Xie +6 more
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Antibacterial activity of hypocrellin A against Staphylococcus aureus
World Journal of Microbiology and Biotechnology, 2012The antibacterial activity and acting mechanism of hypocrellin A (HA) were conducted regarding in vitro activity of HA on Staphylococcus aureus GZ86 by analyzing the growth, permeability, and morphology of the bacterial cells following treatment with HA. The experimental results indicated 1.5 mg/l HA could completely inhibit the growth of 10⁷ CFU/ml S.
Wen, Du +4 more
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Prediction on amphiphilicity of hypocrellin derivatives
Science in China Series B, 2002Hypocrellins are most suitable for photodynamic therapy (PDT) of the diseases occurring in the superficial layer, such as microvascular diseases, because of their special absorption spectral properties. However, hypocrellins and most of their derivatives are basically lipophilic, while the hydrophilic derivatives lose the PDT activity in vivo ...
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The Role of Oxygen in the Antiviral Activity of Hypericin and Hypocrellin
Photochemistry and Photobiology, 1998AbstractThe light‐induced antiviral activity of hypericin and hypocrellin in the presence and absence of oxygen was examined under experimental conditions where the effect of oxygen depletion could be quantified. There was a significant reduction of light‐induced antiviral activity of hypericin and hypocrellin under hypoxic conditions.
J, Park +4 more
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Photo-induced interactions of hypocrellin A with phycobiliproteins
Research on Chemical Intermediates, 2004Photo-induced interaction of hypocrellin A (HA) with a water-soluble protein (C-phycocyanin, C-PC) was studied by monitoring the changes of the photo-physical properties of C-PC, as well as those of HA. It was found that the solubility of HA in phosphate-buffered saline solution was greatly promoted in the presence of C-PC. Furthermore, energy transfer
Baozhong Zhao, Jie Xie, Jingquan Zhao
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Photochemical properties of hypocrellin A, B and their oxides
Chinese Journal of Chemistry, 1990AbstractHypocrellin A and B in methanol were autosensitized and photooxygenated to 1, 4, 6, 7 and 2, 5, 8, 9 respectively. 1 in methanol was photooxygenated to 6 and 7 under the sensitization by HB. 1 in methanol was photooxygenated to 7 under the sensitization by Rose bengal.
Kai‐Hong Zhao, Li‐Jin Jiang
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A theoretical study on photobleaching mechanisms of hypocrellins
Dyes and Pigments, 2005Abstract In this paper, quantum chemical method RHF/6-31G(d,p)//AM1 was employed to investigate the photobleaching behaviors of hypocrellins. It is found that frontier charge rather than Mulliken charge is an applicable parameter to predict the 1 O 2 - and O 2 − -addition positions of the pigments; accordingly some experimental observations on the
L WANG, X WANG, H ZHANG
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Synthesis and ESR investigation of hypocrellin glycoside
Tetrahedron Letters, 1998Abstract A glycoside derived from hypocrellin B was designed and synthesized using an improved Konigs-Knorr reaction. The water-solubility and red absorption of the resulting product was enhanced significantly over hypocrellin B. Electron spin resonance (ESR) measurements indicated that this glycoside remained photodynamically active in terms of Type
Yu-Ying He, Jing-Yi An, Li-Jin Jiang
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