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AACN Advanced Critical Care, 1992
Optimal control of blood glucose requires a balance of diet, exercise, and in some cases, medications. Many factors can cause a state of imbalance, resulting in extremes of glucose control. Hypoglycemia is defined generally as a blood glucose level lower than 50 mg/dL.
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Optimal control of blood glucose requires a balance of diet, exercise, and in some cases, medications. Many factors can cause a state of imbalance, resulting in extremes of glucose control. Hypoglycemia is defined generally as a blood glucose level lower than 50 mg/dL.
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Transient Hypoglycemic Hemiplegia
Archives of Internal Medicine, 1964In this paper, the clinical features and the theories of pathogenesis of transient hypoglycemic hemiplegia will be summarized. Report of a Case History. —A 22-year-old white male was hosiptalized because of the sudden development of hemiplegia. He was a ketosis-prone diabetic of nine years' duration.
B M, MONTGOMERY, C A, PINNER
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Seminars in Neonatology, 2001
Hypoglycemia frequently occurs in newborn infants who previously have suffered asphyxia, who are offspring of diabetic mothers, or who are low birthweight for gestational age (IUGR). Many infants who are hypoglycemic do not exhibit clinical manifestations, while others are symptomatic and at risk for the occurrence of permanent brain damage.
R C, Vannucci, S J, Vannucci
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Hypoglycemia frequently occurs in newborn infants who previously have suffered asphyxia, who are offspring of diabetic mothers, or who are low birthweight for gestational age (IUGR). Many infants who are hypoglycemic do not exhibit clinical manifestations, while others are symptomatic and at risk for the occurrence of permanent brain damage.
R C, Vannucci, S J, Vannucci
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Primary Care: Clinics in Office Practice, 1977
Oral agents should not be used in the treatment of patients with asymptomatic maturity-onset diabetes. The indication for sulfonylureas is symptomatic maturity-onset diabetes or excessive hyperglycemia--fasting blood sugar over 300 mg per 100 ml--in the elderly patient who cannot or will not take insulin. The use of biguanides cannot be recommended.
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Oral agents should not be used in the treatment of patients with asymptomatic maturity-onset diabetes. The indication for sulfonylureas is symptomatic maturity-onset diabetes or excessive hyperglycemia--fasting blood sugar over 300 mg per 100 ml--in the elderly patient who cannot or will not take insulin. The use of biguanides cannot be recommended.
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Metabolic Brain Disease, 2004
Hypoglycemia was long considered to kill neurons by depriving them of glucose. We now know that hypoglycemia kills neurons actively from without, rather than by starvation from within. Hypoglycemia only causes neuronal death when the EEG becomes flat. This usually occurs after glucose levels have fallen below 1 mM (18 mg/dl) for some period, depending ...
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Hypoglycemia was long considered to kill neurons by depriving them of glucose. We now know that hypoglycemia kills neurons actively from without, rather than by starvation from within. Hypoglycemia only causes neuronal death when the EEG becomes flat. This usually occurs after glucose levels have fallen below 1 mM (18 mg/dl) for some period, depending ...
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New England Journal of Medicine, 1989
ORAL hypoglycemic agents are commonly prescribed drugs. In the United States they account for about 1 percent of all prescriptions.1 This review discusses the pharmacology, mechanisms of action, ef...
John A. Oates +2 more
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ORAL hypoglycemic agents are commonly prescribed drugs. In the United States they account for about 1 percent of all prescriptions.1 This review discusses the pharmacology, mechanisms of action, ef...
John A. Oates +2 more
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Medical Clinics of North America, 1988
The sulfonylureas remain the most important oral agents, although their chronic hypoglycemic actions are still unexplained and the evidence on their relative efficacy is inconclusive. Data on relative safety suggest that chlorpropamide is the most toxic sulfonylurea but glyburide causes dangerous hypoglycemia as often as chlorpropamide.
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The sulfonylureas remain the most important oral agents, although their chronic hypoglycemic actions are still unexplained and the evidence on their relative efficacy is inconclusive. Data on relative safety suggest that chlorpropamide is the most toxic sulfonylurea but glyburide causes dangerous hypoglycemia as often as chlorpropamide.
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The management of the hypoglycemic patient
World Journal of Surgery, 1982AbstractOrganic hypoglycemia may be caused by an insulinoma. This is a rare tumor, multiple in about 10% and malignant in about 10% of cases. Multiplicity is particularly likely when insulinoma occurs as part of the MEN 1 syndrome. When a patient exhibits Whipple's triad, synchronous blood sugar and insulin estimations must be made, and repeated during
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Hypoglycemic Action of Tryptophan
Diabetes, 1973These studies were designed to define the mechanism by which the tryptophan metabolite, quinolinic acid, blocks gluconeogenesis and to determine the role it plays in influencing this process under physiologic and pathologic conditions. An alteration in the level of gluconeogenic intermediates occurred at a quinolinic acid content of 43 ng.
H G, McDaniel, B R, Boshell, W J, Reddy
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Hypoglycemic Peripheral Neuropathy
Archives of Neurology, 1969PERIPHERAL neuropathy is a rare finding in spontaneous hypoglycemia, and only 22 patients have been reported in the literature (Table 1). 1-12 The purpose of this communication is to report two additional cases and to analyze the clinical presentation of peripheral neurological symptoms that occasionally accompany spontaneous hypoglycemia.
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