Results 61 to 70 of about 113,928,997 (189)

Roadmap to Nanomedical Applications: Nanotoxicology and In Vitro Guidelines for Lanthanide‐Doped Luminescence Nanothermometers

Advanced NanoBiomed Research, Volume 5, Issue 6, June 2025.
Lanthanide‐based luminescence nanothermometry holds multifaceted potential for nanomedical applications, yet despite significant research advances, clinical translation of the engineered nanomaterials is still controversial and widely disputed. This is related to crucial nanotoxicological aspects that must be addressed at the preclinical level ...
Simona Premcheska, Andre G. Skirtach, Anna M. Kaczmarek   +2 more
wiley   +1 more source

Solvent Dependence on the Intramolecular Excited-State Proton or Hydrogen Atom Transfer in Hypocrellin [PDF]

, 1997
Hypocrellin and its analog, hypericin (Figure 1), are naturally occurring quinones that have been used for centuries as folk medicines in the orient and the occident and that have attracted much interest because of their light-induced toxicity toward the
Petrich, Jacob, English, D., Das, K.
core  

Excited-State Processes in Polycyclic Quinones:  The Light-Induced Antiviral Agent, Hypocrellin, and a Comparison with Hypericin [PDF]

, 1996
Hypocrellin is a naturally occurring perylene quinone that possesses light-induced antiviral activity, most notably against the human immunodeficiency virus (HIV), as does the related molecule, hypericin.
Petrich, Jacob, English, D., Fehr, Michael, Das, K., Smirnov, Alexandre   +4 more
core  

The Combination of Active‐Targeted Photodynamic Therapy and Photoactivated Chemotherapy for Enhanced Cancer Treatment

Journal of Biophotonics, Volume 18, Issue 6, June 2025.
Photoactivated chemotherapy (PACT), an oxygen‐independent light‐based therapy, utilizes chemotherapeutic regimens that remain inert until exposed to light, allowing target‐specific activation while minimizing off‐target toxicity. The integration of these techniques has the potential to improve selectivity and yield synergistic cytotoxic effects that ...
Nkune Williams Nkune, Heidi Abrahamse
wiley   +1 more source

Inducing perylenequinone production from a bambusicolous fungus Shiraia sp. S9 through co-culture with a fruiting body-associated bacterium Pseudomonas fulva SB1

Microbial Cell Factories, 2019
Background Fungal perylenequinonoid (PQ) pigments from Shiraia fruiting body have been well known as excellent photosensitizers for medical and agricultural uses. The fruiting bodies are colonized by a diverse bacterial community of unknown function.
Yan Jun Ma, Li Ping Zheng, Jian Wen Wang
doaj   +1 more source

Electrospun Nanofiber Platforms for Photodynamic Therapy: Role and Efficacy in Cancer, Antimicrobial, and Wound Healing Applications

Macromolecular Materials and Engineering, Volume 310, Issue 5, May 2025.
Electrospun nanofibers provide a unique platform for photosensitizers, due to their large surface area and biocompatibility, improving both loading efficiency and controlled release. The photosensitizer‐modified nanofibers are activated upon light exposure, and produce reactive oxygen species to treat cancer, pathogen infections, and wounds.
Aslı Eldem, Yamaç Tekintaş, Muhammed Ucuncu, Nesrin Horzum   +3 more
wiley   +1 more source

Hypocrellin productions (A), biomasses (B) and amylase activities (C) when five strains were cultured under SSF.

, 2018
Hypocrellin productions (A), biomasses (B) and amylase activities (C) when five strains were cultured under SSF.
Ye Zhao (39959), Huaxiang Deng (5167982), Zhengbing Guan (3095238), Xiaohui Zheng (305099), Zhecun Xu (5171552), Xiangru Liao (2047639), Yujie Cai (431517), Ruijie Gao (5167979)   +7 more
core   +1 more source

Bacteria Associated With Shiraia Fruiting Bodies Influence Fungal Production of Hypocrellin A

Frontiers in Microbiology, 2019
Hypocrellin A (HA) is a natural red perylenequinone pigment from Shiraia fruiting body, which was used clinically on various skin diseases and developed as a photodynamic therapy agent against cancers.
Yan Jun Ma, Li Ping Zheng, Jian Wen Wang
doaj   +1 more source

Design of Aromatic Interaction Networks in a Protein Cage Modulated by Fluorescent Ligand Binding

Advanced Science, Volume 12, Issue 15, April 17, 2025.
The study presents a novel system designed to control protein dynamics by orientational changes of aromatic residues triggered by ligand binding. By creating aromatic pockets within protein cages and binding fluorescent molecules via π–π interactions, the study achieves cooperative conformational change verified through X‐ray crystallography.
Yuki Hishikawa, Taiga Suzuki, Basudev Maity, Hiroki Noya, Michito Yoshizawa, Asuka Asanuma, Yuri Katagiri, Satoshi Abe, Satoru Nagatoishi, Kouhei Tsumoto, Takafumi Ueno   +10 more
wiley   +1 more source

Cell death: The underlying mechanisms of photodynamic therapy for skin diseases

Interdisciplinary Medicine, Volume 3, Issue 2, March 2025.
Photodynamic therapy has significant potential in the treatment of skin diseases though it has some limitations. A thorough understanding of the underlying mechanism is integral to solving these problems. This review focuses on the induction of cell death and its relevant pathways.
Haoxin Li, Jingjie Shen, Chunfu Zheng, Ping Zhu, Hong Yang, Yixiao Huang, Xinru Mao, Zhilu Yang, Guodong Hu, Yinghua Chen   +9 more
wiley   +1 more source