Results 21 to 30 of about 11,363 (224)

Effect of Early Initiation of Evolocumab on Lipoprotein(a) in Patients with Acute Myocardial Infarction: Sub-Analysis of a Randomized Controlled Trial

Journal of Cardiovascular Development and Disease, 2022
Elevated circulating lipoprotein(a) levels are associated with an increased risk of cardiovascular events. We reported that early initiation of evolocumab, a proprotein convertase subtilisin/kexin type 9 inhibitor, in addition to a statin substantially ...
Tomoaki Okada, Toru Miyoshi, Masayuki Doi, Kazumasa Nosaka, Ryu Tsushima, Satoko Ugawa, Wataru Takagi, Masahiro Sogo, Masahiko Takahashi, Hiroshi Ito   +9 more
doaj   +1 more source

REvisiting Lipids in REtinal Diseases: A Focused Review on Age-related Macular Degeneration and Diabetic Retinopathy

Journal of Lipid and Atherosclerosis, 2020
Dyslipidemia refers to an abnormal amount of lipid in the blood, and the total cholesterol level is defined as the sum of high-density lipoprotein cholesterol, low-density lipoprotein (LDL) cholesterol, and very-LDL cholesterol concentrations.
Su Jin Park, Dong Ho Park
doaj   +1 more source

Inhibition of palmitoyl CoA deacylase by chlorophenoxyisobutyrate and betabenzalbutyrate

Journal of Lipid Research, 1973
Palmitoyl CoA deacylase activity was measured in preparations of rat liver microsomes. Two hypolipidemic agents, chlorophenoxyisobutyrate and betabenzalbutyrate caused inhibition of palmitoyl CoA deacylase in vitro.
Robert G. Lamb, Patsy M. Hill, Harold J. Fallon   +2 more
doaj   +1 more source

Study of prescribing patterns of hypolipidemic agents in a tertiary care teaching hospital in North India

National Journal of Physiology, Pharmacy and Pharmacology, 2017
Background: Lipid-lowering agents are now the cornerstone of treatment used to reduce the risk of coronary events. Since there is wide variation in selection and use of these drugs, drug utilization studies help to evaluate and analyze drug therapy from ...
Seema Gupta, Rajesh Kumar, Dharminder Kumar, Sanjeev Bhat, Dinesh Kumar, Nusrat Kareem Bhat, Surbhi Mahajan   +6 more
doaj   +1 more source

Microwave-Assisted Synthesis, Biological Activity Evaluation, Molecular Docking, and ADMET Studies of Some Novel Pyrrolo [2,3-b] Pyrrole Derivatives

Molecules, 2022
Novel pyrrolo [2,3-b] pyrrole derivatives were synthesized and their hypolipidemic activity was assessed in hyperlipidemic rats. The chemical structures of the new derivatives were confirmed through spectral analysis.
Moumen S. Kamel, Amany Belal, Moustafa O. Aboelez, E. Kh. Shokr, H. Abdel-Ghany, Hany S. Mansour, Ahmed M. Shawky, Mahmoud Abd El Aleem Ali Ali El-Remaily   +7 more
doaj   +1 more source

The Use of Primary Care Electronic Health Records for Research: Lipid Medications and Mortality in Elderly Patients

Pharmacy, 2019
General practice electronic health record (EHR) data have significant potential for clinical research. This study demonstrates the feasibility of utilising longitudinal EHR data analysis to address clinically relevant outcomes and uses the relationship ...
Adam J. Hodgkins, Judy Mullan, Darren J. Mayne, Andrew Bonney   +3 more
doaj   +1 more source

HOW DO VITAMIN AND PLANT SEEDS WORK AS HYPOLIPIDEMIC AGENTS ? [PDF]

, 2017
Objectives: Cardiovascular diseases are leading cause of death in western and eastern countries of the world. Hyperlipidemia is one of the strong risk fractions for heart diseases.
Niaz, Khalid, Murad, Shah, Ali, Azmat, Aslam, Hina   +3 more
core   +1 more source

The ansamycins: hypolipidemic agents stimulating cholesterol removal by nonclassical mechanisms.

Journal of Lipid Research, 1994
The ansamycins CGP 43371 and CGS 24565 are derivatives of the antibiotic rifamycin that reduce plasma cholesterol levels in both primate and nonprimate species.
J C Gibson, W H Lee, J R Piccolo
doaj   +1 more source

Synthesis and Biological Evaluation of Orally Active Hypolipidemic Agents

, 2016
A series of novel fenofibric acid ester prodrugs 1c–1h were synthesized and evaluated with the aim of obtaining potent hypolipidemic agents. Prodrugs 1c and 1d exhibited potent hypochlolesterolemic activity, lowering the mice plasma triglyceride level up
Jeyamurugan Mookkan (2174504), Gajendra Singh (2174498), Babasaheb P. Bandgar (808350), Pranesha Shetty (2174502), Rajendra J. Sarangdhar (2174496), Fruthous Khan (2174500)   +5 more
core   +1 more source

Study on the influence of 7-β-hydroxy-γ-aryloxypropylxanthinyl-8-thioalkanic acid derivatives on the lipid metabolism in experiment

Zaporožskij Medicinskij Žurnal, 2021
Statin side effects are not a rare occurrence, in particular dyspeptic disorders, insomnia, headache, skin erythema, rash are often noted. All of this determines scientists to find new effective and low-toxic hypolipidemic agents.
I. M. Bilai, M. I. Romanenko, D. H. Ivanchenko   +2 more
doaj   +1 more source