Results 161 to 170 of about 72,413 (261)
Middle‐aged/older (MA/O) men with low testosterone have greater age‐related vascular endothelial dysfunction than MA/O with normal testosterone. This study highlights the potential role of mitochondrial dysfunction and reduced sirtuin 3, a key modulator of mitochondrial function and oxidative stress, in accelerated vascular aging in MA/O men with low ...
Branden L. Nguyen +14 more
wiley +1 more source
Induction of puberty in hypogonadal forms of primary amenorrhoea: current evidence and future perspectives. [PDF]
Profka E +6 more
europepmc +1 more source
Low Testosterone in Men With Type 2 Diabetes: The Role of Estrogen Excess and Aromatase Activity
ABSTRACT Objective Low testosterone is common in men with type 2 diabetes and is associated with adverse metabolic outcomes. Our objective was to identify factors associated with low total and calculated free testosterone (CFT) in men with type 2 diabetes, with a focus on relative estrogen excess and subcutaneous adipose aromatase expression.
Nyo Nyo Z. Tun +2 more
wiley +1 more source
Management of infertility in women with hypothalamic hypogonadotropic hypogonadism: an expert opinion. [PDF]
Robin G +6 more
europepmc +1 more source
Mitochondrial DNA Depletion Syndrome 1 (MTDPS1)—A Novel Cause of Premature Ovarian Insufficiency
We describe a woman with MNGIE due to a novel homozygous TYMP nonsense variant and propose MNGIE as the cause of her premature ovarian insufficiency—a rarely reported association—highlighting the need to consider mitochondrial disease in unexplained POI, especially in atypical, consanguineous presentations. ABSTRACT Mitochondrial DNA depletion syndrome
Michael Matheou +3 more
wiley +1 more source
Male hypogonadism in patients on maintenance hemodiafiltration: prevalence and therapeutic effect. [PDF]
Carvalho MS +7 more
europepmc +1 more source
Abstract The chemokine network in the microenvironment of pituitary neuroendocrine tumours (PitNETs) may modulate tumour biology, aggressiveness, and treatment responses. We aimed to study the role of various chemokines and chemokine receptors in defining PitNET phenotype and clinical outcomes.
Ana Luísa Silva +13 more
wiley +1 more source
Midbrain Malformation Presenting With Hypogonadism and Short Stature. [PDF]
Sai Ramya V +3 more
europepmc +1 more source
Abstract Menopause is the time when a woman transitions from the reproductive stage of life to the non‐reproductive state. It is characterised by significant hormonal changes, which can affect a woman's physical, emotional, mental and social well‐being.
Irene Bretón Lesmes +7 more
wiley +1 more source

