Results 61 to 70 of about 20,226 (265)

Depletion of the RNA‐Editing Enzyme ADAR1 Invigorates the Antitumor Immunity of NK Cells

Advanced Science, EarlyView.
ADAR1 is upregulated in NK cells from melanoma patients, impairing their function. Its loss enhances NK cell tumor infiltration and cytotoxicity in vitro and in vivo. Mechanistically, ADAR1 deficiency destabilizes CD38 mRNA to reduce its expression, thereby increasing NK cell mobility and killing, which nominates it as a therapeutic target for NK cell ...
Shuhan Chen, Di Lu, Rukang Liang, Weikeng Tan, Erming Zhao, Sihuang Wu, Xintong Li, Yulong Song, Miaojian Wan, Xiaoyuan Xie, Qi Zhang, Qiuli Liu   +11 more
wiley   +1 more source

The \u3cem\u3elet-7\u3c/em\u3e MicroRNA Family Members \u3cem\u3emir\u3c/em\u3e-48, \u3cem\u3emir\u3c/em\u3e-84, and mir-241 Function Together to Regulate Developmental Timing in \u3cem\u3eCaenorhabditis elegans\u3c/em\u3e [PDF]

, 2005
The microRNA let-7 is a critical regulator of developmental timing events at the larval-to-adult transition in C. elegans. Recently, microRNAs with sequence similarity to let-7 have been identified.
Abbott, Allison L., Alvarez-Saavedra, Ezequiel, Ambros, Victor R., Bartel, David P., Horvitz, H. Robert, Lau, Nelson C., Miska, Eric A.   +6 more
core   +1 more source

The Elephant Trunk Skin Inspires a Highly Sensitive and Deformable, Yet Robust, Armor Skin

Advanced Science, EarlyView.
The study presents the elephant trunk‐inspired armor skin with tactile sensing (ETATS). The ETATS architecture stretches and compresses while resisting puncture and tear, and it enables optical detection of pressure and lateral strain. Morphology‐based decoupling of strain and pressure paves the way to sensitive and deformable, yet robust, soft‐robotic
Jun Chang Yang, Petr Trunin, Behnam Kamare, Lucia Beccai   +3 more
wiley   +1 more source

Stage-Specific Timing of the microRNA Regulation of \u3cem\u3elin-28\u3c/em\u3e by the Heterochronic Gene \u3cem\u3elin-14\u3c/em\u3e in \u3cem\u3eCaenorhabditis elegans\u3c/em\u3e [PDF]

, 2017
In normal development, the order and synchrony of diverse developmental events must be explicitly controlled. In the nematode Caenorhabditis elegans, the timing of larval events is regulated by hierarchy of proteins and microRNAs (miRNAs) known as the ...
Abbott, Allison L., Moss, Eric G., Romens, Mitchell A., Tsialikas, Jennifer   +3 more
core   +1 more source

Patient‐Mounted Neuro Optical Coherence Tomography for Targeted Minimally Invasive Micro‐Resolution Volumetric Imaging in Brain In Vivo

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
Herein, a patient‐mounted neuro optical coherence tomography system that integrates a 5 degrees‐of‐freedom skull‐mounted robot (Skullbot) with a 0.6 mm neuroendoscope for targeted, minimally invasive deep brain imaging, is developed. The system offers high‐resolution imaging with precise deployment, demonstrated through successful tumor imaging in a ...
Chao Xu, Zhiwei Fang, Huxin Gao, Tinghua Zhang, Tao Zhang, Peng Liu, Hongliang Ren, Wu Yuan   +7 more
wiley   +1 more source

Dynamics of 131I accumulation and formation of doses in organs and tissues of the laboratory rats by prolonged oral intake

Ядерна фізика та енергетика, 2015
The kinetics of 131I and dose formation in organs and tissues of laboratory Wistar rats with prolonged exposure was investigated. The methodical approach to the identification of variables that allows to describe the function of uptake in the thyroid (TG)
I. P. Drozd, O. A. Sova, A. I. Lypska
doaj  

Repulsive guidance molecule acts in axon branching in Caenorhabditis elegans

Scientific Reports, 2021
Repulsive guidance molecules (RGMs) are evolutionarily conserved proteins implicated in repulsive axon guidance. Here we report the function of the Caenorhabditis elegans ortholog DRAG-1 in axon branching.
Kaname Tsutsui, Hon-Song Kim, Chizu Yoshikata, Kenji Kimura, Yukihiko Kubota, Yukimasa Shibata, Chenxi Tian, Jun Liu, Kiyoji Nishiwaki   +8 more
doaj   +1 more source

Computational Analysis of a Multi-Layered Skin and Cardiac Pacemaker Model Based on Neural Network Approach

Sensors, 2022
The presented study discusses the possible disturbing effects of the electromagnetic field of antennas used in mobile phones or WiFi technologies on the pacemaker in the patient’s body.
Zuzana Psenakova, Maros Smondrk, Jan Barabas, Mariana Benova, Rafał Brociek, Agata Wajda, Paweł Kowol, Salvatore Coco, Grazia Lo Sciuto   +8 more
doaj   +1 more source

EMG‐Driven Telemetry and Inference System for Fish: Pose Reconstruction and Flow Sensing

Advanced Intelligent Systems, EarlyView.
This work introduces an electromyography (EMG)‐driven telemetry framework that reconstructs body pose and infers hydrodynamic conditions in freely swimming fish. A custom 16‐channel archival system records intramuscular EMG, enabling deep‐learning models to decode joint kinematics, classify flow regimes, and reveal channel‐efficient sensing strategies.
Rahdar Hussain Afridi, Waqar Hussain Afridi, Muhammad Hamza, Ahsan Tanveer, Mingxin Wu, Xingwen Zheng, Liang Li, Guangming Xie   +7 more
wiley   +1 more source

Cytological and molecular description of Hamiltosporidium tvaerminnensis gen. et sp. nov., a microsporidian parasite of Daphnia magna, and establishment of Hamiltosporidium magnivora comb. nov. [PDF]

, 2011
We describe the new microsporidium Hamiltosporidium tvaerminnensis gen. et sp. nov. with an emphasis on its ultrastructural characteristics and phylogenetic position as inferred from the sequence data of SSU rDNA, alpha-and beta-tubulin.
DIETER EBERT, DOMINIK REFARDT, Ebert, Ebert, Green, Hazard, Hostounský, J. I. RONNY LARSSON, Jírovec, KAREN LUISA HAAG, Larsson, Larsson, Ormières, Romeis, Vávra   +14 more
core   +1 more source