Results 31 to 40 of about 3,268,533 (214)

Repositioning of Verrucosidin, a purported inhibitor of chaperone protein GRP78, as an inhibitor of mitochondrial electron transport chain complex I. [PDF]

, 2013
Verrucosidin (VCD) belongs to a group of fungal metabolites that were identified in screening programs to detect molecules that preferentially kill cancer cells under glucose-deprived conditions.
Chen, Thomas C, Gonzalez, Reyna, Hofman, Florence M, Louie, Stan G, Pao, Peng-Wen, Pirrung, Michael C, Schönthal, Axel H, Sharma, Natasha, Thomas, Simmy   +8 more
core   +2 more sources

Bornyl-Containing Derivatives of Benzyloxyphenylpropanoic Acid as FFAR1 Agonists: In Vitro and In Vivo Studies

Pharmaceutics, 2023
Type 2 diabetes mellitus (T2DM) is one of the most common chronic diseases worldwide. Several classes of hypoglycemic drugs are used to treat it, but various side effects limit their clinical use.
Darya A. Pon’kina, Sergey O. Kuranov, Mariya K. Marenina, Yulia V. Meshkova, Nataliya A. Zhukova, Mikhail V. Khvostov, Olga A. Luzina, Tatiana G. Tolstikova, Nariman F. Salakhutdinov   +8 more
doaj   +1 more source

Comparison of SGLT2 inhibitors with DPP-4 inhibitors combined with metformin in patients with acute myocardial infarction and diabetes mellitus

Cardiovascular Diabetology, 2023
Background Although sodium-glucose cotransporter 2 inhibitors (SGLT2i) have demonstrated cardiovascular benefits in patients with type 2 diabetes mellitus, real-world evidence regarding their benefits to diabetic patients with acute myocardial infarction
Young Sang Lyu, Seok Oh, Jin Hwa Kim, Sang Yong Kim, Myung Ho Jeong   +4 more
doaj   +1 more source

Post-Transplant Diabetes: Prevalence, Risk, and Management Challenges

Dubai Diabetes and Endocrinology Journal, 2022
The prevalence of diabetes and diabetic nephropathy is increasing, especially in middle eastern countries. Many patients reach end-stage renal disease and either start dialysis or consider preemptive transplantation.
Alaaeldin M.K. Bashier, Dileep Kumar, Fakhriya J. Alalawi, Hind Al Nour, Amna Khalifa Al Hadari, Azza Abdulaziz Bin Hussain   +5 more
doaj   +1 more source

The glycemic elemental profile of trichosanthes dioica: a LIBS-based study [PDF]

, 2010
The scientific evaluation of the antidiabetic efficacy of aqueous extract of Trichosanthes dioica fruits on streptozotocin-induced diabetic rats is being presented. The graded doses of the extract, viz., 500, 750, 1,000, and 1,250 mg/kg body weight (bw),
Bicanic, D.D., Chatterji, S., Rai, N.K., Rai, P.K., Watal, G.   +4 more
core   +2 more sources

Synthesis of Rosmarinic Acid Amides as Antioxidative and Hypoglycemic Agents.

Journal of Natural Products, 2019
Type 2 diabetes mellitus (T2DM) is an important metabolic disorder for which there is an urgent need for new antidiabetic drugs. α-Glucosidase inhibition is an established protocol for T2DM therapy.
Nunzio Cardullo, G. Catinella, Giuseppe Floresta, V. Muccilli, S. Rosselli, A. Rescifina, M. Bruno, C. Tringali   +7 more
semanticscholar   +1 more source

Second-line Medication Preference in Patients with Type 2 Diabetes: a Study Based on a Discrete Choice Experiment [PDF]

Zhongguo quanke yixue
Background With the continuous improvement of diabetes prevention and treatment strategies, clinical guidelines recommend first-line hypoglycemic agents while emphasizing a "patient-centered", and the selection of appropriate second-line ...
LIU Zhigang, LIU Shimeng, ZHENG Lyuyun, XUE Wenjing, CAO Chenchen, LIU Jing, CHEN Yingyao
doaj   +1 more source

Glycated albumin and hemoglobin A1c levels and cause-specific mortality by patients’ conditions among hemodialysis patients with diabetes: a 3-year nationwide cohort study

BMJ Open Diabetes Research & Care, 2020
Introduction Differences in mortality and cause-specific mortality rates according to glycated albumin (GA) and hemoglobin A1c (HbA1c) levels among dialysis patients with diabetes based on hypoglycemic agent use and malnutrition status remain unclear ...
Takayuki Hamano, Masanori Abe, Atsushi Wada, Kenmei Takaichi, Shigeru Nakai, Ikuto Masakane, Kosaku Nitta   +6 more
doaj   +1 more source

Nephroprotection by Hypoglycemic Agents: Do We Have Supporting Data? [PDF]

J Clin Med, 2015
José Luis Górriz, Javier Nieto, Juan F. Navarro‐González, Pablo Molina, Alberto Martínez‐Castelao, Luis Pallardó   +5 more
openalex   +2 more sources

Oral hypoglycemic agents: do the ends justify the means? [PDF]

Matern Health Neonatol Perinatol, 2015
Oded Langer
openalex   +2 more sources