Results 131 to 140 of about 57,360 (167)

New hypoglycemic agents and the kidney: what do the major trials tell us? [PDF]

F1000Res, 2018
Smyth B, Perkovic V.
europepmc   +1 more source

Dose–Response Effect of Glucagon on Glucose, Beta‐Cell Secretion and Metabolism in Healthy Individuals

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aim Glucagon is a key regulator of glucose and energy metabolism, yet the dose–response effects of glucagon on markers of metabolism in humans are not fully characterised. We investigated the dose‐dependent effects of glucagon on glucose metabolism, β‐cell secretion and markers of hepatic metabolism in healthy adults.
Sophie Betty Brock, Nina Lerberg Hansen, Elvar Már Sturlaugsson Jóhönnuson, Sasha Alexandra Sampson Kjeldsen, Nicolai J. Wewer Albrechtsen   +4 more
wiley   +1 more source

Assessing hypoglycemia frequency using flash glucose monitoring in older Japanese patients with type 2 diabetes receiving oral hypoglycemic agents. [PDF]

Geriatr Gerontol Int, 2019
Abe H, Shikuma J, Suwanai H, Sano K, Okumura T, Kan K, Takahashi T, Miwa T, Suzuki R, Odawara M.   +9 more
europepmc   +1 more source

Impact of Time of Injection on the Efficacy and Safety of iGlarLixi Versus IDegAsp in Chinese People With Type 2 Diabetes: Exploratory Analysis of the Soli‐D Study

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims To compare the efficacy and safety of the fixed‐ratio combination of insulin glargine 100 U/mL plus lixisenatide (iGlarLixi) with premixed insulin degludec plus insulin aspart (IDegAsp) according to the injection time of IDegAsp. Materials and Methods The 24‐week, multicentre, randomised, open‐label Soli‐D study enrolled Chinese adults ...
Xin Li, Juan Wang, Tong Liu, Agustina Alvarez, Felipe Lauand, Lydie Melas‐Melt, Lei Kang, Qin Du, Ming Liu   +8 more
wiley   +1 more source

Effect of hypoglycemic agents on survival outcomes of lung cancer patients with diabetes mellitus: A meta-analysis. [PDF]

Medicine (Baltimore), 2018
Xin WX, Fang L, Fang QL, Zheng XW, Ding HY, Huang P.   +5 more
europepmc   +1 more source

The Effects of Combined Antihypertensive and Antidiabetic Therapies on Cardiovascular Outcomes: A Systematic Review and Meta‐Analysis

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Hypertension and diabetes frequently coexist, yet the net clinical impact of intentionally combining antihypertensive (AHTN) and antidiabetic (ADA) therapies on cardiovascular (CV) outcomes is uncertain. Here we quantified the effects of AHTN and ADA co‐therapy on CV and blood pressure (BP)/heart rate (HR) outcomes.
Wan Chin Hsieh, Brandon Michael Henry, István Édes   +2 more
wiley   +1 more source

Association between use of oral hypoglycemic agents in Japanese patients with type 2 diabetes mellitus and risk of depression: A retrospective cohort study. [PDF]

Pharmacol Res Perspect, 2019
Akimoto H, Tezuka K, Nishida Y, Nakayama T, Takahashi Y, Asai S.   +5 more
europepmc   +1 more source

Patterns and Trends of Glucose‐Lowering Therapy in Alzheimer's Disease and Related Dementias

Diabetes, Obesity and Metabolism, EarlyView.
Huilin Tang, Bingyu Zhang, Yiwen Lu, Ying Lu, Anastassia Amaro, Yuan Lu, David A. Wolk, Yong Chen   +7 more
wiley   +1 more source

Real‐World Effectiveness and 12‐Month Persistence of a Semaglutide‐Supported Digital Weight‐Loss Service: A Retrospective Cohort Study in Germany

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aim To evaluate the 12‐month effectiveness and patient persistence of a semaglutide‐supported digital weight‐loss service (DWLS) in a real‐world German cohort. Methods This retrospective study analysed 4535 patients who initiated the Juniper Germany DWLS. Primary endpoints included 12‐month medication and data submission adherence (receiving ≥ 
Louis Talay, Jason Hom, Marilyn Tan, Neera Ahuja   +3 more
wiley   +1 more source

Glycaemic Control by Sociodemographic Factors in Adults With Type 1 Diabetes in England: Trends From 2007–2008 to 2023–2024

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims This study evaluated trends in glycaemic control in adults with Type 1 diabetes in England from 2007–2008 to 2023–2024, stratified by age, sex, ethnicity and socioeconomic deprivation. Materials and Methods Adults aged ≥ 20 years from the National Diabetes Audit were analysed.
Muhammad Saleem Khan, Jonathan Valabhji, Naveed Sattar, Helen Murphy, Fulya Mehta, Partha Kar, Clare Hambling, Kamlesh Khunti, Garry D. Tan, Naomi Holman   +9 more
wiley   +1 more source