Results 101 to 110 of about 24,867 (235)

Phase 1/2 Study of Crizotinib in Children With Relapsed/Refractory ALK‐Positive Anaplastic Large Cell Lymphoma or Neuroblastoma in Japan

open access: yesCancer Science, Volume 117, Issue 3, Page 777-786, March 2026.
The safety and antitumor activity of crizotinib at a dose of 165 mg/m2 BID were evaluated in 16 patients with ALK‐positive ALCL in Japan. The most common grade 3 or 4 adverse event was neutropenia. The steady‐state Cmax and AUCtau of crizotinib at 165 mg/m2 BID were higher than expected. The objective response rate was 72.7% (90% CI, 43.6%–92.1%) among
Tetsuya Mori   +12 more
wiley   +1 more source

FGF23, Hypophosphatemia, and Emerging Treatments

open access: yesJBMR Plus, 2019
FGF23 is an important hormonal regulator of phosphate homeostasis. Together with its co‐receptor Klotho, it modulates phosphate reabsorption and both 1α‐hydroxylation and 24‐hydroxylation in the renal proximal tubules.
Erik A Imel   +3 more
doaj   +1 more source

Identification of a novel loss-of-function PHEX mutation, Ala720Ser, in a sporadic case of adult-onset hypophosphatemic osteomalacia [PDF]

open access: yes, 2018
Adults presenting with sporadic hypophosphatemia and elevations in circulating fibroblast growth factor-23 (FGF23) concentrations are usually investigated for an acquired disorder of FGF23 excess such as tumor induced osteomalacia (TIO). However, in some
Alan Sorani   +38 more
core   +1 more source

Understanding Why Grey Squirrels (Sciurus carolinensis) Bark Strip in British Woodlands: A Systematic Map

open access: yesMammal Review, Volume 56, Issue 1, March 2026.
Studies investigating the bark‐stripping behaviour of squirrel species that cause economic damage focus on developing methods to manage the behaviour. On the other hand, studies investigating the behaviour of species that do not cause economic damage focus on understanding the behavioural ecology of the species to meet conservation objectives. ABSTRACT
Alexandra K. Ash   +6 more
wiley   +1 more source

The Association of Hypophosphatemia With Resistant Lactic Acidosis in Critical Care Illness

open access: yesJournal of Investigative Medicine High Impact Case Reports, 2020
Critically ill patients are known to have a variety of electrolyte abnormalities. Lactic acidosis can frequently be seen secondary to shock states and is usually treated with aggressive volume resuscitation. Interestingly, hypophosphatemia is a potential
Amr Essa MD   +5 more
doaj   +1 more source

Prevention and Management of Refeeding Syndrome [PDF]

open access: yes, 2016
Refeeding Syndrome is a syndrome which occurs as a result of food administration in poorly nourished individuals. In this syndrome, there are wide range of biochemical alterations, clinical manifestations, and complications, starting from mild ...
Indrarespati, A. (Andika)   +1 more
core   +1 more source

Abnormal serum phosphorus was associated with the outcome of community-acquired pneumonia

open access: yesFrontiers in Nutrition
ObjectiveThe present study aimed to explore the relationship between serum phosphorus levels and outcomes in patients with community-acquired pneumonia (CAP).MethodsThis research was a retrospective, single-center study conducted on adult patients who ...
Si-Qiong Wang   +3 more
doaj   +1 more source

A case of severe osteomalacia secondary to phosphate diabetes in a renal transplant recipient [PDF]

open access: yes, 2013
Transient hypophosphatemia is frequently observed during the first months after renal transplantation and is usually asymptomatic. Phosphate diabetes is defined as inadequate tubular phosphorus reabsorption leading to persistent renal phosphorus wasting,
D. Chappard   +4 more
core   +2 more sources

Hypophosphatemia Due to Adefovir Treatment [PDF]

open access: yesMediterranean Journal of Infection, Microbes and Antimicrobials, 2012
Adefovir dipivoxil is an orally effective prodrug excreted unchanged in urine by glomerular filtration and tubular secretion. While it effectively suppresses hepatitis B virus replication, it may cause nephrotoxicity characterized by severe ...
Nazlım AKTUĞ DEMİR   +4 more
doaj  

Symptomatic severe hypophosphatemia after intravenous ferric carboxymaltose

open access: yesJGH Open, 2019
Intravenous iron is commonly prescribed for treatment of iron deficiency, with modern formulations demonstrating an acceptable safety profile in the majority of patients.
Wendy Fang   +3 more
doaj   +1 more source

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