Results 191 to 200 of about 10,287 (203)
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Terephthalic Acid in Sprague‐Dawley Rats as a Hypolipidemic Agent
Archiv der Pharmazie, 1993AbstractTerephthalic acid at 20 mg/kg/day in lowered serum cholesterol and triglyceride levels in rats. The cholesterol content was lowered in the lipoprotein fractions. The effects of the agents on de novo lipid synthesis showed that similar enzymes were affected in rat liver and small intestinal mucosa cells as when compared to in vitro tissue ...
Iris H. Hall +4 more
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Chapter 17. Progress in Atherosclerosis Therapy: Hypolipidemic Agents
1983Publisher Summary The importance of the lipoprotein transport system to the regulation of plasma lipid levels in human is firmly established. This system is responsible for delivering triglycerides (TG) primarily to adipose and muscle tissues and for continuously shuttling cholesterol between intestine, liver, and extrahepatic tissues.
C. Stanley Rooney, John D. Prugh
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Hypolipidemic agent probucol (mechanisms of action, hypolipidemic effects, and clinical studies). Review [PDF]
Pharmaceutical Chemistry Journal, 1995 V. P. Lupanov +2 more
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1 The Discovery and Development of Atorvastatin, A Potent Novel Hypolipidemic Agent
2002The search for potent and efficacious inhibitors of the enzyme HMG-CoA reductase (HMGRI) was the focus of considerable research in the 1980s. Building on the discovery of the fungal metabolite-derived inhibitors, mevastatin, lovastatin, pravastatin and simvastatin, a number of totally synthetic inhibitors were discovered and developed.
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Criteria for use of hypolipidemic agents in adults
American Journal of Health-System Pharmacy, 1994E Morales +4 more
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Appraisal of clofibrate as a hypolipidemic agent
American Heart Journal, 1968openaire +3 more sources