Results 71 to 80 of about 1,515,353 (171)
Objective Dyslipidemia is a major modifiable risk factor for cardiovascular disease (CVD). We investigated temporal trends in CVD incidence and lipid-lowering therapy in individuals with dyslipidemia.
Osung Kwon +6 more
doaj +1 more source
Traditional Uses, Phytochemistry, and Multi‐Target Pharmacological Activities of Senna alexandrina
Senna alexandrina is a medicinally important plant with documented use across Traditional Chinese, Islamic, Ayurvedic, and Unani medicine systems. Phytochemical investigations have yielded 219 characterized compounds, predominantly anthraquinones, flavonoids, and polysaccharides, distributed across leaves, pods, and aerial parts.
Diana Afrina Rella +2 more
wiley +1 more source
Effects of fenofibrate on lipid parameters in obese rhesus monkeys
Fenofibrate is a member of the fibrate class of hypolipidemic agents used clinically to treat hypertriglyceridemia and mixed hyperlipidemia. The fibrates were developed primarily on the basis of their cholesterol and triglyceride lowering in rodents ...
Deborah A. Winegar +12 more
doaj +1 more source
Polyphenol‐rich plant extracts provide natural immunomodulatory protection for oral health through complementary antioxidant, antibacterial, and anti‐inflammatory actions. Their potential to reduce harmful microbial activity and inflammation highlights the promise of dietary polyphenols as a natural strategy for maintaining oral health and preventing ...
Deepa Subramanian +3 more
wiley +1 more source
Bioactive peptides in cancer and inflammation: Mechanisms, model systems and clinical translation
Bioactive peptides (BAPs) derived from host, marine, insect, plant and synthetic sources share cationic, amphipathic structures adopting α‐helical, β‐sheet or cyclic conformations. These features underlie anti‐cancer effects, including membrane disruption, apoptosis and cell‐cycle arrest, anti‐metastatic activity, reduced invasion and migration, and ...
Najwa Doha +4 more
wiley +1 more source
This graphical abstract illustrates the complete translational pipeline of Terminalia arjuna in modern phytomedicine and functional food development. It is rich in key bioactive compounds like arjunolic acid, arjungenin, flavonoids, and tannins which serve as the foundation for the plant's versatile medicinal uses and offers broad therapeutic benefits ...
Ishani Banerjee +5 more
wiley +1 more source
Synthesis, molecular docking and evaluation of hypolipidemic activities of novel benzophenonecarboxamide derivatives [PDF]
587-593Fibrates are well known hypolipidemic agents and act by activating Peroxisome Proliferator-Activated Receptors (PPAR); this family of receptors is the main regulator for fatty acid metabolism.
Al-Jaidi, Bilal +6 more
core
The synthesis of isoxazole-based derivatives utilizing Baylis-Hillman chemistry and results of their preliminary bioevaluation as hypolipidemic agents in triton model are ...
Bhaduri, A. P. +5 more
core +1 more source
Evaluation of the Solubility Profiles of Hypolipidemic Drugs [PDF]
Hypolipidemic agents represent an important class of drugs used in the treatment of hyperlipoproteinemia. Statins are reversible, competitive inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A reductase, ezetimibe selectively inhibits intestinal and ...
Nemanja Turković +4 more
doaj +1 more source
Roasted and non‐roasted Argania spinosa seed oils were evaluated in streptozotocin‐induced diabetic rats. Biochemical and histopathological analyses assessed glucose regulation, lipid metabolism, oxidative stress, liver enzymes, glycogen content, and tissue architecture.
Nour Elhouda Daoudi +9 more
wiley +1 more source

