Results 101 to 110 of about 24,444 (242)
Food Science &Nutrition, Volume 14, Issue 6, June 2026.The present studies of network pharmacology, molecular docking and molecular dynamics simulation indicated that liensinine might ameliorate oxidative damage to vascular endothelium (ODVE) by regulating the targets of Nrf2, which is encoded by the NFE2L2 gene. Then the in vitro study further showed that liensinine exhibited an obvious protection against
Feng Gao +7 more
wiley +1 more source
Hypolipidemic activity of Piper betel in high fat diet induced hyperlipidemic rat
, 2014 Objective: To evaluate the hypolipidemic effect of Piper betel (P. betel) in high fat diet induced hyperlipidemia rat. Methods: The methanol leaf extract was tested for hypolipidemic effect in the albino rats at the selected optimum dosage of 250 mg/kg ...
Ernest David +2 more
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Health Science Reports, Volume 9, Issue 6, June 2026.ABSTRACT Background and Aims Biomarkers of biological aging, including homeostatic dysregulation (HD), Klemera–Doubal method biological age (KDM‐BA), and phenotypic age (PA), provide multidimensional quantification of the aging process. Although insulin resistance correlates with accelerated aging, the connection between biological aging and the ...
Mengjie Zhao +5 more
wiley +1 more source
Indole-Based Fibrates as Potential Hypolipidemic and Antiobesity Agents
, 2016 Hypolipidemic and antiobesity effects of the newly synthesized indole-based fibrates were evaluated in Triton WR-1339 and high fat diet (HFD)-induced hyperlipidemic rats.
Bhanu Shankar Singh (2100523) +5 more
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PlantsDiabetes mellitus is a chronic, degenerative, and multifactorial disease characterized by hyperglycemia, and at least 537 million people suffered from diabetes in 2021.
Juan David Bermudes-Contreras +4 more
doaj +1 more source
C4 Functionalization of the Isoquinoline Core via Oxidative Radical Substitution
ChemistrySelect, Volume 11, Issue 21, 4 June 2026.The isoquinoline ring can be easily functionalized at C‐4 through a radical‐oxidative substitution process. The resulting products can be readily cyclized under basic conditions, facilitating the construction of pyranones fused to the isoquinoline scaffold. ABSTRACTIn this work, we report a straightforward synthetic procedure that enables the selective
Oscar Coral +2 more
wiley +1 more source
, 2012 Z-Guggulsterone is a major ingredient in the Indian traditional hypolipidemic remedy guggul. A study in mice has established that its hypolipidemic effect involves the farnesoid X receptor (FXR), presumably by acting as an antagonist of this receptor. It
Yang, Jian +7 more
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Journal of Food Science, Volume 91, Issue 6, June 2026.ABSTRACT Peanuts are among the most widely produced nuts globally, generating greater quantities of shell residues than other nut by‐products, thereby representing a highly abundant source of lignocellulosic fiber and phenolic compounds. This study examined the effect of peanut shell ground to different sizes (212, 500, and 800 µm) on the physical ...
Ülgen İlknur Konak Alkış +2 more
wiley +1 more source
MetabolitesBackground: This study investigated the hypolipidemic and hepatoprotective effects of refined soybean oil supplemented with an Ocimum basilicum L. extract, characterized by HPLC and found to be rich in caftaric, caffeic, chicoric, and rosmarinic acids ...
Amani Tayebi +10 more
doaj +1 more source
, 2017 The hypolipidemic effect of simvastatin varies greatly among patients. In the current study, we investigated the gut microbial-involved mechanisms underlying the different responses to simvastatin. Male C57BL/6J mice were divided into control (Con), high-
Houkai Li +13 more
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