Results 51 to 60 of about 10,875 (185)

Anticancer and Cardioprotective Properties of Medicinal Mushrooms: Current Evidence and Future Prospects

New Zealand Journal of Botany, Volume 64, Issue 3, September 2026.
Introduction: Cardiotoxicity is an undesirable side effect of chemotherapy that limits the effectiveness of cancer treatment. Almost all cardiotoxic agents cause cardiovascular complications, leading to oxidative stress and other pathological conditions.
Susanna Badalyan, Sylvie Rapior, Anush Barkhudaryan   +2 more
wiley   +1 more source

Effect of VIVO(dipic-Cl)(H2O)2 on Lipid Metabolism Disorders in the Liver of STZ-Induced Diabetic Rats

Journal of Diabetes Research, 2013
Vanadium complexes are potent antidiabetic agents for therapeutical treatment of diabetes. In the present study, we investigated the hypolipidemic effect of VIVO(dipic-Cl)(H2O)2 (V4dipic-Cl) in liver of streptozotocin- (STZ-)-induced diabetic rats.
Fang Liu, Mingxia Xie, Deliang Chen, Jian Li, Wenjun Ding   +4 more
doaj   +1 more source

PCSK9 Inhibitors: Clinical Relevance, Molecular Mechanisms, and Safety in Clinical Practice

Arquivos Brasileiros de Cardiologia, 2019
Coronary artery disease (CAD) is one of the leading causes of mortality. High circulating levels of low-density lipoprotein (LDL) in the blood are associated with cardiovascular mortality, whether through an etiological role or through its association ...
Filipe Ferrari, Ricardo Stein, Marcelo Trotte Motta, Emilio Hideyuki Moriguchi   +3 more
doaj   +1 more source

Angiopoietin‐like protein 3 complete and partial deficiency markedly accelerates apolipoprotein B48 and B100 metabolism in triglyceride‐rich lipoproteins in humans

Journal of Internal Medicine, Volume 300, Issue 3, Page 312-328, September 2026.
Abstract Background Angiopoietin‐like protein 3 (ANGPTL3) is a key circulating regulator of triglyceride metabolism and a promising pharmacological target. The physiological consequences of profound ANGPTL3 deficiency can be explored in individuals with inherited loss‐of‐function (LOF) variants, who show reduced lifetime risk of atherosclerotic ...
Marcello Arca, Elias Björnson, Laura D'Erasmo, Alessia Di Costanzo, Simone Bini, Ilenia Minicocci, Daniele Tramontano, Stella Covino, Giuseppe Ciarlo, Manuela Lombardi, Sanni Söderlund, Niina Matikainen, Linda Andersson, Martin Adiels, Marja‐Riitta Taskinen, Chris J. Packard, Jan Borén   +16 more
wiley   +1 more source

Relationship between serum lipids and the risk of hemorrhagic stroke: a meta-analysis of 50 million participants from prospective cohort studies

Lipids in Health and Disease
Background While prior meta-analyses have demonstrated the benefits of lipid-lowering agents for atherosclerotic cardiovascular disease prevention in high-risk populations with definite risk, the applicability of these findings to global community-based ...
Xuefan Yao, Houlin Lai, Kehui Ma, Benke Zhao, Aini He, Wei Sun, Yuan Wang, Haiqing Song   +7 more
doaj   +1 more source

Probiotic fermented goat milk incorporated with blackberry (Rubus sp.): A novel functional food product

Journal of the Science of Food and Agriculture, Volume 106, Issue 11, Page 6640-6647, 30 August 2026.
Abstract BACKGROUND This study created functional fermented goat milk by adding blackberry pulp and probiotics (Lactobacillus acidophilus LA‐5 and Bifidobacterium animalis subsp. lactis Bb‐12). The preparation involved two variations of fermented goat milk with blackberry (Rubus sp.), distinguished by the absence (fermented goat milk, FGM) or inclusion
Bibiana Bittencourt Bicca, Khadija Bezerra Massaut, Elisa dos Santos Pereira, Márcia Vizzotto Foster, Laura Martins Fonseca, Ângela Maria Fiorentini, Graciela Volz Lopes   +6 more
wiley   +1 more source

Antihyperglycemic and Hypolipidemic Activities of Flavonoids Isolated from Smilax Dominguensis Mediated by Peroxisome Proliferator-Activated Receptors

Pharmaceuticals
Background/objetives: Mexican people use Smilax dominguensis as a traditional medicine for diabetes control. Some reports have shown an anti-hyperglycemic effect in animal models.
Erandi Ortiz-Barragán, Samuel Estrada-Soto, Abraham Giacoman-Martínez, Francisco J. Alarcón-Aguilar, Ángeles Fortis-Barrera, Hugo Marquina-Rodríguez, Emmanuel Gaona-Tovar, Roberto Lazzarini-Lechuga, Alfredo Suárez-Alonso, Julio César Almanza-Pérez   +9 more
doaj   +1 more source

Targeting ANGPTL3 and IL‐33/ST2 Ameliorates Diabetic Kidney Disease by Reducing Lipotoxicity, Alleviating Inflammation and Inhibiting Fibrosis

Advanced Science, Volume 13, Issue 45, 13 August 2026.
Dual targeting of ANGPTL3 and IL‐33/ST2 attenuates diabetic kidney disease by reprogramming lipid–inflammatory crosstalk. This strategy reduces renal lipotoxicity, suppresses inflammatory activation, and limits fibrotic remodeling, thereby preserving kidney structure and function and highlighting a mechanism‐guided therapeutic approach for metabolic ...
Zhuojin Li, Zhonglian Cao, Rongrui Zhou, Xu Cheng, Xiaozhi Hu, Shuwen Xu, Zihan Dou, Ling Du, Dianwen Ju   +8 more
wiley   +1 more source

Cordyceps militaris Ethanol Extract Alleviates Hyperglycemia in Type 2 Diabetic Mice in Association With Gut Microbiota Modification

eFood, Volume 7, Issue 4, August 2026.
Cordyceps militaris ethanol extract (CME) shows potential for ameliorating glucose and lipid metabolism in T2DM mice. The improvements are correlated with the regulation of gut microbiota and increased short‐chain fatty acid levels, offering a novel perspective for future diabetes interventions.
Huanhuan Wen, Wenke Hu, Xinru Xu, Na Wu, Huangcong Ding, Haonan Wang, Xiaoyu Gao, Ligen Chen, Chao Zhao, Rong Shao, Wei Xu   +10 more
wiley   +1 more source

Hypolipidemic therapy in patients with non-alcoholic fatty liver disease

КардиоСоматика, 2010
Dyslipidemia is currently accepted to be one of the major risk factor for cardiovascular diseases and atherosclerosis. There is no question that the liver plays an important role in the development of atherogenic dyslipidemia and it is simultaneously a ...
L. B Lazebnik, L. A Zvenigorodskaya, N. G Samsonova, E. A Cherkasova, N. V Melnikova   +4 more
doaj