The Unicorn Mouse: Cranial Lipoma in a B6.Cg Mouse
Intracranial lipomas, also called intracranial lipomatous hamartomas, have been reported in some strains of research mice, but are rare in C57BL6 strains.
Taylor A. Duncan, Kristi L. Helke
doaj +1 more source
Dynamics and ultrastructure of developmental cell fusions in the Caenorhabditis elegans hypodermis [PDF]
Cell fusions produce multinucleate syncytia that are crucial to the structure of essential tissues in many organisms [1-5]. In humans the entire musculature, much of the placenta, and key cells in bones and blood are derived from cell fusion. Yet the developmental fusion of cell membranes has never been directly observed and is poorly understood ...
Mohler, William A. +4 more
openaire +2 more sources
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Effects of dietary garlic (Allium sativum) meal on skin thickness and fat deposition in commercial broiler chickens [PDF]
Excessive deposition of fat in the skin of commercial chickens has major implications on human health. Garlic (Allium sativum) has been reported to have hypolipidaemic effect in animals.
O. Ogunlesi +3 more
doaj +1 more source
Bio‐Inspired Artificial Ionic Mechanoreceptor
A skin‐inspired artificial mechanoreceptor based on ionic interactions is presented for biomimetic tactile sensing. Pressure‐driven ionic redistribution within microfluidic channels generates a self‐powered electrical signal without external bias. The generated waveform exhibits mechanoreceptor‐like temporal features, including overshoot and undershoot,
Mohammad Akbari +4 more
wiley +1 more source
Biaxial tensile tests identify epidermis and hypodermis as the main structural elements of sweet cherry skin [PDF]
The skin of developing soft and fleshy fruit is subjected to considerable growth stress, and failure of the skin is associated with impaired barrier properties in water transport and pathogen defence.
Knoche, Moritz +5 more
core +1 more source
Making the Case for Organ‐on‐Chip Platforms in Long‐Acting Therapeutics Development
LATs release drug from a tissue‐resident depot over weeks to months, improving adherence, but their development is hampered by preclinical models that cannot reproduce the coupled tissue processes, sustained release, local microenvironment change, interstitial transport, immune and foreign‐body responses, and clearance that govern depot performance in ...
Charlie Gowans +7 more
wiley +1 more source
Comparative leaf anatomy of some species of Abies and Picea (Pinaceae)
A number of conifer species are still lacking anatomical data, which is significant because morphological and anatomical data are essential for systematic study.
Balkrishna Ghimire +3 more
doaj +1 more source
Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration
This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu +4 more
wiley +1 more source
Generation of the hypodermis in a vascularized three layered skin substitute
S.99Introduction: Patients with third degree burn wounds would benefit from a three-layer skin graft consisting of the epidermis, dermis and hypodermis.
Keck, M. +12 more
core +1 more source

