Results 121 to 130 of about 79,496 (316)
American Journal of Medical Genetics Part A, Volume 200, Issue 2, Page 291-299, February 2026.ABSTRACT Heterozygous pathogenic variants in TBX3 cause Ulnar‐Mammary syndrome (UMS). The phenotype is classically characterized by upper limb defects, apocrine/mammary gland hypoplasia, hypogonadism, and various midline defects. However, the clinical spectrum is highly variable, and some individuals may present with a mild or atypical presentation ...
Ziv Halperin, Karin Weiss
wiley +1 more source
Neurogenesis and the Epigenetic Landscape: Role of Histone Modifications and Chromatin Remodeling
Brain and Behavior, Volume 16, Issue 2, February 2026.Histone methylation and acetylation modulate gene expression by inducing chromatin condensation or relaxation, which in turn regulates transcriptional activity and impacts neurogenesis. ABSTRACT Aims The purpose of this review is to examine how epigenetic regulation particularly chromatin modification and histone methylation controls gene expression ...
Degisew Yinur Mengistu +1 more
wiley +1 more source
ODP401 A new FGFR1 mutation causing Idiopathic Hypogonadotropic Hypogonadism and Polydactyly [PDF]
, 2022 Luis Borges Espinosa +2 more
openalex +1 more source
Targeted Next‐Generation Sequencing of the Leptin‐Melanocortin Pathway in Severe Obesity
Obesity, Volume 34, Issue 2, Page 499-511, February 2026.ABSTRACT Objective Pathogenic variants in five established leptin‐melanocortin pathway genes (LEP, LEPR, MC4R, PCSK1, POMC) are associated with severe early‐onset obesity and are targets for emerging treatments. However, these variants are rare in these patients, suggesting the involvement of additional genes interacting with this pathway. Methods Next‐
Nathan Faccioli +12 more
wiley +1 more source
Hypogonadism precedes liver feminization in chronic alcohol-fed male rats [PDF]
, 2000 Staša Tadić +3 more
openalex +1 more source
Andrology, Volume 14, Issue 2, Page 398-410, February 2026.Abstract Background WFS1 spectrum disorder, also known as Wolfram syndrome (WS) is an ultra‐rare (<1:500,000; ORPHA: 3463) monogenic (OMIM #222300) progressive neuroendocrine and neurodegenerative disorder, characterised by early‐onset insulin‐dependent diabetes, optic atrophy, central diabetes insipidus and sensi‐neuronal deafness.
Julia Rohayem +6 more
wiley +1 more source
Andrology, Volume 14, Issue 2, Page 377-384, February 2026.Abstract Background Erectile dysfunction in people living with HIV is a multifactorial disease, but the role of penile vascular status assessed by dynamic penile color Doppler echography is underexplored. Objectives This study assessed penile vascular status in young males living with HIV experiencing erectile dysfunction, comparing them to HIV ...
Giorgio Tiecco +9 more
wiley +1 more source
The aging male: investigation, treatment and monitoring of late-onset hypogonadism in males [PDF]
, 2006 Androgen deficiency in the aging male has become a topic of increasing interest and debate throughout the world. The demographics clearly demonstrate the increasing percentage of the population that is in the older age groups.
Behre, Hermann M. +11 more
core
Andrology, Volume 14, Issue 2, Page 516-527, February 2026.Abstract Background Rheumatoid arthritis (RA) is an inflammatory disease triggered by chronic and systemic activation of the immune system, with consequences for male fertility. However, the influence of RA on sexual accessory glands remains poorly investigated.
Thamires Miyako Ito Sigole +5 more
wiley +1 more source
ClinicoEconomics and Outcomes Research, 2021 Sandy Yeo,1 Katsiaryna Holl,2 Nicolás Peñaherrera,3 Ulrike Wissinger,3 Kate Anstee,4 Robin Wyn4 1Real World Evidence, Bayer (South East Asia) Pte Ltd, Singapore; 2Real World Evidence, Bayer, Germany; 3Global Medical Affairs, Bayer, Berlin ...
Yeo S +5 more
doaj