Synthesis and In Vitro Evaluation of Caffeoylquinic Acid Derivatives as Potential Hypolipidemic Agents [PDF]
Molecules, 2019 A series of novel caffeoylquinic acid derivatives of chlorogenic acid have been designed and synthesized. Biological evaluation indicated that several synthesized derivatives exhibited moderate to good lipid-lowering effects on oleic acid-elicited lipid ...
Yu Tian +7 more
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Changes in LDL-C levels among primary health care patients with hypertension, coronary artery disease, and diabetes during a 36-month follow-up [PDF]
Scandinavian Journal of Primary Health CareBackground and aims Low-density lipoprotein cholesterol (LDL-C) level is one important modifiable risk factor for cardiovascular diseases. This study aimed to describe the characteristics of primary health care patients with hypertension, coronary artery
Petra Valkonen +4 more
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The association between TyG index and cardiovascular mortality is modified by antidiabetic or lipid-lowering agent: a prospective cohort study [PDF]
Cardiovascular DiabetologyBackground The triglyceride-glucose (TyG) index is recognized as an alternative measure of insulin resistance (IR) and has been linked to the risks of cardiovascular disease (CVD) and mortality.
Changchang Fang +10 more
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MODELING OF MICE AS TEST ANIMALS FOR A PRECLINICAL STUDY OF HYPOLIPIDEMIC AGENTS [PDF]
Jurnal Farmasi Sains dan Praktis, 2023 Animal models suitable for preclinical research are necessary for the discovery of hypolipidemic agents. Various publications have presented alternative dyslipidemia animal models, but identifying a feasible and stable method would serve as a solid ...
Setiyo Budi Santoso +2 more
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A Proof-of-Concept for a Hypolipidemic Brown Trout Model
ToxicsThe impacts of hypolipidemic pharmaceuticals on fish lipid metabolism remain unexplored. However, data points to similar effects and mechanisms of action between fish and humans.
Tiago Lourenço +4 more
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Assessing the adherence to and the therapeutic effectiveness of hypolipidemic agents in a population of patients in Brazil: a retrospective cohort study. [PDF]
Pharm Pract (Granada), 2014 Objective: to evaluate the relation between patient adherence and therapeutic effectiveness of hypolipidemic agents in clinical practice. Methods: A retrospective cohort study of 417 patients using hypolipidemic drugs (simvastatin, atorvastatin) between
Cunico C +3 more
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Trixis angustifolia DC. as a potential plant for the co-management of diabetes mellitus and tuberculosis. [PDF]
PLoS ONEDiabetes mellitus and tuberculosis represent two concurrent conditions that have posed significant challenges to global public health. A comprehensive investigation into new strategies for co-managing both conditions is essential, given the possible drug
Anuar Salazar-Gómez +7 more
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Hypolipidemic effect of Silymarin in Dyslipidaemia of Different Etiologies [PDF]
مجلة كلية الطب, 2008 Background: Many drug and non drug approaches are utilized for the treatment of dyslipidemia; flavonoids, the major constituents of silymarin, have been proved to positively modify lipoproteins in experimentally – induced dyslipidemia.
Bahir Abdul Razzaq Mesheimish +4 more
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Nitrogen Monoxide Releasing Nitric Ester Derivatives of Ibuprofen and Naproxen as COX Inhibitors, Anti-Inflammatory and Hypolipidemic Compounds [PDF]
MoleculesNitric esters are among the compounds that can liberate nitrogen monoxide (NO) in the organism. Due to the vasodilatation caused by nitrogen monoxide, NO-donors have been shown to protect endothelial function, acting as vasodilators, promoting efficient ...
Paraskevi Tziona +4 more
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Cocos Nucifera Endocarp Extract Exhibits Anti-diabetic and Antilipidemic Activities in Diabetic Rat Model [PDF]
International Journal of Scientific Research in Dental and Medical Sciences, 2022 Background and aim: The fruits of Cocos nucifera have long been used in traditional medicine as anti-inflammatory, antimicrobial, antiparasitic, anticancer, and cardiotonic.
Farjana Akter +5 more
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