Results 11 to 20 of about 10,875 (185)

Associations between education level, blood-lipid measurements and statin treatment in a Danish primary health care population from 2000 to 2018

Scandinavian Journal of Primary Health Care, 2023
Objective To examine whether education level influences screening, monitoring, and treatment of hypercholesterolemia.Design Epidemiological cohort study.Setting Department of Clinical Biochemistry, Copenhagen University Hospital Hvidovre.Subjects ...
Marius Mølsted Flege, Margit Kriegbaum, Henrik Løvendahl Jørgensen, Bent Struer Lind, Lise Bathum, Christen Lykkegaard Andersen, Anna Elise Engell   +6 more
doaj   +1 more source

Extreme lipoprotein(a) in clinical practice: A cross sectional study

International Journal of Cardiology. Cardiovascular Risk and Prevention, 2023
Introduction: Measurement of lipoprotein(a) [Lp(a)] is recommended once in a lifetime to identify individuals at high risk of atherosclerotic cardiovascular disease (ASCVD).
Barak Zafrir, Amir Aker, Walid Saliba
doaj   +1 more source

PCSK9 Antagonists: Clinical Efficacy and Main Trends in the Development of New Medicines

Безопасность и риск фармакотерапии, 2023
Scientific relevance. Cardiovascular diseases (CVD) are the leading cause of death worldwide. Dyslipidemia, as the pathophysiological basis of atherosclerosis, is the most important cause of CVD.
A. A. Nekipelova, R. N. Alyautdin
doaj   +1 more source

Effect of Early Initiation of Evolocumab on Lipoprotein(a) in Patients with Acute Myocardial Infarction: Sub-Analysis of a Randomized Controlled Trial

Journal of Cardiovascular Development and Disease, 2022
Elevated circulating lipoprotein(a) levels are associated with an increased risk of cardiovascular events. We reported that early initiation of evolocumab, a proprotein convertase subtilisin/kexin type 9 inhibitor, in addition to a statin substantially ...
Tomoaki Okada, Toru Miyoshi, Masayuki Doi, Kazumasa Nosaka, Ryu Tsushima, Satoko Ugawa, Wataru Takagi, Masahiro Sogo, Masahiko Takahashi, Hiroshi Ito   +9 more
doaj   +1 more source

Antioxidant and Hypolipidemic Activities of Cinnamic Acid Derivatives

Molecules, 2023
Oxidative stress and hyperlipidemia are important factors for the initiation and progression of various cell degenerative pathological conditions, including cardiovascular and neurological diseases.
Christina Nouni, Panagiotis Theodosis-Nobelos, Eleni A. Rekka   +2 more
doaj   +1 more source

Inhibition of palmitoyl CoA deacylase by chlorophenoxyisobutyrate and betabenzalbutyrate

Journal of Lipid Research, 1973
Palmitoyl CoA deacylase activity was measured in preparations of rat liver microsomes. Two hypolipidemic agents, chlorophenoxyisobutyrate and betabenzalbutyrate caused inhibition of palmitoyl CoA deacylase in vitro.
Robert G. Lamb, Patsy M. Hill, Harold J. Fallon   +2 more
doaj   +1 more source

Study of prescribing patterns of hypolipidemic agents in a tertiary care teaching hospital in North India

National Journal of Physiology, Pharmacy and Pharmacology, 2017
Background: Lipid-lowering agents are now the cornerstone of treatment used to reduce the risk of coronary events. Since there is wide variation in selection and use of these drugs, drug utilization studies help to evaluate and analyze drug therapy from ...
Seema Gupta, Rajesh Kumar, Dharminder Kumar, Sanjeev Bhat, Dinesh Kumar, Nusrat Kareem Bhat, Surbhi Mahajan   +6 more
doaj   +1 more source

REvisiting Lipids in REtinal Diseases: A Focused Review on Age-related Macular Degeneration and Diabetic Retinopathy

Journal of Lipid and Atherosclerosis, 2020
Dyslipidemia refers to an abnormal amount of lipid in the blood, and the total cholesterol level is defined as the sum of high-density lipoprotein cholesterol, low-density lipoprotein (LDL) cholesterol, and very-LDL cholesterol concentrations.
Su Jin Park, Dong Ho Park
doaj   +1 more source

The Use of Primary Care Electronic Health Records for Research: Lipid Medications and Mortality in Elderly Patients

Pharmacy, 2019
General practice electronic health record (EHR) data have significant potential for clinical research. This study demonstrates the feasibility of utilising longitudinal EHR data analysis to address clinically relevant outcomes and uses the relationship ...
Adam J. Hodgkins, Judy Mullan, Darren J. Mayne, Andrew Bonney   +3 more
doaj   +1 more source

Microwave-Assisted Synthesis, Biological Activity Evaluation, Molecular Docking, and ADMET Studies of Some Novel Pyrrolo [2,3-b] Pyrrole Derivatives

Molecules, 2022
Novel pyrrolo [2,3-b] pyrrole derivatives were synthesized and their hypolipidemic activity was assessed in hyperlipidemic rats. The chemical structures of the new derivatives were confirmed through spectral analysis.
Moumen S. Kamel, Amany Belal, Moustafa O. Aboelez, E. Kh. Shokr, H. Abdel-Ghany, Hany S. Mansour, Ahmed M. Shawky, Mahmoud Abd El Aleem Ali Ali El-Remaily   +7 more
doaj   +1 more source