Results 51 to 60 of about 1,515,353 (171)

Linking Cardiovascular Disease and Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD): The Role of Cardiometabolic Drugs in MASLD Treatment

Biomolecules
The link between cardiovascular disease (CVD) and metabolic dysfunction-associated steatotic liver disease (MASLD) is well-established at both the epidemiological and pathophysiological levels.
Marios Zisis, Maria Eleni Chondrogianni, Theodoros Androutsakos, Ilias Rantos, Evangelos Oikonomou, Antonios Chatzigeorgiou, Eva Kassi   +6 more
doaj   +1 more source

Lipid-lowering drug prescriptions in a group of Colombian patients

Biomédica: revista del Instituto Nacional de Salud, 2019
Introduction. Lipid-lowering drugs, especially statins, have shown great relevance in preventing and treating cardiovascular diseases. Objective. To determine the prescription patterns of lipid-lowering drugs and the variables associated with their use ...
Andres Gaviria-Mendoza, Manuel E. Machado-Duque, Jorge E. Machado-Alba   +2 more
doaj   +1 more source

Mode‐of‐Action and Human Relevance Assessment for Diisononyl Phthalate‐Induced Liver Tumors in Rodents

Journal of Applied Toxicology, EarlyView.
ABSTRACT Diisononyl phthalate (DINP) is a high molecular weight phthalate and high production volume chemical. DINP's carcinogenic potential has been investigated in four rodent bioassays, with liver tumors observed in three of the studies. Authoritative assessments have hypothesized that DINP acts through the peroxisome proliferator‐activated receptor
Amanda N. Buerger, Melissa M. Heintz, Laurie C. Haws, Chad M. Thompson   +3 more
wiley   +1 more source

Study of drug utilization, morbidity pattern and cost of hypolipidemic agents in a tertiary care hospital [PDF]

, 2017
Background: Data on the extent of use and costs of lipid-lowering agents are not widely available. Our aim was to study the drug utilization and morbidity pattern, cost of different hypolipidemic drugs along with the risk assessment for coronary heart ...
Joshi, Harsh M., Patel, Varsha J., Khandhedia, Chintan, Patel, Kamlesh P., Shah, Harsh, Shah, Kartik N.   +5 more
core  

Effects of Hypoglycemic and Hypolipidemic Drugs on Intestinal Microbiocenosis in Cardiometabolic Disorders

Медицина и биотехнологии
Introduction. Intestinal microbiocenosis plays a key role in maintaining the body’s homeostasis, but its composition can be disrupted by various factors, including medications.
Andrey A. Kotlyarov, Tatyana V. Ulanova, Elizaveta D. Aristova, Nikita S. Fomenko, Yulia A. Kotlyarova, Svetlana G. Kolesnikova   +5 more
doaj   +1 more source

Bempedoic acid and its role in contemporary management of hyperlipidemia in atherosclerosis

Annals of Medicine, 2022
Atherosclerotic heart disease is the leading cause of mortality and morbidity in the USA. Low density lipoprotein (LDL) has been the target for many hypolipidemic agents to modify atherosclerotic risk.
Ramyashree Tummala, Manasvi Gupta, Arvind Reddy Devanabanda, Dhrubajyoti Bandyopadhyay, Wilbert S. Aronow, Kausik K. Ray, Mamas Mamas, Raktim K. Ghosh   +7 more
doaj   +1 more source

Gymnema sylvestre: Bioactive constituents, health benefits, and emerging applications in nutraceuticals and functional foods

JSFA reports, EarlyView.
Abstract Gymnema sylvestre (Retz.) R.Br. ex‐Schult., commonly known as “gurmar” or “sugar destroyer,” belongs to the Apocynaceae family and is traditionally used in Ayurveda for diabetes management. This review synthesizes ethnomedicinal evidence with contemporary pharmacological studies, to evaluate the therapeutic properties and mechanistic actions ...
Faiza Saeed, Muhammad Tauseef Sultan, Hassan Raza, Ahmad Mujtaba Noman, Nimra Haroon, Entessar Mohammad Al Jbawi   +5 more
wiley   +1 more source

Comparative analysis of the use of lipid modifying agents in the Republic of Serbia and Nordic countries in the period 2015-2017 [PDF]

Hospital Pharmacology, 2020
Introduction: Cardiovascular diseases are the leading cause of death both in Serbia and in the rest of the world. It has been shown that as many as 80% of them are preventable.
Martić Nikola B., Zečević Dragan D., Đurđević Milena V., Milijašević Dragana S., Tomić Nataša Z., Lalić-Popović Mladena N., Todorović Nemanja B., Medin Danilo V., Mićanović Branimir B., Milijašević Boris Ž.   +9 more
doaj  

Hypolipidemic Effects of β-Glucans, Mannans, and Fucoidans: Mechanism of Action and Their Prospects for Clinical Application

Molecules, 2020
The search for lipid-lowering drugs is important for clinical medicine. This review summarizes our research findings regarding the hypolipidemic activity of polysaccharides.
Tatiana A. Korolenko, Nataliya P. Bgatova, Marina V. Ovsyukova, Alexandra Shintyapina, Vaclav Vetvicka   +4 more
doaj   +1 more source

Lactucin & Lactucopicrin ameliorates FFA-induced steatosis in HepG2 cells via modulating lipid metabolism

Journal of Pharmacological Sciences, 2022
Non-alcoholic fatty liver disease (NAFLD) is one of the most common chronic liver diseases, and there are no effective drugs available so far. Lactucin and Lactucopicrin belong to sesquiterpene lactones and are extracted from Cichorium glandulosum Boiss.
Yilizere Aibaidula, Mutalifu Aimaiti, Huiwen Tan, Bingting Chen, Jian Yang, Xiaoli Ma   +5 more
doaj   +1 more source