Results 31 to 40 of about 6,701 (243)
Development of Bone Targeting Drugs. [PDF]
, 2017 The skeletal system, comprising bones, ligaments, cartilage and their connective tissues, is critical for the structure and support of the body. Diseases that affect the skeletal system can be difficult to treat, mainly because of the avascular cartilage
Alméciga-Díaz, Carlos J. +6 more
core +2 more sources
Effect of asfotase alfa in the treatment of hypophosphatasia- A systematic review
Journal of Pharmacy and Bioallied Sciences, 2023 Hypophosphatasia (HPP) is a life-threatening disease that occurs due to the mutation of the TNSALP (Tissue nonspecific isoenzyme of alkaline phosphatase) encoding gene. There is no approved treatment for Hypophosphatasia.
N Jaswanthi +7 more
doaj +1 more source
Hypophosphatasia in the Newborn [PDF]
Archives of Disease in Childhood, 1963 Archives of Disease in ...
Lapatsanis, P. D., Todd, R. M.
openaire +4 more sources
Monitoring guidance for patients with hypophosphatasia treated with asfotase alfa. [PDF]
, 2017 Hypophosphatasia (HPP) is a rare, inherited, systemic, metabolic disorder caused by autosomal recessive mutations or a single dominant-negative mutation in the gene encoding tissue-nonspecific alkaline phosphatase (TNSALP). The disease is associated with
Agnès Linglart +98 more
core +1 more source
Prosthetic Rehabilitation of Hypophosphatasia with Precision Attachment Retained Unconventional Partial Denture: A Case Report [PDF]
Journal of Clinical and Diagnostic Research, 2014 Deficiency of the alkaline phosphatase isoenzyme can lead to a rare hereditary disorder called Hypophosphatasia. It is characterized by defective mineralization of the skeletal and dental structures of the body.
GAYATRI SHEENA SUVARNA +3 more
doaj +1 more source
Archives of Endocrinology and Metabolism, 2021 Objectives: Alkaline phosphatase (ALP) is the main laboratory marker of hypophosphatasia (HPP), a rare disease unknown to most physicians. The prevalence of HPP has been widely discussed in the literature due to the diverse phenotypes of HPP. The purpose
Lucio Henrique Rocha Vieira +4 more
doaj +1 more source
Infantile Hypophosphatasia: Clinical Case
Вопросы современной педиатрии, 2020 Background. Hypophosphatasia is rare hereditary disease caused by deficiency of the tissue-nonspecific alkaline phosphatase isozyme. It manifests with bone and teeth mineralisation defects, electrolyte imbalance, respiratory disorders, convulsive ...
Tatyana V. Gabrusskaya +3 more
doaj +1 more source
Short stature with low serum alkaline phosphatase activity: a case report of hypophosphatasia [PDF]
Annals of Pediatric Endocrinology & Metabolism, 2023 Hypophosphatasia (HPP) is a rare condition characterized by abnormal bone mineralization. The manifestations of HPP vary from no symptoms to intrauterine fetal death; short stature is another indication of HPP.
Donghyun Lee +3 more
doaj +1 more source
Current concepts in odontohypophosphatasia form of hypophosphatasia and report of two cases [PDF]
, 2016 published_or_final_versio
Qiao, W +4 more
core +1 more source
Hypophosphatasia in Taiwan: Report of Two Cases
Kaohsiung Journal of Medical Sciences, 2005 Hypophosphatasia is a rare inherited metabolic disease characterized by rickets with reduced plasma and tissue alkaline phosphatase activity. It may be present in infancy, childhood, or adulthood.
Yen-Yin Chou +2 more
doaj +1 more source