Comparative proteomics analysis of Shiraia bambusicola revealed a variety of regulatory systems on conidiospore formation [PDF]
Frontiers in MicrobiologyShiraia bambusicola is a typical parasitic medicinal fungus of the family Shiraiaceae. The fruiting bodies of S. bambusicola cannot be cultivated artificially, and active substances can be effectively produced via fermentation.
Wen Du +14 more
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Volatiles of Shiraia fruiting body-associated Pseudomonas putida No.24 stimulate fungal hypocrellin production [PDF]
Synthetic and Systems Biotechnology, 2023 Hypocrellins are major bioactive perylenequinones from Shiraia fruiting bodies and have been developed as efficient photosensitizers for photodynamic therapy.
Rui Xu +5 more
doaj +2 more sources
Effects of branched-chain amino acids on Shiraia perylenequinone production in mycelium cultures [PDF]
Microbial Cell Factories, 2023 Background Perylenequinones from Shiraia fruiting bodies are excellent photosensitizers and widely used for anti-cancer photodynamic therapy (PDT). The lower yield of Shiraia perylenequinones becomes a significant bottleneck for their medical application.
Wen Hao Shen +5 more
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Contrasting regulation of live Bacillus cereus No.1 and its volatiles on Shiraia perylenequinone production [PDF]
Microbial Cell Factories, 2022 Background Fungal perylenequinones (PQs) are a class of photoactivated polyketide mycotoxins produced by plant-associated fungi. Hypocrellins, the effective anticancer photodynamic therapy (PDT) agents are main bioactive PQs isolated from a bambusicolous
Rui Xu +5 more
doaj +2 more sources
Production of fungal hypocrellin photosensitizers: Exploiting bambusicolous fungi and elicitation strategies in mycelium cultures [PDF]
MycologyHypocrellins, a group of naturally occurring perylenequinone pigments produced by Shiraia bambusicola, are notable for their potential use in photodynamic therapy (PDT) for treating cancers and viruses.
Xin Ping Li +3 more
doaj +2 more sources
Melatonin-Induced Inhibition of Shiraia Hypocrellin A Biosynthesis Is Mediated by Hydrogen Peroxide and Nitric Oxide [PDF]
Journal of Fungi, 2022 Melatonin (MLT), an evolutionarily conserved pleiotropic molecule, is implicated in numerous physiological processes in plants and animals. However, the effects of MLT on microbes have seldom been reported.
Wenjuan Wang +5 more
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Phylogenetic Position of Shiraia-Like Endophytes on Bamboos and the Diverse Biosynthesis of Hypocrellin and Hypocrellin Derivatives [PDF]
Journal of Fungi, 2021 The main active ingredients of the fruiting bodies of Shiraia bambusicola and Rubroshiraia bambusae are Hypocrellins, belonging perylenequinones with potential photodynamic activity against cancer and microbial diseases.
Xin Tong +4 more
doaj +2 more sources
Interplay between Shiraia and its fruiting body-associated Rhodococcus sp. No. 3 via hypocrellin A and carotenoid biosynthesis [PDF]
MycologyHypocrellin A (HA), a bioactive perylenequinone from Shiraia fruiting bodies, serves as an efficient photodynamic therapy photosensitiser. While these fruiting bodies harbour diverse bacteria, host-microbe functional interactions remain poorly ...
Li Ping Zheng +4 more
doaj +2 more sources
Glucose-6-Phosphate Dehydrogenase Modulates Shiraia Hypocrellin A Biosynthesis Through ROS/NO Signaling in Response to Bamboo Polysaccharide Elicitation [PDF]
MoleculesHypocrellin A (HA), a photodynamic perylenequinone pigment from Shiraia fruiting bodies, functions as an efficient photosensitizer for clinical photodynamic therapy.
Xinping Li +4 more
doaj +2 more sources
Spermidine stimulates hypocrellin A biosynthesis through nitric oxide signaling in Shiraia sp. S9 [PDF]
Bioresources and BioprocessingHypocrellin A (HA), a photoactive perylenequinone from the bambusicolous Shiraia fungi, possesses potent photodynamic anticancer and antimicrobial properties. However, the signaling mechanisms governing its biosynthesis remain poorly understood.
Li Ping Zheng +4 more
doaj +2 more sources