Results 141 to 150 of about 72,413 (261)

Kisspeptin as a test of hypothalamic dysfunction in pubertal and reproductive disorders

Andrology, Volume 14, Issue 4, Page 1002-1016, May 2026.
Abstract The hypothalamic–pituitary–gonadal axis is regulated by the gonadotropin‐releasing hormone pulse generator in the hypothalamus. This is comprised of neurons that secrete kisspeptin in a pulsatile manner to stimulate the release of GnRH, and, in turn, downstream gonadotropins from the pituitary gland, and subsequently sex steroids and ...
Aureliane C. S. Pierret, Aaran H. Patel, Elisabeth Daniels, Alexander N. Comninos, Waljit S. Dhillo, Ali Abbara   +5 more
wiley   +1 more source

Defining Acquired Hypothalamic Obesity: An Expert Call for Unified Diagnosis and Therapeutic Action

Diabetes, Obesity and Metabolism, EarlyView.
Hanneke M. van Santen, Ashley H. Shoemaker, Mehul T. Dattani, Christian L. Roth, Mohamad Maghnie, Kevin C. J. Yuen, Christine Poitou, Hermann L. Müller   +7 more
wiley   +1 more source

Luteinizing hormone receptor knockout mouse: What has it taught us?

Andrology, Volume 14, Issue 4, Page 1017-1028, May 2026.
Abstract Luteinizing hormone (LH), along with its agonist choriongonadotropin (hCG) in humans, is the key hormone responsible for the tropic regulation of the gonadal function. LH and hCG act through their cognate receptor, the luteinizing hormone/choriongonadotropin receptor (LHCGR; more appropriately LHR in rodents lacking CG), located in the testis ...
Ilpo T. Huhtaniemi
wiley   +1 more source

Folding, misfolding, and regulation of intracellular traffic of G protein‐coupled receptors involved in the hypothalamic–pituitary–gonadal axis

Andrology, Volume 14, Issue 4, Page 978-991, May 2026.
Abstract Background G protein‐coupled receptors are a large and functionally diverse family of membrane receptors involved in a number of biological processes. Like other proteins, G protein‐coupled receptors need to be properly folded in order to traffic to the plasma membrane and interact with agonist.
Alfredo Ulloa‐Aguirre, Ross C. Anderson, Teresa Zariñán, Rubén Gutiérrez‐Sagal, Eduardo Jardón‐Valadez, Claire L. Newton   +5 more
wiley   +1 more source

Pharmacogenetics of follicle‐stimulating hormone action in the male

Andrology, Volume 14, Issue 4, Page 1064-1072, May 2026.
Abstract Male factor infertility (MFI) is involved in half of the cases of couple infertility. The follicle‐stimulating hormone (FSH) therapy is considered efficient to improve semen parameters and pregnancy rate in patients with idiopathic MFI, following the lesson learned from hypogonadotropic hypogonadism.
Andrea Graziani, Giuseppe Grande, Raffele Scafa, Riccardo Selice, Andrea Garolla, Maria Santa Rocca, Cinzia Vinanzi, Alberto Ferlin   +7 more
wiley   +1 more source

Bleeding Disorders in Children With Genetic Diseases: A Narrative Review

Acta Paediatrica, Volume 115, Issue 5, Page 1015-1024, May 2026.
ABSTRACT Aim The lack of data on bleeding risk assessment in children with genetic diseases is concerning given their increased care needs and risk of haemorrhagic complications compared to the general population. Identification of haemostatic disorders is crucial for implementing preventive measures and mitigating bleeding risk.
Raphaelle Cagol, Mariam Sbeity Barakat, Marjolaine Willems, Tasnime Akbaraly, Biron‐Andreani Christine, Isabelle Diaz, Alexandre Theron   +6 more
wiley   +1 more source

Hypogonadism [PDF]

, 2020
Jill C. Cash, Mellisa A. Hall
openaire   +2 more sources

Guideline of guidelines: Peyronie's disease

BJU International, Volume 137, Issue 5, Page 770-782, May 2026.
Objective To compare major Peyronie's disease (PD) guidelines, highlight key similarities and differences among panel recommendations, and identify areas requiring further research. Methods An extensive review was conducted to analyse and compare diagnostic and treatment recommendations from publicly available guidelines published by the American ...
Francesco Chierigo, Giuseppe Fallara, Marco Tozzi, Andrea Salonia, Matteo Ferro, Hussain M Alnajjar, Asif Muneer, Karl H. Pang   +7 more
wiley   +1 more source

Sexual dysfunction is highly prevalent in patients with active perianal fistulizing Crohn's disease: Outcomes from a large national prospective cohort study

Colorectal Disease, Volume 28, Issue 5, May 2026.
Abstract Background Sexual function is one of the determinants of quality of life (QoL) and is prevalent in approximately half of the patients with inflammatory bowel disease. However, the sexual function in patients with perianal fistulizing Crohn's disease (pCD) needs to be further elucidated.
Michiel T. J. Bak, Annemarie C. de Vries, Laurents P. S. Stassen, Moniek M. ter Kuile, Andrea E. van der Meulen – de Jong, Oddeke van Ruler, on behalf of the ALERT‐CD study group, the Dutch Initiative on Crohn and Colitis and the Dutch Initiative on Crohn and Colitis—Surgery, Michiel T.J. Bak, Laurents P.S. Stassen, Christianne J. Buskens, Aagje M. Pronk, Jarmila D.W. van der Bilt, Liesbeth J. Munster, Nanne K.H. de Boer, Krisztina B. Gecse, Robert‐Jan B. Pierik, Caroline D.M. Witjes, Claire E. Fitzpatrick, Stephanie O. Breukink, Marieke J. Pierik, Loes H.C. Nissen, Emiel G.G. Verdaasdonk, Lennard P.L. Gilissen, Johanne G. Bloemen, Wout G.N. Mares, Gabie M. de Jong, Marjolein Sikkema, David D.E. Zimmerman, Dominique Bierens‐Peters, Vincent de Jonge, Robert M. Smeenk, Bindia J. Jharap, Evelien de Witte, Mariëlle Romberg‐Camps, Alexander G.L. Bodelier, Ninos Ayez, Xander G. Vos, Margot A. van Herwaarden, Suzan Bos‐Poliste, Fleur A. Indemans, Petra G. A. van Boeckel, Michiel D. Voskuil, Egbert‐Jan van der Wouden, Annette D. van Dalsen, Saskia Willemsen‐Maas, Sigrid Vandebosch, Els van Dessel, Rob P.R. Adang, Joop L.M. Konsten, Sanne M. van Aalten, Margriet H. Wobbes, Esmerij P. van der Zanden, Sanne C. Veltkamp, Bareld B. Pultrum, Rinze W. F. ter Steege, Merel M. Tielemans, Mike van der Have, Abraham T. Zuur, Pieter C.J. ter Borg, Henri Braat, Tjeerd S. Aukema, Rogier J. L. Stuyt, Charles C. van Rossem, K. Evelyne Verweij, Justin Y. van Oostendorp, Ingrid Han‐Geurts, Patricia van Tongeren, Johannes A. Govaert, Sander van der Marel, Carmen S. Horjus, Jeroen M. Jansen, Sita V. Jansen, Alexander L.A. Bloemendaal, Rachel L. West, Robert T.J. Kortekaas, Koen C.M.J. Peeters, Andrea E. van der Meulen‐de Jong, Fiona D.M. van Schaik, Milan C. Richir, Koen W. van Dongen, Marjolijn Duijvestein, Dianne G. Bouwknegt, Froukje J. Hoogenboom, Marijn C. Visschedijk, Annemarie. C. de Vries, Oddeke van Ruler   +86 more
wiley   +1 more source

Recovery From Anorexia Nervosa: A Concept Analysis

Journal of Advanced Nursing, Volume 82, Issue 5, Page 4840-4875, May 2026.
ABSTRACT Aim Despite decades of research, we still know surprisingly little about how best to bring about lasting recovery from anorexia nervosa (AN). Furthermore, there is a lack of consensus in the research and treatment communities about what constitutes recovery from AN, or whether “recovery” is even an appropriate term to use in this context.
Sarah Ramsay, Kendra Allison
wiley   +1 more source