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2017
Three oral hypoglycemic agents have been studied for use in pregnancy: metformin, glyburide, and acarbose. This chapter is a review of the literature regarding the use of these three agents during pregnancy including a discussion of available formulations and dosing.
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Three oral hypoglycemic agents have been studied for use in pregnancy: metformin, glyburide, and acarbose. This chapter is a review of the literature regarding the use of these three agents during pregnancy including a discussion of available formulations and dosing.
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Pharmacotherapy of Oral Hypoglycemic Agents
Clin-Alert, 1973The use of sulfonylurea in conjunction with a diet and exercise regimen continues to be the primary treatment modality for obese type II diabetics in the United States. These agents work to lower plasma glucose by several proposed mechanisms. Pancreatic mechanisms of action improve efficiency of the islet beta cells, and extrapancreatic mechanisms of ...
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Insulin and Oral Hypoglycemic Agents
1986About 100 years have elapsed since the classic experiments of von Mering and Minkowski demonstrated that pancreatomized dogs exhibited signs and symptoms resembling those seen in diabetes mellitus. The pioneering efforts of Banting and Best revealed that pancreatic extracts could sustain the life of patients suffering from severe diabetes, thereby ...
Edward J. Keenan, John A. Thomas
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Phytochemicals as potential hypoglycemic agents
2000Diabetes mellitus is a chronic metabolic disorder characterized by a high blood glucose concentration (hyperglycemia) which is due to insulin deficiency and/or insulin resistance. Hyperglycemia occurs because the liver and skeletal muscle cannot store glycogen and the tissues are unable to take up and utilize glucose.
S. S. Lamba +4 more
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Clinical use of oral hypoglycemic agents
American Journal of Health-System Pharmacy, 1976The pharmacology, mechanism of action, indications, interactions and clinical effectiveness of oral hypoglycemic agents, specifically the sulfonylureas and biguanides, are reviewed. The use of these agents is discussed in view of the findings of the University Group Diabetes Program study.
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The Hypoglycemic Agents-Their Interactions*
Journal of the American Pharmaceutical Association (1961), 1970openaire +3 more sources