Results 51 to 60 of about 113,928,997 (189)
Microbial Cell Factories, 2022 Background Fungal perylenequinones (PQs) are a class of photoactivated polyketide mycotoxins produced by plant-associated fungi. Hypocrellins, the effective anticancer photodynamic therapy (PDT) agents are main bioactive PQs isolated from a bambusicolous
Rui Xu +5 more
doaj +1 more source
Approaches to Enhance Photodynamic Therapy of Lung Cancer: Potential Application of Nanoparticles
Advanced NanoBiomed Research, Volume 5, Issue 12, December 2025.Bioactive ligand‐targeted nanocarriers can accommodate functionalization with numerous targeting ligands for effective delivery of photosensitizers (PSs) within targeted photodynamic therapy. Various targeting moieties including peptides, antibodies, carbohydrates, aptamers, proteins, and PS anticancer molecules can be attached to nanomaterials.
Nokuphila Winifred Nompumelelo Simelane +1 more
wiley +1 more source
Perylenequinone Natural Products: Total Synthesis of Hypocrellin A [PDF]
The Journal of Organic Chemistry, 2009 An efficient and stereoselective total synthesis of the perylenequinone natural product hypocrellin A (1) is described. The key features include a potentially biomimetic 1,8-diketone aldol cyclization to set the centrochiral C7,C7'-stereochemistry, bis(trifluoroacetoxy)iodobenzene mediated oxygenation, a palladium-catalyzed decarboxylation, and an ...
Erin M, O'Brien +4 more
openaire +2 more sources
Roles of Oxygen and Photoinduced Acidification in the Light-Dependent Antiviral Activity of Hypocrellin A [PDF]
, 1995 Hypocrellin A displays photoinduced antiviral activity, in particular against the human immunodeficiency virus (HIV), as does its counterpart, hypericin. Although hypocrellin A, like hypericin, executes an excited-state intramolecular proton transfer, it
Carpenter, S. +3 more
core
Green‐Synthesised Nanoconjugates: Advancing Targeted Photodynamic Therapy for Lung Cancer
Chemistry &Biodiversity, Volume 22, Issue 12, December 2025.ABSTRACT Lung cancer is a type of cancer that develops around the airways or lungs and continues to be the leading cause of cancer‐related deaths worldwide. This has necessitated the need for innovative therapeutic strategies to overcome the limits of existing therapies such as surgery, chemotherapy and radiotherapy.
Njabulo Henry Sibanda +2 more
wiley +1 more source
, 2007 Increased endothelin-1 (ET-1), vascular endothelial growth factor (VEGF) and activation of protein kinase C (PKC) are co-contributors to endothelial hyperpermeability in diabetes.
Seale, PJ, Dang, L, Qu, X
core +1 more source
Emerging applications of rare‐earth fluoride nanocrystals in medicine and biotechnologies
Responsive Materials, Volume 3, Issue 4, November 2025.Rare‐earth fluoride nanocrystals (REFNCs) exhibit high responsivity and can be used as multi‐modal agents in medicine and theranostics. This review summarizes recent advances in REFNCs, covering their synthesis, structures, luminescent properties, and applications in multi‐modal imaging and photodynamic therapy, highlighting their theranostic potential
Alain Tressaud +3 more
wiley +1 more source
Development and Application of Organic Sonosensitizers in Cancer Therapy
Aggregate, Volume 6, Issue 6, June 2025.This review provides a comprehensive overview of organic sonosensitizers employed in cancer treatment, describing their underlying mechanisms and structure‐activity relationship in terms of sonodynamic therapy. The significance of nanotechnology and combination therapy with other oncological modalities (photothermal therapy, photodynamic therapy, etc.)
Yuhan Ding +5 more
wiley +1 more source
Excited-State Intramolecular H Atom Transfer of Hypericin and Hypocrellin A Investigated by Fluorescence Upconversion [PDF]
, 1999 The excited-state intramolecular H atom transfer reaction occurring in hypericin and hypocrellin A is investigated by means of the fluorescence upconversion technique in a variety of solvents. Rising components of ∼10 ps, attributable to intramolecular H
Kraus, George +5 more
core
Sequencing and Functional Annotation of the Whole Genome of Shiraia bambusicola
G3: Genes, Genomes, Genetics, 2020 Shiraia bambusicola is a rare medicinal fungus found in China that causes bamboo plants to decay and die with severe infection. Hypocrellin, its main active ingredient, is widely used in several fields, such as medicine, agriculture, and food industry ...
Xiyi Ren +5 more
doaj +1 more source