Results 51 to 60 of about 2,414 (178)

pH‐Shift‐Prepared Chlorella pyrenoidosa Protein/Peptide–Calcium Complexes Improve Skeletal Health by Enhanced Intestinal Calcium Utilization in Calcium‐Deficient Rats

Food Frontiers, Volume 7, Issue 3, May 2026.
ABSTRACT Calcium carbonate supplements often exhibit limited solubility and gastrointestinal precipitation, restricting calcium availability. To address this limitation, an enzyme‐free pH‐shift strategy was applied to prepare Chlorella pyrenoidosa protein (CPP)/peptide–calcium complexes (pH–Ca) and to evaluate their effects on calcium utilization in ...
Yan Yang, Shenwan Wang, Qimeng Zhou, Ye Qi, Bin Zhou, Jing Li, Tao Hou, Bin Li, Hongshan Liang   +8 more
wiley   +1 more source

Familial Hypomagnesemia with Hypercalciuria and Nephrocalcinosis Due to CLDN16 Gene Mutations: Novel Findings in Two Cases with Diverse Clinical Features

, 2021
Biallelic loss of function mutations in the CLDN16 gene cause familial hypomagnesemia with hypercalciuria and nephrocalcinosis (FHHNC), and chronic kidney disease. Here we report two cases of FHHNC with diverse clinical presentations and hypercalcemia in
ALAVANDA, CEREN, KIRKGÖZ, TARIK, ARMAN, AHMET, BEREKET, ABDULLAH, ELTAN, MEHMET, DEMİRCİOĞLU, SERAP, GÜRAN, TÜLAY, GÖKCE, İBRAHİM   +7 more
core   +1 more source

Mineral‐targeted alkaline phosphatase improves bone graft‐mediated alveolar bone defect healing in mice

Journal of Periodontology, Volume 97, Issue 5, Page 1071-1085, May 2026.
Abstract Background Alveolar bone loss challenges tooth retention and implant placement. Freeze‐dried bone allograft (FDBA) is widely used for alveolar ridge preservation but has limitations in resorption rate and healing time. In this proof‐of‐concept study, we tested whether pro‐mineralization enzyme, tissue‐nonspecific alkaline phosphatase (TNAP ...
Kedith Sawangsri, Aonjittra Phanrungsuwan, Binnaz Leblebicioglu, José Luis Millán, Brian L. Foster   +4 more
wiley   +1 more source

Carrier screening in the reproductive setting—Are there medical implications for the heterozygote?—A guide for clinicians

Pregnancy, Volume 2, Issue 3, May 2026.
Abstract Carrier screening for genetic conditions performed preconception or during pregnancy allows identification of fetal risk for inherited autosomal recessive and X‐linked conditions. The goal is to identify at‐risk patients/couples and offer them reproductive options such as preimplantation genetic diagnosis, prenatal testing, or targeted newborn
Emily B. Rosenfeld, Nicole Kasatkin, Bi Liu Yu, Milen Velinov, Justin S. Brandt, Elena Ashkinadze   +5 more
wiley   +1 more source

X-linked familial hypophosphatemia

Arab Journal of Rheumatology
Abstract: Osteomalacia is a diffuse bone disorder characterized by increased bone fragility, and it represents in adults the equivalent of rickets seen in children, sharing the same causes. This condition mainly results from Vitamin D deficiency, but in some cases, it may be due to renal phosphate wasting, which can be hereditary, acquired ...
Boutaina Zerouali, Kawtar Nassar, Soukaina Zaher, Ahlam Ajerouassi, Wafae Rachidi, Saadia Janani   +5 more
openaire   +1 more source

Lack of effect of vitamin D and its metabolites on intestinal phosphate transport in familial hypophosphatemia of mice.

, 1977
Intestinal calcium and phosphate transport was studied in normal and hypophosphatemic mice fed a variety of dietary regimens with and without vitamin D. Regardless of dietary phosphorus levels, the genetic hypophosphatemic mice had drastically reduced
O\u27Doherty, P J, Eicher, E M, DeLuca, H F   +2 more
core  

National Bleeding Disorder Foundation Clinical Practice Recommendations for Laboratory Screening of Iron Deficiency With and Without Anemia in the Inherited Bleeding Disorders Population

Haemophilia, Volume 32, Issue 3, Page 646-657, May/June 2026.
ABSTRACT Introduction The National Bleeding Disorder Foundation (NBDF) Medical and Scientific Advisory Council (MASAC) was formed in 1954 and issues recommendations and advisories pertinent to the bleeding disorders community. MASAC is comprised of > 25 rotating members from different medical disciplines and lived experience experts.
Glaivy Batsuli, Magdalena D. Lewandowska, Ming Y. Lim, Kelly Tickle, Maureen K. Baldwin, Rose Bender, Jennifer Davila, Brendan Hayes, Amanda Jacobson‐Kelly, Peter Kouides, Michele P. Lambert, Shilpa Nataraj, Michelle Sholzberg, Roona Sinha, Hanny Al‐Samkari, Amy L. Dunn   +15 more
wiley   +1 more source

Anxiety Disorder Types From a Metabolomics Perspective: A Mendelian Randomization Analysis Based on 1400 Plasma Metabolites

Brain and Behavior, Volume 16, Issue 4, April 2026.
This study investigates the causal relationship between plasma metabolites and three common types of anxiety disorders using Mendelian randomization analysis. Our findings propose a novel direction for utilizing metabolites as biomarkers in the diagnosis and treatment of anxiety disorders.
Zhen Xiao, Zedi Wu, Zixin Chen, Ziyue Xu, Qi Zhou, Silan Liu, Muqing Wang, Shujun Hou, Wanling Liu, Zhengyi Li, Kunping Xun, Ning Zhang, Chun Wang   +12 more
wiley   +1 more source

Rare PHEX intron variant causes complete and severe phenotype in a family with hypophosphatemic rickets: a case report

, 2022
Objectives Lower limb deformities in children need careful orthopedic evaluation to distinguish physiological forms from pathological ones. X-linked hypophosphatemia (XLH) is a rare hereditary condition caused by PHEX gene mutations where tibial varum ...
Digitale, Lucia, Festa, Adalgisa, Schiano di Cola, Roberta, Aiello, Francesca, Luongo, Caterina, Pasquali, Daniela, Carotenuto, Raffaela, Baronio, Federico, Di Fraia, Rosa, Grandone, Anna, Del Giudice, Emanuele Miraglia, Maltoni, Giulio, Cassio, Alessandra, Rossi, Cesare   +13 more
core   +1 more source

Supplementary Material for: A Familial Case of a Whole Germline CDC73 Deletion Discordant for Primary Hyperparathyroidism

, 2019
Introduction: Primary hyperparathyroidism (PHPT) occurs as part of familial syndromes, including CDC73-related disorders caused by germline pathogenic variants of the CDC73 gene, particularly in early adulthood.
Komiyama O. (6314987), Matsunaga T. (6314996), Yamazawa K. (6314999), Tsutsui H. (6314990), Nagao T. (4106701), Suzuki E. (3230100), Ishii T. (3126300), Hasegawa T. (3126303), Hatabu N. (6314981), Sato T. (3363755), Nakauchi-Takahashi H. (6314993), Katori N. (6314984), Maeda N. (4119259)   +12 more
core   +1 more source