Results 61 to 70 of about 36,662 (245)

Disturbances of sodium in critically ill adult neurologic patients: A clinical review [PDF]

open access: yes, 2006
Disorders of sodium and water balance are common in critically ill adult neurologic patients. Normal aspects of sodium and water regulation are reviewed. The etiology of possible causes of sodium disturbance is discussed in both the general inpatient and
Crocker, M   +3 more
core  

Prevalence, Risk Factors, and Short-term Consequences of Traumatic Brain Injury-associated Hyponatremia [PDF]

open access: yes, 2015
Hyponatremia, a common electrolyte disorder associated with traumatic brain injuries (TBIs), has high mortality and morbidity rates. The aim of this study was to identify the risk factors for hyponatremia associated with TBI.
Ichiba, Shingo   +4 more
core   +1 more source

Effect of Cytochrome P450 3A Inhibition and Induction by Itraconazole and Rifampin on Tazemetostat Pharmacokinetics in Patients With Advanced Malignancies

open access: yesClinical Pharmacology in Drug Development, EarlyView.
Abstract This study (NCT04537715) investigated itraconazole (strong cytochrome P450 [CYP] 3A inhibitor) and rifampin (strong CYP3A inducer) on tazemetostat pharmacokinetics. In Part 1, patients received tazemetostat 400 mg orally on Days 1, 15, and 36, and 400 mg twice daily on Days 3‐14 and Days 21‐35.
Yingxue Chen   +6 more
wiley   +1 more source

Postoperative delirium after major orthopedic surgery. [PDF]

open access: yes, 2020
BACKGROUND: Postoperative delirium (POD) is one of the most common complications in older adult patients undergoing elective surgery. Few studies have compared, within the same institution, the type of surgery, risk factors and type of anesthesia and ...
Magid, Steven K.   +3 more
core   +1 more source

Cardiac remodelling in the era of the recommended four pillars heart failure medical therapy

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1029-1044, April 2025.
Abstract Cardiac remodelling is a key determinant of worse cardiovascular outcome in patients with heart failure (HF) and reduced ejection fraction (HFrEF). It affects both the left ventricle (LV) structure and function as well as the left atrium (LA) and the right ventricle (RV).
Giada Colombo   +7 more
wiley   +1 more source

Hyponatremia in Community Acquired Pneumonia in a Tertiary Care Hospital - An Observational Cross-Sectional Study

open access: yesJK Science, 2021
Background: Community-acquired pneumonia (CAP) is one of the most common infectious diseases and is an important cause of mortality and morbidity worldwide. Studies have shown hyponatremia to be a common electrolyte abnormality in pneumonia. The current
Mumina Ramzan   +2 more
doaj  

Targeting the vasopressin type-2 receptor for renal cell carcinoma therapy. [PDF]

open access: yes, 2020
Arginine vasopressin (AVP) and its type-2 receptor (V2R) play an essential role in the regulation of salt and water homeostasis by the kidneys. V2R activation also stimulates proliferation of renal cell carcinoma (RCC) cell lines in vitro.
Calvet, James P   +10 more
core  

Hyponatremia during hospitalization and in-hospital mortality in patients hospitalized from heart failure [PDF]

open access: yes, 2015
BackgroundTo date, the majority of studies on hyponatremia focussed on hyponatremia at admission, and came from developed countries. This study aimed to identify the prevalence of hyponatremia during hospitalization in patients hospitalized for HF and ...
Ball, Patrick A.   +2 more
core   +1 more source

Insights into clinical practice: A national survey on fluid intake management in heart failure

open access: yesESC Heart Failure, EarlyView.
There are differences in clinical practice regarding fluid intake management, which may lead to patients with heart failure receiving different and incohesive recommendations. Therefore, there is a need for unified and nationally accepted guidelines in Sweden regarding management on fluid intake. Abstract Aims Due to insufficient evidence and a lack of
Linn Höög   +3 more
wiley   +1 more source

Congestive heart failure in rats is associated with increased expression and targeting of aquaporin-2 water channel in collecting duct [PDF]

open access: yes, 1997
We tested whether severe congestive heart failure (CHF), a condition associated with excess free-water retention, is accompanied by altered regulation of the vasopressin-regulated water channel, aquaporin-2 (AQP2), in the renal collecting duct.
Andersen, D.   +8 more
core   +2 more sources

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