Results 31 to 40 of about 11,363 (224)

Novel Hypolipidemic Agents: Focus on PCSK9 Inhibitors

, 2013
Proprotein convertase subtilisin/kexin type 9 (PCSK9) was recently discovered as the third gene involved in autosomal dominant familial hypercholesterolemia.
Manolis, Theodora A, Melita, Helen, Manolis, Antonis S   +2 more
core   +1 more source

Indole-Based Fibrates as Potential Hypolipidemic and Antiobesity Agents

, 2016
Hypolipidemic and antiobesity effects of the newly synthesized indole-based fibrates were evaluated in Triton WR-1339 and high fat diet (HFD)-induced hyperlipidemic rats.
Bhanu Shankar Singh (2100523), Koneni V. Sashidhara (1338594), Gitika Bhatia (2100517), Manoj Kumar (205700), Ravi Sonkar (2100526), A. K. Khanna (2100520)   +5 more
core   +1 more source

Comparative analysis of the use of lipid modifying agents in the Republic of Serbia and Nordic countries in the period 2015-2017 [PDF]

Hospital Pharmacology, 2020
Introduction: Cardiovascular diseases are the leading cause of death both in Serbia and in the rest of the world. It has been shown that as many as 80% of them are preventable.
Martić Nikola B., Zečević Dragan D., Đurđević Milena V., Milijašević Dragana S., Tomić Nataša Z., Lalić-Popović Mladena N., Todorović Nemanja B., Medin Danilo V., Mićanović Branimir B., Milijašević Boris Ž.   +9 more
doaj  

Investigation of the Characteristics of Hypolipidemic Drug Use at Hospitals in Okinawa [PDF]

, 2004
We investigated the characteristics of hypolipidemic drug use at hospitals in Okinawa. We constructed a drug information database for prescriptions issued by 5 hospitals with over 300 beds in Okinawa (Okinawa Hokubu Hospital, Okinawa Chubu Hospital ...
橋本, フミ惠, 翁長, 真一郎, 芳原, 準男, 林, 秀徳, 上原, 正徳   +4 more
core   +1 more source

Design, synthesis, and docking of highly hypolipidemic agents: Schizosaccharomyces pombe as a new model for evaluating a-asarone-based HMG-CoA reductase inhibitors [PDF]

, 2013
Design, synthesis, and docking of highly hypolipidemic agents: Schizosaccharomyces pombe as a new model for evaluating a-asarone-based HMG-CoA reductase ...
Cruz López, María del Carmen
core   +1 more source

Bempedoic acid and its role in contemporary management of hyperlipidemia in atherosclerosis

Annals of Medicine, 2022
Atherosclerotic heart disease is the leading cause of mortality and morbidity in the USA. Low density lipoprotein (LDL) has been the target for many hypolipidemic agents to modify atherosclerotic risk.
Ramyashree Tummala, Manasvi Gupta, Arvind Reddy Devanabanda, Dhrubajyoti Bandyopadhyay, Wilbert S. Aronow, Kausik K. Ray, Mamas Mamas, Raktim K. Ghosh   +7 more
doaj   +1 more source

Preparation, Component Identification, and Antioxidant Activity of Anthocyanins From Punica granatum “Tunisia”

AgriFood: Journal of Agricultural Products for Food, EarlyView.
The preparation for Tunisian pomegranate anthocyanin extract. The molecular mechanisms underlying the antioxidant effects of these compounds were investigated using network pharmacology and molecular docking. Antioxidant activity was evaluated through DPPH, ABTS, and FRAP assays, whereas the effects on oxidative stress and inflammation were examined in
Jing Zhang, Xu‐han Yang, Meng‐qi Zhang, Xu Guo, Ning‐yang Li, Fang‐yu Long, Chao Liu   +6 more
wiley   +1 more source

PPAR alpha structure-function relationships derived from species-specific differences in responsiveness to hypolipidemic agents.

, 1997
The nuclear receptor PPAR alpha is a key regulatory transcription factor in lipid homeostasis, some liver detoxification processes and the control of inflammation.
Wahli, W., Keller, H., Devchand, P.R., Perroud, M.   +3 more
core   +1 more source

Lactucin & Lactucopicrin ameliorates FFA-induced steatosis in HepG2 cells via modulating lipid metabolism

Journal of Pharmacological Sciences, 2022
Non-alcoholic fatty liver disease (NAFLD) is one of the most common chronic liver diseases, and there are no effective drugs available so far. Lactucin and Lactucopicrin belong to sesquiterpene lactones and are extracted from Cichorium glandulosum Boiss.
Yilizere Aibaidula, Mutalifu Aimaiti, Huiwen Tan, Bingting Chen, Jian Yang, Xiaoli Ma   +5 more
doaj   +1 more source

Potential of Bee Pollen as a Nutraceutical And/Or Functional Ingredient for Metabolic Syndrome Management: In Vitro Antioxidant, Anti‐Inflammatory, and Digestive Enzyme Inhibitory Activities

Food Chemistry International, EarlyView.
Bee pollen samples from China and Spain exhibited in vitro antioxidant, anti‐inflammatory, and digestive enzyme inhibitory activities due to their composition, suggesting their potential as a nutraceutical or functional ingredient to help counteract oxidative stress, chronic inflammation, and metabolic disorders.
Adriana Maite Fernández‐Fernández, Victoria Olt, Jessica Báez, Marcelo Miraballes, Melissa Romero, Cecilia Dauber, Ignacio Vieitez, Estela Santos, Adriana Gámbaro, Alejandra Medrano   +9 more
wiley   +1 more source